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161. “Thinking about the future, what’s gonna happen?”—How young people in Sweden who neither work nor study perceive life experiences in relation to health and well-being (PubMed)

unemployed and not eligible for upper secondary school, or who had dropped out of school.Three themes emerged from the analysis illustrating how the young people perceive their life experiences in relation to health and well-being: Struggling with hardships in the absence of caring connections, Feeling good when closely connected to others, and Being forced to question what has been taken for granted. Each theme consists of 2-3 subthemes.Based on the young people's narrated experiences health can (...) “Thinking about the future, what’s gonna happen?”—How young people in Sweden who neither work nor study perceive life experiences in relation to health and well-being The aim of this study was to explore how young people in Sweden who neither work nor study perceive life experiences in relation to health and well-being.A task-based interview technique was used and data was analysed with qualitative content analysis. Interviews were conducted with 16 participants aged 16-20 who were

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2018 International journal of qualitative studies on health and well-being

162. How many people have been bitten by dogs? A cross-sectional survey of prevalence, incidence and factors associated with dog bites in a UK community (PubMed)

How many people have been bitten by dogs? A cross-sectional survey of prevalence, incidence and factors associated with dog bites in a UK community Dog bite studies are typically based on hospital records and may be biased towards bites requiring significant medical treatment. This study investigated true dog bite prevalence and incidence at a community-level and victim-related risk factors, in order to inform policy and prevention.A cross-sectional study of a community of 1280 households (...) requires further investigation and potential consideration in the design of bite prevention schemes.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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2018 Journal of epidemiology and community health

163. SECURE PCI: how important can a subgroup analysis be? (PubMed)

SECURE PCI: how important can a subgroup analysis be? 30023111 2018 11 14 2072-1439 10 Suppl 17 2018 Jun Journal of thoracic disease J Thorac Dis SECURE PCI: how important can a subgroup analysis be? S2032-S2034 10.21037/jtd.2018.05.155 Kerneis Mathieu M Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Yee Megan K MK Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess (...) Medical Center, Harvard Medical School, Boston, MA, USA. Gibson C Michael CM Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. eng Editorial Comment China J Thorac Dis 101533916 2072-1439 JAMA. 2018 Apr 3;319(13):1331-1340 29525821 Conflicts of Interest: M Kerneis has received research grant support from French federation of Cardiology, Institut Servier, consulting fees or honorarium from Bayer and AstraZeneca

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2018 Journal of thoracic disease

164. Estimating Drug Costs: How do Manufacturer Net Prices Compare with Other Common US Price References? (PubMed)

Estimating Drug Costs: How do Manufacturer Net Prices Compare with Other Common US Price References? Drug costs are frequently estimated in economic analyses using wholesale acquisition cost (WAC), but what is the best approach to develop these estimates? Pharmaceutical manufacturers recently released transparency reports disclosing net price increases after accounting for rebates and other discounts.Our objective was to determine whether manufacturer net prices (MNPs) could approximate (...) granted to the VA, suggesting they may be a useful proxy for the true pharmacy benefits manager (PBM) or payer cost. However, individual discounts for products have wide variation, making a standard discount adjustment across multiple products less acceptable.

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2018 PharmacoEconomics

165. Operational research within a Global Fund supported tuberculosis project in India: why, how and its contribution towards change in policy and practice (PubMed)

Operational research within a Global Fund supported tuberculosis project in India: why, how and its contribution towards change in policy and practice The Global Fund encourages operational research (OR) in all its grants; however very few reports describe this aspect. In India, Project Axshya was supported by a Global Fund grant to improve the reach and visibility of the government Tuberculosis (TB) services among marginalised and vulnerable communities. OR was incorporated to build research (...) capacity of professionals working with the national TB programme and to generate evidence to inform policies and practices.To describe how Project Axshya facilitated building OR capacity within the country, helped in addressing several TB control priority research questions, documented project activities and their outcomes, and influenced policy and practice.From September 2010 to September 2016, three key OR-related activities were implemented. First, practical output-oriented modular training courses

