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81. How does evidence affect clinical decision-making? Full Text available with Trip Pro

How does evidence affect clinical decision-making? How does evidence affect clinical decision-making? | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here How does evidence affect clinical decision-making? Article Text Original EBM Research How does evidence affect clinical decision-making? Paul Fontelo , Fang Liu , Raymonde C Uy Statistics from Altmetric.com Extract In 1998, the ‘Evidence Cart’ was introduced to provide decision support tools

2015 Evidence-Based Medicine

82. How to do it. Apply for a research grant. Full Text available with Trip Pro

How to do it. Apply for a research grant. 728716 1979 03 28 2016 11 23 0007-1447 2 6151 1978 Dec 02 British medical journal Br Med J How to do it. Apply for a research grant. 1553-4 Howie J J eng Journal Article England Br Med J 0372673 0007-1447 AIM IM Research Support as Topic United Kingdom 1978 12 2 1978 12 2 0 1 1978 12 2 0 0 ppublish 728716 PMC1608768

1978 British medical journal

83. How do researchers conceptualize and plan for the sustainability of their NIH R01 implementation projects? Full Text available with Trip Pro

referenced frameworks with sustainability constructs and offered limited information on how they operationalized frameworks. Researchers described broad categories of approaches and strategies to promote sustainability and key factors that may influence researchers to plan for sustainability, such as personal beliefs, self-efficacy, perception of their role, and the challenges of the grant funding system.We explored how US NIH R01 DIRH grant recipients conceptualized and planned for the sustainability (...) Institutes of Health (NIH).We used sequential, mixed methods to explore how researchers conceptualized and planned for the sustainability of the health interventions using (1) a document review of all active and completed US NIH R01 Grants and Equivalents reviewed within the Dissemination and Implementation Research in Health (DIRH) Study Section between 2004 and 2016 and (2) a qualitative content analysis of semi-structured interviews with NIH R01 DIRH grant recipients.We found 277 R01 profiles within

2019 Implementation Science

84. Resident Autonomy in the Operating Room: How Faculty Assess Real-time Entrustability. (Abstract)

Resident Autonomy in the Operating Room: How Faculty Assess Real-time Entrustability. This study aimed to identify the empirical processes and evidence that expert surgical teachers use to determine whether to take over certain steps or entrust the resident with autonomy to proceed during an operation.Assessing real-time entrustability is inherent in attending surgeons' determinations of residents' intraoperative autonomy in the operating room. To promote residents' autonomy, it is necessary (...) to understand how attending surgeons evaluate residents' performance and support opportunities for independent practice based on the assessment of their entrustability.We conducted qualitative semi-structured interviews with 43 expert surgical teachers from 21 institutions across 4 regions of the United States, using purposeful and snowball sampling. Participants represented a range of program types, program size, and clinical expertise. We applied the Framework Method of content analysis to iteratively

2019 Annals of Surgery

85. Why and how to step down chronic asthma drugs. (Abstract)

Why and how to step down chronic asthma drugs. Asthma is a common chronic airways disease. The goal of asthma management is to control symptoms while minimizing the side effects of treatment. Following a period of stable asthma, clinicians should consider stepping down treatment. This approach is recommended by current guidelines. Step-down has been studied for several types of asthma drug regimens, and certain approaches may have lower risk than others. Systematic reviews of multiple trials (...) trials support an increased risk of asthma exacerbation for patients who completely stop taking inhaled corticosteroid or long acting bronchodilator. Strategies to implement step-down in practice include the use of risk prediction as well as tools to support shared decision making and communication about risk between clinicians and patients.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights

2017 BMJ

86. How to prevent the microvascular complications of type 2 diabetes beyond glucose control. Full Text available with Trip Pro

How to prevent the microvascular complications of type 2 diabetes beyond glucose control. Microvascular complications (retinopathy, nephropathy, and neuropathy) affect hundreds of millions of patients with type 2 diabetes. They usually affect people with longstanding or uncontrolled disease, but they can also be present at diagnosis or in those yet to have a diagnosis made. The presentation and progression of these complications can lead to loss of visual, renal, and neurologic functions (...) , as well as additional proposed interventions that are supported by research published in the past decade. High level evidence sources such as systematic reviews and large, multicenter randomized clinical trials have been prioritized. Smaller trials were included where high quality evidence was unavailable.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

