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17741. Iodine I 131 With or Without Thyroid-Stimulating Hormone in Treating Patients Who Have Undergone Surgery for Thyroid Cancer

Responsible Party: University College, London ClinicalTrials.gov Identifier: Other Study ID Numbers: CDR0000522490 CRUK-HILO-BRD/05/83 ( Other Grant/Funding Number: Cancer Research UK ) ISRCTN56078540 ( Registry Identifier: ISRCTN ) EU-20665 CTA-20363/0217/001/0001 ( Other Identifier: Regulatory Authority Number ) 2005-003687-37 ( EudraCT Number ) First Posted: December 22, 2006 Last Update Posted: October 16, 2018 Last Verified: October 2017 Keywords provided by University College, London: stage I (...) : This randomized phase III trial is studying two different doses of iodine I 131 to compare how well they work when given with or without thyroid-stimulating hormone in treating patients who have undergone surgery for thyroid cancer. Condition or disease Intervention/treatment Phase Head and Neck Cancer Biological: recombinant thyroid-stimulating hormone Radiation: Radiodine ablation without rhTSH Phase 3 Detailed Description: OBJECTIVES: Primary Compare the percentage of successful remnant ablation at 6-8

2006 Clinical Trials

17742. Impact of Umbilical Cord Cleansing With 4.0% Chlorhexidine on Neonatal Mortality

Responsible Party: Dr. Abdullah H. Baqui, Professor, Johns Hopkins Bloomberg School of Public Health ClinicalTrials.gov Identifier: Other Study ID Numbers: IRB00000146 GHSA00030001900 ( Other Grant/Funding Number: Save the Children 131 ) First Posted: February 13, 2007 Last Update Posted: August 10, 2011 Last Verified: July 2007 Keywords provided by Johns Hopkins Bloomberg School of Public Health: omphalitis neonates umbilical cord infection infant mortality neonate morbidity chlorhexidine Additional (...) cleansing of the cord demonstrated in the Nepal trial, a replication study of this regimen and further investigations of more simple regimens are necessary. The number of treatments necessary to reduce neonatal mortality has important programmatic implications for who can deliver the intervention, and how it is packaged. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 28797 participants Allocation: Randomized Intervention Model

2007 Clinical Trials

17743. Concurrent Once Daily Versus Twice Daily Radiotherapy for Limited Stage Small Cell Lung Cancer

Faivre-Finn, MD The Christie NHS Foundation Trust More Information Go to Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number): Layout table for additonal information Responsible Party: Sally Falk, Prof Corinne Faivre-Finn, The Christie NHS Foundation Trust ClinicalTrials.gov Identifier: Other Study ID Numbers: CDR0000531709 CHNT-CONVERT ( Other Identifier: Christie Hospital NHS Foundation Trust ) CHNT-CTAAC-CONVERT-C17052/A815 ( Other Grant/Funding Number (...) in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known which schedule of radiation therapy is more effective when given together with chemotherapy in treating small cell lung cancer. PURPOSE: This randomized phase III trial is studying two different schedules of radiation therapy to compare how well they work when given together with cisplatin and etoposide

2007 Clinical Trials

17744. O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy

: RATIONALE: Drugs used in chemotherapy, such as O(6)-benzylguanine and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase II trial is studying the side effects and how well giving O(6)-benzylguanine together with temozolomide works in treating patients with glioblastoma multiforme that did not respond to previous (...) , radiotherapy, immunotherapy, or investigational agents Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00436436 Locations Layout table for location information United States, Maryland Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral

2007 Clinical Trials

17745. Diabetes Genome Project: A Prospective Registry to Identify Genetic Variation Among Diabetic Patients

: January 10, 2013 Sponsor: Saint Luke's Health System Information provided by (Responsible Party): Steven P. Marso, Saint Luke's Health System Study Details Study Description Go to Brief Summary: Previous scientific research has found multiple genes that affect the risk for developing heart disease or complications during the treatment of heart disease. Less is currently known about how patients with heart disease may differ on the basis of other ailments they may have and how these other ailments may (...) affect their treatment and prognosis. For this reason, researchers at the Mid America Heart Institute are conducting this research to find out how genes affect heart disease and recovery following angioplasty. The study will include patients with diabetes in order to determine if their genes are different from patients without diabetes. A total of 1,607 patients were enrolled. There were 2 groups of patients selected for this study. The first group of patients included into the study will be those

