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41. Pyelonephritis (acute): antimicrobial prescribing

is it for? 4 Recommendations 5 1.1 Managing acute pyelonephritis 5 1.2 Self-care 7 1.3 Choice of antibiotic 7 Summary of the evidence 13 Self-care 13 Antibiotics 13 Choice of antibiotic 14 Antibiotic course length 21 Antibiotic dose frequency 23 Antibiotic route of administration 23 Other considerations 25 Medicines adherence 25 Resource implications 25 Pyelonephritis (acute): antimicrobial prescribing (NG111) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms (...) -and- conditions#notice-of-rights). Page 3 of 26This guideline should be read in conjunction with NG109, NG112 and CG54. Ov Overview erview This guideline sets out an antimicrobial prescribing strategy for acute pyelonephritis (upper urinary tract infection) in children, young people and adults who do not have a catheter. It aims to optimise antibiotic use and reduce antibiotic resistance. See a 3-page visual summary of the recommendations, including a table to support prescribing decisions. NICE has also

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

42. Urinary tract infection (recurrent): antimicrobial prescribing

a catheter. It aims to optimise antibiotic use and reduce antibiotic resistance. See a 2-page visual summary of the recommendations, including a table to support prescribing decisions. NICE has also produced a guideline on antimicrobial stewardship: systems and processes for effective antimicrobial medicine use. Who is it for? Health professionals People with recurrent urinary tract infection, their families and carers Urinary tract infection (recurrent): antimicrobial prescribing (NG112) © NICE 2019 (...) and over people with recurrent upper UTI people with recurrent lower UTI when the underlying cause is unknown pregnant women children and young people under 16 years in line with the NICE guideline on urinary tract infection in under 16s people with suspected cancer in line with the NICE guideline on suspected cancer: recognition and referral. See the evidence and committee discussion on antibiotic prophylaxis. Urinary tract infection (recurrent): antimicrobial prescribing (NG112) © NICE 2019. All

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

43. Urinary tract infection (lower): antimicrobial prescribing

of 35Contents Contents Overview 4 Who is it for? 4 Recommendations 5 1.1 Managing lower urinary tract infection 5 1.2 Managing asymptomatic bacteriuria 8 1.3 Self-care 9 1.4 Choice of antibiotic 9 Summary of the evidence 15 Self-care 15 Antibiotics 16 Choice of antibiotic 23 Antibiotic course length 29 Other considerations 34 Medicines adherence 34 Resource implications 34 Update information 35 Urinary tract infection (lower): antimicrobial prescribing (NG109) © NICE 2019. All rights reserved. Subject (...) to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 3 of 35This guideline should be read in conjunction with CG54, NG111 and NG112. Ov Overview erview This guideline sets out an antimicrobial prescribing strategy for lower urinary tract infection (also called cystitis) in children, young people and adults who do not have a catheter. It aims to optimise antibiotic use and reduce antibiotic resistance. See a 3-page visual summary of the recommendations, including

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

44. Sore throat (acute): antimicrobial prescribing

Recommendations 5 1.1 Managing acute sore throat 5 1.2 Self-care 7 1.3 Choice of antibiotic 8 Summary of the evidence 10 Self-care 10 Corticosteroids 12 No antibiotic 12 Back-up antibiotics 14 Identifying people more likely to benefit from antibiotics 14 Antibiotic choice 18 Antibiotic course length 20 Other considerations 22 Medicines adherence 22 Resource implications 22 T erms used in the guideline 23 FeverPAIN criteria 23 Centor criteria 23 Sore throat (acute): antimicrobial prescribing (NG84) © NICE 2019 (...) . All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 3 of 24Ov Overview erview This guideline sets out an antimicrobial prescribing strategy for acute sore throat. It aims to limit antibiotic use and reduce antimicrobial resistance. Acute sore throat is often caused by a virus, lasts for about a week, and most people get better without antibiotics. Withholding antibiotics rarely leads to complications. See a 2-page visual summary