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2018 Global health action

166. "I prefer dying fast than dying slowly", how institutional abuse worsens the mental health of stranded Syrian, Afghan and Congolese migrants on Lesbos island following the implementation of EU-Turkey deal (PubMed)

"I prefer dying fast than dying slowly", how institutional abuse worsens the mental health of stranded Syrian, Afghan and Congolese migrants on Lesbos island following the implementation of EU-Turkey deal In 2015 and early 2016, close to 1 million migrants transited through Greece, on their way to Western Europe. In early 2016, the closure of the "Balkan-route" and the EU/Turkey-deal led to a drastic reduction in the flow of migrants arriving to the Greek islands. The islands became open (...) detention centers, where people would spend months or years under the constant fear of being returned to Turkey.Syrians were generally granted refugee status in Greece and those arrived before the 20th of March 2016 had the option of being relocated to other European countries. Afghans had some chances of being granted asylum in Greece, whilst most migrants from the Democratic Republic of Congo were refused asylum.In a clinic run by Médecins sans Frontières on Lesbos Island, psychologists observed

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2018 Conflict and health

167. How does the UK childcare energy-balance environment influence anthropometry of children aged 3-4 years? A cross-sectional exploration. (PubMed)

How does the UK childcare energy-balance environment influence anthropometry of children aged 3-4 years? A cross-sectional exploration. To assess the association between time spent in care, the childcare energy-balance environment, and preschool-aged children's body mass index z-score (z-BMI), waist-to-height ratio (WHR) and sum of skinfold thickness (SST).Cross-sectional study.Children aged 3-4 years were recruited from 30 childcare centres in Cambridgeshire (UK) in 2013.Objectively measured (...) prevention strategies for young children.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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2018 BMJ open

168. How do Australian women cope with pelvic girdle pain during pregnancy? A qualitative study protocol. (PubMed)

How do Australian women cope with pelvic girdle pain during pregnancy? A qualitative study protocol. Pelvic girdle pain is commonly experienced during pregnancy and results in significant physical, psychosocial and work-related challenges. Few studies have investigated the lived experiences of pregnant women with pelvic girdle pain and their coping strategies. There is a need to develop a greater understanding of this prevalent condition among Australian women. Thus, this study seeks to gain (...) information about the impact of pelvic girdle pain on daily life and how women cope with this condition during pregnancy.A qualitative research design, situated within a phenomenological framework, is adopted. The participants will be invited to describe their lived experiences of pregnancy-related pelvic girdle pain, the impact on their daily life and the strategies they use to cope with the condition. A stratified purposive sample will be undertaken to ensure the sample provides information-rich cases

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2018 BMJ open

169. Building the Child Safety Collaborative Innovation and Improvement Network: How does it work and what is it achieving? (PubMed)

Building the Child Safety Collaborative Innovation and Improvement Network: How does it work and what is it achieving? This study investigated whether the Child Safety Collaborative Innovation and Improvement Network (CS CoIIN) framework could be applied in the field of injury and violence prevention to reduce fatalities, hospitalizations and emergency department visits among 0-19 year olds.Twenty-one states/jurisdictions were accepted into cohort 1 of the CS CoIIN, and 14 were engaged from (...) indicates the CS CoIIN framework can be applied to make progress on process measures, but more time is needed to determine if this will result in progress on long-term outcome measures of fatalities, hospitalizations and emergency department visits. Seventeen states/jurisdictions will participate in cohort 2.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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2018 Injury Prevention

170. How can virtual care fix the health care industrial complex?

How can virtual care fix the health care industrial complex? How can virtual care fix the health care industrial complex? How can virtual care fix the health care industrial complex? | | September 13, 2018 19 Shares The health care industry is experiencing a crisis. There’s a . And as a result, doctors are working long hours that are affecting their stress levels, increasing burnout rates, health and the ability to diagnose their patients properly. This piece will discuss the many solutions (...) what needs to change, and how can medical practices create better environments for doctors to thrive? The challenges physicians face in providing the best quality of their career Having worked with some of the most vulnerable populations in my past life as a doctor at a VA clinic, I experienced how working long hours and navigating complex patient relationships negatively impacted my quality of life and my quality of care. I remember one particular unhoused Veteran whom I suspected was selling