2007 Clinical Trials

17746. Neurovascular Coupling in Eyes of Glaucoma Patients

Director: Selim Orgül, MD University Eye Clinic Basel More Information Go to Layout table for additonal information Responsible Party: University Hospital, Basel, Switzerland ClinicalTrials.gov Identifier: Other Study ID Numbers: 084-GUK-2006-002 Swiss National Foundation ( Other Grant/Funding Number: 3200B0-113685 ) First Posted: February 1, 2007 Last Update Posted: December 16, 2014 Last Verified: December 2014 Additional relevant MeSH terms: Layout table for MeSH terms Glaucoma Ocular Hypertension (...) Study Description Go to Brief Summary: We hypothesize that glaucoma patients demonstrate an impaired retinal vascular response to the flicker stimulus, and that this disturbance is predictive of the progression of glaucomatous damage. The response of a major temporal superior and inferior retinal artery and vein to a 60 seconds 12.5 Hz flicker light stimulation in 50 glaucoma patients, 50 ocular hypertensives and 50 controls (using the Retinal Vessel Analyzer) and to investigate how intraocular

2007 Clinical Trials

17747. AZD2171 in Treating Patients With Locally Advanced Unresectable or Metastatic Liver Cancer

Investigator: Andrew Zhu Massachusetts General Hospital More Information Go to Additional Information: Publications of Results: Layout table for additonal information Responsible Party: National Cancer Institute (NCI) ClinicalTrials.gov Identifier: Other Study ID Numbers: NCI-2009-00130 05-311 ( Other Identifier: DFHCC IRB ) N02CO12400 ( Other Grant/Funding Number: US NIH Grant/Contract Award Number ) CDR0000526405 ( Registry Identifier: PDQ (Physician Data Query) ) First Posted: January 29, 2007 Results (...) Posted : October 31, 2016 Last Update Posted : October 31, 2016 Sponsor: National Cancer Institute (NCI) Information provided by (Responsible Party): National Cancer Institute (NCI) Study Details Study Description Go to Brief Summary: This phase II trial is studying how well AZD2171 works in treating patients with locally advanced unresectable or metastatic liver cancer. AZD2171 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow

2007 Clinical Trials

17748. Neurovascular Coupling in Eyes of Glaucoma Patients

: University Hospital, Basel, Switzerland ClinicalTrials.gov Identifier: Other Study ID Numbers: 083-GUK-2006-001 Swiss National Foundation ( Other Grant/Funding Number: 3200B0-113685 ) First Posted: February 1, 2007 Last Update Posted: December 11, 2013 Last Verified: December 2013 Additional relevant MeSH terms: Layout table for MeSH terms Glaucoma Ocular Hypertension Eye Diseases (...) Study Description Go to Brief Summary: We hypothesize that glaucoma patients demonstrate an impaired retinal vascular response to the flicker stimulus, and that this disturbance is predictive of the progression of glaucomatous damage. The response of a major temporal superior and inferior retinal artery and vein to a 60 seconds 12.5 Hz flicker light stimulation in 50 glaucoma patients, 50 ocular hypertensives and 50 controls (using the Retinal Vessel Analyzer) and to investigate how intraocular

2007 Clinical Trials

17749. Study Combining Imatinib Mesylate (Gleevec) With Sorafenib in Patients With Androgen-independent Prostate Cancer (AIPC)

to 90 Years (Adult, Older Adult) Sexes Eligible for Study: Male Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Patients 18 years of age or older. Histologically documented diagnosis of Prostate Cancer regardless of Gleason score. Androgen-Independent Prostate Cancer At least one measurable site of disease Patients must have failed one or more lines of systemic chemotherapy, regardless of the chemotherapeutic agent used. There is NO limit to how many lines of chemotherapy a patient can (...) chronic liver disease (i.e., chronic active hepatitis, and cirrhosis). Patient has a known diagnosis of human immunodeficiency virus (HIV) infection. Patient previously received radiotherapy to ³ 25 % of the bone marrow Patient had a major surgery within 2 weeks prior to study entry. Patient with any significant history of non-compliance to medical regimens or with inability to grant reliable informed consent. Contacts and Locations Go to Information from the National Library of Medicine To learn more