2017 BMJ

87. Global fund financing to the 34 malaria-eliminating countries under the new funding model 2014-2017: an analysis of national allocations and regional grants. Full Text available with Trip Pro

financing to achieve their malaria elimination goals, would receive less funding under the NFM. This study aims to understand the projected increase or decrease in national and regional funding from the GFATM's NFM to the 34 malaria-eliminating countries.Average annual disbursements under the old funding model were compared to average annual national allocations for all eligible 34 malaria-eliminating countries for the period of 2014-2017. Regional grant funding to countries that are due to receive (...) Global fund financing to the 34 malaria-eliminating countries under the new funding model 2014-2017: an analysis of national allocations and regional grants. The Global Fund to Fight AIDS, Tuberculosis, and Malaria (GFATM) has been the largest financial supporter of malaria since 2002. In 2011, the GFATM transitioned to a new funding model (NFM), which prioritizes grants to high burden, lower income countries. This shift raises concerns that some low endemic countries, dependent on GFATM

2016 Malaria journal

88. Developing a Comprehensive Animal Care Occupational Health and Safety Program at a Land-Grant Institution Full Text available with Trip Pro

Developing a Comprehensive Animal Care Occupational Health and Safety Program at a Land-Grant Institution The Public Health Service Policy on the Humane Care and Use of Laboratory Animals and sound ethical practices require institutions to provide safe working environments for personnel working with animals; this mandate is achieved in part by establishing an effective animal care Occupational Health and Safety Program (OHSP). Land-grant institutions often face unique organizational challenges (...) in fulfilling this requirement. For example, responsibilities for providing health and safety programs often have historically been dispersed among many different divisions scattered around the campus. Here we describe how our institutional management personnel overcame organizational structure and cultural obstacles during the formation of a comprehensive campus-wide animal care OHSP. Steps toward establishing the animal care OHSP included assigning overall responsibility, identifying all stakeholders

2016 Journal of the American Association for Laboratory Animal Science : JAALAS

89. Grant Success for Early-Career Faculty in Patient-Oriented Research: Difference-in-Differences Evaluation of an Interdisciplinary Mentored Research Training Program Full Text available with Trip Pro

and awards as principal investigator. Outcomes were compared within cohorts over time (pre- vs. post-period) and across cohorts.From pre- to post-period, mean annual counts and dollars of grant awards increased significantly for both cohorts, but mean annual dollars increased significantly more for the CFSP than for the comparison cohort (delta $83,427 vs. $27,343, P < .01). Mean annual counts of grant proposals also increased significantly more for the CFSP than for the comparison cohort: 0.42 to 2.34 (...) (delta 1.91) versus 0.77 to 1.07 (delta 0.30), P < .01.Institutional investment in mentored research training for junior faculty provided significant grant award gains that began after one year of CFSP participation and persisted over time. The CFSP is a financially sustainable program with effects that are predictable, significant, and enduring.

2016 Academic medicine : journal of the Association of American Medical Colleges

90. Towards Independence: Resubmission Rate of Unfunded National Heart, Lung, and Blood Institute R01 Research Grant Applications among Early Stage Investigators Full Text available with Trip Pro

funded by NHLBI in fiscal years 2010-2012 had percentile scores above but within 10 points of the NHLBI payline, and benefited from the special funding considerations.The only independent predictor of resubmission of NHLBI ESI R01 grant applications was percentile score; applicant demographics and institutional factors were not predictive of resubmission. (...) Towards Independence: Resubmission Rate of Unfunded National Heart, Lung, and Blood Institute R01 Research Grant Applications among Early Stage Investigators The current, budget-driven low rate of National Institutes of Health (NIH) funding for biomedical research has raised concerns about new investigators' ability to become independent scientists and their willingness to persist in efforts to secure funding. The authors sought to determine resubmission rates for unfunded National Heart, Lung