2018 KevinMD blog

171. It’s time to change how we regulate methadone

It’s time to change how we regulate methadone It’s time to change how we regulate methadone It’s time to change how we regulate methadone | | September 13, 2018 23 Shares In 2016, dispatchers in my hometown of Mansfield — a Rust Belt city in rural North Central Ohio — fielded over 363 overdose-related police calls. The community organized an opiate response team, created to help individuals following an overdose, which could only respond to those experiencing their second overdose. Around (...) and Congress should act to authorize approved providers at outpatient clinics to prescribe methadone. Granting this power to outpatient clinics such as federally qualified health centers and rural health clinics would vastly expand access to care. Reforming prescription rules at outpatient centers would bring the U.S. into line with existing systems in Australia and Canada. In both countries, this change expanded rural access to methadone by allowing approved primary care providers and pharmacies

2018 KevinMD blog

172. How a deliberative approach includes women in the decisions of screening mammography: a citizens' jury feasibility study in Andalusia, Spain. (PubMed)

How a deliberative approach includes women in the decisions of screening mammography: a citizens' jury feasibility study in Andalusia, Spain. To verify whether a citizens' jury study is feasible to the Andalusian population and to know if women, when better informed, are able to answer the research question of whether the Andalusian Public Health System must continue offering screening mammography to women aged 50-69. The reasons for the pertinent decision and recommendations to the political (...) desire informed decision making and to keep or increase medicalisation in their lives.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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2018 BMJ open

173. T-piece resuscitators: how do they compare? (PubMed)

T-piece resuscitators: how do they compare? The T-piece resuscitator (TPR) has seen increased use as a primary resuscitation device with newborns. Traditional TPR design uses a high resistance expiratory valve to produce positive end expiratory pressure (PEEP) or continuous positive airway pressure (CPAP) at resuscitation. A new TPR device that uses a dual flow ratio valve (fluidic flip) to produce PEEP/CPAP is now available (rPAP). We aimed to compare the measured ventilation performance (...) compliances expected at birth. Device-generated inadvertent PEEP and overdelivery of PIP may be clinically deleterious for term and preterm newborns or infants with larger Crs during resuscitation.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2019. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

2018 Archives of Disease in Childhood. Fetal and Neonatal Edition

174. How effective and cost-effective are behaviour change interventions in improving the prescription and use of antibiotics in low-income and middle-income countries? A protocol for a systematic review. (PubMed)

How effective and cost-effective are behaviour change interventions in improving the prescription and use of antibiotics in low-income and middle-income countries? A protocol for a systematic review. Antibiotic resistance endangers effective prevention and treatment of infections, and places significant burden on patients, families, communities and healthcare systems. Low-income and middle-income countries (LMICs) are especially vulnerable to antibiotic resistance, owing to high infectious (...) of Recommendation, Assessment, Development and Evaluation (GRADE) checklist.No individual patient data are used, so ethical approval is not required. The systematic review will be disseminated in a peer-reviewed journal and presented at a relevant international conference.CRD42017075596.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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2018 BMJ open

175. How to prevent and manage radiation-induced coronary artery disease. (PubMed)

How to prevent and manage radiation-induced coronary artery disease. Radiation-induced coronary heart disease (RICHD) is the second most common cause of morbidity and mortality in patients treated with radiotherapy for breast cancer, Hodgkin's lymphoma and other prevalent mediastinal malignancies. The risk of RICHD increases with radiation dose. Exposed patients may present decades after treatment with manifestations ranging from asymptomatic myocardial perfusion defects to ostial, triple (...) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

2018 Heart

176. Review article: A primer for clinical researchers in the emergency department: Part VII. Considering a research higher degree in emergency medicine: How does it work, where to start, what to consider. (PubMed)