2007 Clinical Trials

17750. Radiation Doses and Fractionation Schedules in Non-low Risk Ductal Carcinoma In Situ (DCIS) of the Breast

Numbers: TROG 07.01 NHMRC 454390 ( Other Grant/Funding Number: NHMRC ) BIG 3-07 ( Other Identifier: Collaborative Group ) NCIC CTG MA.33 ( Other Identifier: Collaborative Group ) BOOG 2009-03 ( Other Identifier: Collaborative Group ) ICORG 10-06 ( Other Identifier: Collaborative Group ) EORTC 22085-10083 ( Other Identifier: Collaborative Group ) IBCSG 38-10 ( Other Identifier: Collaborative Group ) SCTBG 2009MayPR55 ( Other Identifier: Collaborative Group ) First Posted: May 7, 2007 Last Update Posted

2007 Clinical Trials

17751. Arthritis Self-Management Education Program

Study ID Numbers: 06-0398-1-3 S3521-24/24 ( Other Grant/Funding Number: CDC ) First Posted: April 27, 2007 Last Update Posted: January 28, 2010 Last Verified: January 2010 Keywords provided by University of North Carolina, Chapel Hill: Disease self-management Community programs Additional relevant MeSH terms: Layout table for MeSH terms Arthritis Joint Diseases Musculoskeletal Diseases

2007 Clinical Trials

17752. Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment

for investigator information Principal Investigator: Juliana B Diniz, MD University of Sao Paulo Medical School More Information Go to Additional Information: Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number): Layout table for additonal information Responsible Party: Juliana Belo Diniz, MD, PhD, University of Sao Paulo ClinicalTrials.gov Identifier: Other Study ID Numbers: 05/55628-8 2005/55628-08 ( Other Grant/Funding Number: FAPESP ) First Posted: April 27, 2007

2007 Clinical Trials

17753. Effect of Daily Calorie or Alternate-day Calorie Reductions on Risk for Cardiovascular Disease and Cancer

Sponsors and Collaborators University of California, San Francisco National Institutes of Health (NIH) Investigators Layout table for investigator information Principal Investigator: Marc Hellerstein, MD, PhD University of California, Berkeley; University of California, San Francisco More Information Go to Layout table for additonal information Responsible Party: University of California, San Francisco ClinicalTrials.gov Identifier: Other Study ID Numbers: H3049-30095-01 NIH-PPG ( Other Grant/Funding

2007 Clinical Trials

17754. Role of Placenta Growth Factor in Sickle Acute Chest Syndrome

for additonal information Responsible Party: Children's Hospital Medical Center, Cincinnati ClinicalTrials.gov Identifier: Other Study ID Numbers: CCHMC 06-09-57 R01 ( Other Grant/Funding Number: HL079916 ) First Posted: March 16, 2007 Last Update Posted: December 21, 2017 Last Verified: December 2017 Keywords provided by Children's Hospital Medical Center, Cincinnati: Anemia, sickle cell Additional relevant MeSH terms: Layout table for MeSH terms Anemia, Sickle Cell Acute Chest Syndrome Anemia, Hemolytic

2007 Clinical Trials

17755. Integrated Treatment to Persons With Mental Disorders and Co-occurring Substance Use Disorders

Identifier: Other Study ID Numbers: 78i068 NFR175394/V50 ( Other Grant/Funding Number: The Norwegian Research Council/NFR175394/V50 ) First Posted: March 15, 2007 Last Update Posted: March 26, 2012 Last Verified: March 2012 Keywords provided by Rolf W. Grawe, University of Oslo: mental health substance use treatment Additional relevant MeSH terms: Layout table for MeSH terms Disease Anxiety Disorders Mental Disorders Psychotic Disorders Mood Disorders Substance-Related Disorders Pathologic Processes

2007 Clinical Trials

17756. Study of Dust Mite Inhalation in Humans

Carolina, Chapel Hill ClinicalTrials.gov Identifier: Other Study ID Numbers: 06-0528 NHLBI-RO1 HL080337 ( Other Grant/Funding Number: National Heart, Lung, and Blood Institute (NHLBI) ) First Posted: March 19, 2007 Last Update Posted: December 10, 2013 Last Verified: December 2013 Keywords provided by David B. Peden, MD, University of North Carolina, Chapel Hill: asthma allergy (...) , University of North Carolina, Chapel Hill Study Details Study Description Go to Brief Summary: The purpose of this research study is to learn more about the effect of inhaled dust mite allergen extract on airway responses in allergic individuals with mild asthma. Information learned from this study will be used to identify a safe dose range of D Farinae extract for use in inhalation challenge studies. This study will also help determine how inhalation of the allergen affects mucociliary clearance (MCC