2016 Academic medicine : journal of the Association of American Medical Colleges

91. Size, Accumulation and Performance for Research Grants: Examining the Role of Size for Centres of Excellence Full Text available with Trip Pro

and performance and also how performance for CoEs evolves over the course of grant periods. In terms of dynamics, it appears that performance over the grant period (i.e. 10 years) is falling for the largest CoEs, while it is increasing for those among the smallest half. Overall, multivariate econometric analysis finds evidence that performance is increasing in grant size and over time. In both cases, the relation appears to be non-linear, suggesting that there is a point at which performance peaks. The CoEs (...) Size, Accumulation and Performance for Research Grants: Examining the Role of Size for Centres of Excellence The present paper examines the relation between size, accumulation and performance for research grants, where we examine the relation between grant size for Centres of Excellence (CoE) funded by the Danish National Research Foundation (DNRF) and various ex post research performance measures, including impact and shares of highly cited articles. We examine both the relation between size

2016 PloS one

92. NIH peer review percentile scores are poorly predictive of grant productivity Full Text available with Trip Pro

NIH peer review percentile scores are poorly predictive of grant productivity Peer review is widely used to assess grant applications so that the highest ranked applications can be funded. A number of studies have questioned the ability of peer review panels to predict the productivity of applications, but a recent analysis of grants funded by the National Institutes of Health (NIH) in the US found that the percentile scores awarded by peer review panels correlated with productivity as measured (...) by citations of grant-supported publications. Here, based on a re-analysis of these data for the 102,740 funded grants with percentile scores of 20 or better, we report that these percentile scores are a poor discriminator of productivity. This underscores the limitations of peer review as a means of assessing grant applications in an era when typical success rates are often as low as about 10%.

2016 eLife

93. Biases in grant proposal success rates, funding rates and award sizes affect the geographical distribution of funding for biomedical research Full Text available with Trip Pro

Biases in grant proposal success rates, funding rates and award sizes affect the geographical distribution of funding for biomedical research The ability of the United States to most efficiently make breakthroughs on the biology, diagnosis and treatment of human diseases requires that physicians and scientists in each state have equal access to federal research grants and grant dollars. However, despite legislative and administrative efforts to ensure equal access, the majority of funding (...) for biomedical research is concentrated in a minority of states. To gain insight into the causes of such disparity, funding metrics were examined for all NIH research project grants (RPGs) from 2004 to 2013. State-by-state differences in per application success rates, per investigator funding rates, and average award size each contributed significantly to vast disparities (greater than 100-fold range) in per capita RPG funding to individual states. To the extent tested, there was no significant association

2016 PeerJ

94. Evidence-Based Tele-Emergency Network Grant Program

, MPH University of California, Davis More Information Go to Study Data/Documents: Any study documents may be requested directly from Jamie Kissee at jkissee@ucdavis.edu Layout table for additonal information Responsible Party: University of California, Davis ClinicalTrials.gov Identifier: Other Study ID Numbers: 678668 G01RH27872 ( Other Grant/Funding Number: HRSA ) First Posted: August 24, 2016 Last Update Posted: August 29, 2018 Last Verified: August 2018 Individual Participant Data (IPD) Sharing (...) Evidence-Based Tele-Emergency Network Grant Program Evidence-Based Tele-Emergency Network Grant Program - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Evidence-Based Tele-Emergency Network Grant Program

2016 Clinical Trials

95. Recovery Roadmap Phase II Small Business Innovation Research Grant

Roadmap prototype was developed and tested by the Center for Social Innovation (C4), in partnership with Yale University's Program for Recovery and Community Health (PRCH), under a Phase I Small Business Innovative Research (SBIR) grant funded by the National Institute of Mental Health (NIMH) (1R43MH100712). Phase II will refine the prototype Roadmap to streamline content, provide additional handouts and exercises for providers and clients to complete together, expand the audio/video vignettes (...) Recovery Roadmap Phase II Small Business Innovation Research Grant Recovery Roadmap Phase II Small Business Innovation Research Grant - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Recovery Roadmap Phase