Review article: A primer for clinical researchers in the emergency department: Part VII. Considering a research higher degree in emergency medicine: How does it work, where to start, what to consider. In this series we address important topics for clinicians who participate in research or are considering research as part of their career path in emergency medicine. While much emergency research is successfully done by clinicians without a research higher degree (RHD), undertaking a master's (...) degree or doctorate allows a research topic to be pursued in greater depth. It also provides a solid basis for a future research career in terms of research quality, advanced skills, academic progression and track record, as well as eligibility for grants and RHD supervision. The decision to undertake a RHD is not an easy one, and requires consideration of the time and cost involved, as well as the impact on a clinician's life plans. However, the expertise provided through a RHD often ultimately

2018 Emergency medicine Australasia

177. How Much Blood Could a JP Suck If a JP Could Suck Blood? (PubMed)

How Much Blood Could a JP Suck If a JP Could Suck Blood? Active surgical drains minimize fluid accumulation in the postoperative period. The Jackson-Pratt (JP) system consists of a silicone drain connected by flexible tubing to a bulb. When air in the bulb is evacuated, negative pressure is applied at the surgical site to aspirate fluid. The objective of this study was to determine if the evacuation method and volume of accumulated fluid affect the pressure generated by the bulb.Bulbs were (...) a side-in evacuation of a JP bulb was 87.4 cm H2 O compared to 17.7 cm H2 O for a bottom-up evacuation (P < 0.0001). When the drain contained 25 mL, 50 mL, 75 mL, and 100 mL of fluid, the pressure applied dropped to 72.6, 41.3, 37.0, and 35.6 cm H2 O, respectively.JP drains generate negative pressure in order to reduce fluid accumulation at surgical sites. Although its function is frequently taken for granted, this study demonstrates that both the specific method for evacuating the bulb as well

2018 Laryngoscope

178. How does exercise dose affect patients with long-term osteoarthritis of the knee? A study protocol of a randomised controlled trial in Sweden and Norway: the SWENOR Study. (PubMed)

How does exercise dose affect patients with long-term osteoarthritis of the knee? A study protocol of a randomised controlled trial in Sweden and Norway: the SWENOR Study. Osteoarthritis (OA) of the knee is characterised by knee pain, disability and degenerative changes, and places a burden on societies all over the world. Exercise therapy is an often-used modality, but there is little evidence of what type of exercise dose is the most effective, indicating a need for controlled studies (...) and presented at national and international conferences.NCT02024126; Pre-results.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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2018 BMJ open Controlled trial quality: predicted high

179. Negative affect, message reactance and perceived risk: how do pictorial cigarette pack warnings change quit intentions? (PubMed)

Negative affect, message reactance and perceived risk: how do pictorial cigarette pack warnings change quit intentions? Pictorial warnings on cigarette packs increase motivation to quit smoking. We sought to examine the potential mediating role of negative affect, message reactance (ie, an oppositional reaction to a message) and perceived risk in shaping quit intentions.In 2014 and 2015, we randomly assigned 2149 adult US smokers to receive either pictorial warnings or text-only warnings (...) by increasing negative affect. Message reactance partially attenuated this increase in intentions. The opposing associations of negative affect and reactance on perceived risk may explain why pictorial warnings did not lead to observable changes in perceived risk.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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2018 Tobacco Control

180. How good are GPs at adhering to a pragmatic trial protocol in primary care? Results from the ADDITION-Cambridge cluster-randomised pragmatic trial. (PubMed)

How good are GPs at adhering to a pragmatic trial protocol in primary care? Results from the ADDITION-Cambridge cluster-randomised pragmatic trial. To assess the fidelity of general practitioners' (GPs) adherence to a long-term pragmatic trial protocol.Retrospective analyses of electronic primary care records of participants in the pragmatic cluster-randomised ADDITION (Anglo-Danish-Dutch Study of Intensive Treatment In People with Screen Detected Diabetes in Primary Care)-Cambridge trial (...) to be considered as they have the potential to dilute differences in treatment intensity and hence incremental effects.ISRCTN86769081.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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2018 BMJ open

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