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

45. Antimicrobial and Immunomodulatory Therapy in Adult Patients with COVID-19

Antimicrobial and Immunomodulatory Therapy in Adult Patients with COVID-19 British Columbia COVID19 Therapeutics Committee (CTC) Clinical Practice Guidance for Antimicrobial and Immunomodulatory Therapy in Adult Patients with COVID-19 SEVERITY OF ILLNESS ANTIVIRAL THERAPY ANTIBACTERIAL THERAPY IMMUNOMODULATORY THERAPY Critically Ill Patients Hospitalized, ICU-based Patients requiring ventilatory and/or circulatory support; also includes patients requiring high-flow nasal cannula, or higher (...) for DVT prophylaxis Chloroquine or hydroxychloroquine (with or without azithromycin) is not recommended outside of approved clinical trials or where other indications would justify its use Lopinavir/ritonavir is not recommended outside of approved clinical trials Remdesivir* is not recommended outside of approved clinical trials Antibacterial therapy is not routinely recommended outside of approved clinical trials or where other indications would justify its use (eg. suspected bacterial co-infection

2020 Covid-19 Ad hoc guidelines

46. Antibiotic Therapy in Preterm Premature Rupture of the Membranes

Antibiotic Therapy in Preterm Premature Rupture of the Membranes No. 233-Antibiotic Therapy in Preterm Premature Rupture of the Membranes - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 39, Issue 9, Pages e207–e212 No. 233-Antibiotic Therapy in Preterm Premature Rupture of the Membranes x Mark H. Yudin , MD Toronto, ON x Julie van Schalkwyk , MD Vancouver, BC x Nancy Van Eyk , MD Halifax, NS No. 233, September 2017 (...) DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. Abstract Objective To review the evidence and provide recommendations on the use of antibiotics in preterm premature rupture of the membranes (PPROM). Outcomes Outcomes evaluated include the effect of antibiotic treatment on maternal infection, chorioamnionitis, and neonatal morbidity and mortality. Evidence Published literature was retrieved through searches of Medline, EMBASE, CINAHL

2017 Society of Obstetricians and Gynaecologists of Canada

47. Antibiotic Prophylaxis in Obstetric Procedures

Antibiotic Prophylaxis in Obstetric Procedures No. 247-Antibiotic Prophylaxis in Obstetric Procedures - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 39, Issue 9, Pages e293–e299 No. 247-Antibiotic Prophylaxis in Obstetric Procedures x Julie van Schalkwyk , MD Vancouver, BC x Nancy Van Eyk , MD Halifax, NS No. 247, September 2017 DOI: To view the full text, please login as a subscribed user or . Click to view the full (...) text on ScienceDirect. Abstract Objective To review the evidence and provide recommendations on antibiotic prophylaxis for obstetrical procedures. Outcomes Outcomes evaluated include need and effectiveness of antibiotics to prevent infections in obstetrical procedures. Evidence Published literature was retrieved through searches of Medline and The Cochrane Library on the topic of antibiotic prophylaxis in obstetrical procedures. Results were restricted to systematic reviews, randomized controlled

2017 Society of Obstetricians and Gynaecologists of Canada

48. Antimicrobial stewardship: Systems and processes for effective antimicrobial medicine use within human health and healthcare in New Zealand

and Contextualisation Group (GRCG) for each guideline. The GRCG will carefully consider the NICE guideline recommendations, taking into account the differences between the UK and New Zealand health care systems to produce a guideline that is relevant to those delivering and managing care in New Zealand. The development of a profusion of antimicrobial medicines since the middle of the twentieth century has been one of the greatest advances of medical science. Antibiotic therapy has reduced the mortality (...) ‘antimicrobial resistance’ is defined as the ‘loss of effectiveness of any anti infective medicine, including antiviral, antifungal, antibacterial and antiparasitic medicines’. Antimicrobials and antimicrobial medicines The term ‘antimicrobials’ and ‘antimicrobial medicines’ includes all anti infective therapies, (antiviral, antifungal, antibacterial and antiparasitic medicines) and all formulations (oral, parenteral and topical agents). Organisations The term ‘organisations’ (also known as the ‘service