2016 Clinical Trials

96. Medical communication companies and industry grants. Full Text available with Trip Pro

Medical communication companies and industry grants. Medical communication companies (MCCs) are among the most significant health care stakeholders, supported mainly by drug and device companies. How MCCs share or protect physicians' personal data requires greater transparency.To explore the financial relationships between MCCs and drug and device companies, to describe the characteristics of the large MCCs, and to explore whether they accurately represent themselves to physicians.We combined (...) data from the 2010 grant registries of 14 pharmaceutical and device companies; grouped recipients into categories such as MCCs, academic medical centers, disease-targeted advocacy organizations, and professional associations; and created a master list of 19,272 grants.Determine the distribution of funds from drug and device companies to various entities and assess the characteristics of large MCCs.Of the 6493 recipients of more than $657 million grant awards from drug and device companies, 18

2013 JAMA

97. How my skepticism brought about a culture change in how our residency functions

How my skepticism brought about a culture change in how our residency functions How my skepticism brought about a culture change in how our residency functions How my skepticism brought about a culture change in how our residency functions | | January 30, 2018 64 Shares “No one can know what you’re doing here.” The resident across the table from me made this clear the moment we sat down. We were in her hospital’s cafeteria, talking discreetly at her request with the union coordinator (...) in economics, labor, and history, I soon came to realize that the very conditions underlying the place of resident physicians in the medical system grant us little power or agency and leave us vulnerable to exploitation. The typical resident enters postgraduate training with hundreds of thousands of dollars in debt, making it financially impossible to quit the field and enter into another profession. For resident physicians from outside the United States, their ability to remain in this country legally

2018 KevinMD blog

98. Outcomes of Mentored, Grant-Funded Fellowship Training in Hemostasis/Thrombosis: Findings from a Nested Case-Control Survey Study Full Text available with Trip Pro

Outcomes of Mentored, Grant-Funded Fellowship Training in Hemostasis/Thrombosis: Findings from a Nested Case-Control Survey Study Successful strategies by which to effectively recruit and retain academic subspecialists in benign haematology have not been established. To evaluate the effectiveness of a grant-funded, mentored fellowship with respect to retention and early career goals in haemostasis/thrombosis, we sought to compare outcomes for graduates of a grant-funded, mentored fellowship (...) (range) percent time spent in benign haematology postfellowship was 98% (70-100%) for cases vs. 0% (0-20%) for controls. Time spent in research was significantly greater among cases than controls (median 80% [range: 42-90%] vs. 55% [10-80%], respectively; P = 0.01). By years 3-4 postfellowship, median annual number of peer-reviewed publications was higher for cases than controls (3.5 vs. 1.0; P = 0.01). Cases were also more successful in grant funding (including K-awards). These data suggest

2011 Haemophilia

99. The Impact of Research Grant Funding on Scientific Productivity Full Text available with Trip Pro

The Impact of Research Grant Funding on Scientific Productivity In this paper, we estimate the impact of receiving an NIH grant on subsequent publications and citations. Our sample consists of all applications (unsuccessful as well as successful) to the NIH from 1980 to 2000 for standard research grants (R01s). Both OLS and IV estimates show that receipt of an NIH research grant (worth roughly $1.7 million) leads to only one additional publication over the next five years, which corresponds (...) to a 7 percent increase. The limited impact of NIH grants is consistent with a model in which the market for research funding is competitive, so that the loss of an NIH grant simply causes researchers to shift to another source of funding.

2011 Journal of Public Economics

100. Early career academic productivity among emergency physicians with r01 grant funding. Full Text available with Trip Pro

Early career academic productivity among emergency physicians with r01 grant funding. The objective was to describe the early academic career activities of emergency physician (EP) scientists with recent Research Project Grant Program (R01) grant funding from the National Institutes of Health (NIH).The curricula vitae of all EP scientists in the United States currently funded by the NIH were analyzed for evidence of advanced research training and frequency and type of publication and grant (...) writing. Each investigator was surveyed for demographic features and estimation of protected time during their early career development.Eighteen investigators were identified. The median length of time from completion of residency to receipt of their first R01 grant was 11 years (interquartile range [IQR] = 11 to 15 years), and the median age of investigators at the time of this award was 43 years (IQR = 39 to 47 years). At the time of their award, researchers were publishing five peer-reviewed

2011 Academic Emergency Medicine

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