2007 Clinical Trials

17757. Safety Study of CAT-8015 Immunooxin in Patients With HCL With Advance Disease

or disease progression. Patients are followed at 1, 3, 6,12,15,18, 21, 24 months following the start of the last treatment cycle. Cohorts of 3-6 patients each will receive escalating doses of recombinant CAT-8015 until the maximum tolerated dose (MTD) is determined. The MTD is defined as the dose proceeding that at which 2 of 3 or 2 of 6 patients experience dose-limiting toxicity. Once the MTD is determined, between16 to 25 new patients will be added to the MTD cohort depending on how well the CAT-8015 (...) University School of Medicine Not yet recruiting Stanford, California, United States, 94305 Contact: Sylvia Quesada, RN 650-725-4041 Principal Investigator: Steven E Coutre, MD United States, Illinois Cancer Center of Northwestern University Not yet recruiting Chicago, Illinois, United States, 60611 Contact: Simbi Acharya 312-695-1383 Principal Investigator: Martin Tallman, MD United States, Maryland Warren Grant Megnuson Clinical Center – NCI Clinical Trials Referral Office Recruiting Bethesda, Maryland

2007 Clinical Trials

17758. Medication and Counseling for Controlled Drinking (Project SMART)

Kuerbis, National Institute on Alcohol Abuse and Alcoholism (NIAAA) Study Details Study Description Go to Brief Summary: The purpose of this study is to study the effectiveness of medication and specialized psychotherapy in helping gay and bisexual men who do not want to quit drinking learn how to reduce their drinking to healthier levels. More information on the study is available at www.projectsmartnyc.org. Condition or disease Intervention/treatment Phase Alcohol-related Disorders Alcohol Drinking (...) and Alcoholism (NIAAA) Investigators Layout table for investigator information Principal Investigator: Jon Morgenstern, PhD Columbia University More Information Go to Layout table for additonal information Responsible Party: Alexis Kuerbis, Co-Investigator, National Institute on Alcohol Abuse and Alcoholism (NIAAA) ClinicalTrials.gov Identifier: Other Study ID Numbers: NIAAAMOR_015553-01A1S1 NIH Grant AA015553-01A1S1 First Posted: March 7, 2007 Last Update Posted: May 1, 2013 Last Verified: April 2013

2007 Clinical Trials

17759. The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause

Party: PI - Dr. Angela M. Cheung, University Health Network/University of Toronto ClinicalTrials.gov Identifier: Other Study ID Numbers: 06-0332-AE PSI 06-28 ( Other Grant/Funding Number: The Physicians' Services Incorporated Foundation ) First Posted: January 11, 2007 Last Update Posted: April 8, 2010 Last Verified: October 2008 Keywords provided by University Health Network, Toronto: vibration mechanical loading bone mineral density women's health osteoporosis Additional relevant MeSH terms (...) studies have found that whole-body vibration slowed down bone loss in postmenopausal women. One of the reasons why different studies found different results may be because they used various speeds of vibration. This study looks at how different speeds of whole-body vibration influence bone mineral density differently in postmenopausal women who have osteopenia. Two hundred postmenopausal women will take part in this 12-month study. Women will be randomly assigned into three groups (67 women per group

2007 Clinical Trials

17760. A Study of Taurine in Patients With First-episode Psychosis Receiving Antipsychotic Treatment

by ClinicalTrials.gov Identifier (NCT Number): Layout table for additonal information Responsible Party: Melbourne Health ClinicalTrials.gov Identifier: Other Study ID Numbers: MHREC 2006/040 SMRI Grant ID Number 06T-811 ( Other Grant/Funding Number: Stanley Medical Resarch Institute ) First Posted: January 11, 2007 Last Update Posted: November 20, 2015 Last Verified: November 2015 Keywords provided by Melbourne Health: First Episode Psychosis Additional relevant MeSH terms: Layout table for MeSH terms Psychotic

2007 Clinical Trials

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