2017 Best Practice Advocacy Centre New Zealand

49. Antibiotic selection in the treatment of acute invasive infections by Pseudomonas aeruginosa: Guidelines by the Spanish Society of Chemotherapy Full Text available with Trip Pro

an extraordinary ability to develop resistance to nearly all available antimicrobials through selection of mutations. The progressive increase in resistance rates in P. aeruginosa has led to the emergence of strains which, based on their degree of resistance to common antibiotics, have been defined as multidrug resistant, extended-resistant and panresistant strains. These strains are increasingly disseminated worldwide, progressively complicating the treatment of P. aeruginosa infections. In this scenario (...) . . Pseudomonas aeruginosa Bacteremia: Risk Factors for Mortality and Influence of Delayed Receipt of Effective Antimicrobial Therapy on Clinical Outcome. Clin Infect Dis 2003; 37(6):745-751. DOI: 10.1086/377200 - - Siegman-Igra Y, Ravona R, Primerman H, Giladi M. Pseudomonas aeruginosa bacteremia: an analysis of 123 episodes, with particular emphasis on the effect of antibiotic therapy. Int J Infect Dis 1998; 2(4):211-215. - Show all 237 references Publication types Review Actions MeSH terms Anti-Bacterial

2018 Spanish Clinical Guidelines

50. Preoperative Antibiotics and Surgical Site Infection in Breast Surgery

Preoperative Antibiotics and Surgical Site Infection in Breast Surgery - Official Statement - Consensus Guideline on Preoperative Antibiotics and Surgical Site Infection in Breast Surgery Purpose To outline recommendations for reducing and treating surgical site infections (SSIs). Associated ASBrS Guidelines or Quality Measures 1. This document replaces the previous ASBrS Statement of Position Statement on Antibiotics and Surgical Site Infection. 2. Quality Measure: Surgical Site Infection (...) and Cellulitis After Breast and/or Axillary Surgery Methods Literature review inclusive of recent randomized controlled trials evaluating the indications for and use of antibiotics to reduce and treat SSIs for patients undergoing breast surgery for both benign and malignant disease. This is not a complete systematic review but a comprehensive review of the modern literature on this subject. The ASBrS Research Committee developed a consensus document, which was reviewed and approved by the ASBrS Board

2017 American Society of Breast Surgeons

51. Infectious Diseases Society of America Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections

, antimicrobial resistant pathogens caused more than 2.8 million infections and over 35,000 deaths annually in the United States from 2012 through 2017, according to the 2019 Centers for Disease Control and Prevention (CDC) Antibiotic Resistant Threats Report [2]. The selection of effective antibiotics for the treatment of infections by resistant pathogens is challenging [3]. Although there has been an increase in the availability of novel antibiotics to combat resistant infections in recent years [3 (...) will be disseminated on multiple platforms and updated as new data emerge. Treatment of antimicrobial resistant Gram-negative bacterial infections was chosen as the initial topic for a guidance document. The overarching goal of this guidance document is to assist clinicians – including those with and without infectious diseases expertise – in selecting antibiotic therapy for infections caused by ESBL-E, CRE, and DTR- P. aeruginosa . Future iterations of this document will address other resistant pathogens

2020 Infectious Diseases Society of America

52. Best Practice Statement: Antimicrobial stewardship strategies for wound management

Best Practice Statement: Antimicrobial stewardship strategies for wound management

2021 Wounds UK

58. Rosacea : Oral antibiotics

Rosacea : Oral antibiotics Oral antibiotics | Prescribing information | Rosacea | CKS | NICE Search CKS… Menu Oral antibiotics Rosacea : Oral antibiotics Last revised in June 2020 Oral antibiotics Doxycycline Contraindications and cautions Do not prescribe doxycycline to people: Who are pregnant or breastfeeding women — tetracyclines are deposited in the teeth and growing bones of the unborn or developing child, which can result in discolouration of teeth and occasionally dental hypoplasia (...) : Dyspnoea, hypotension, peripheral oedema, tachycardia (common). Gastrointestinal disturbances, such as nausea, vomiting, and diarrhoea (uncommon). Antibiotic-associated colitis, anxiety, arthralgia, flushing, increased intracranial pressure with papilloedema, myalgia, severe skin reactions, skin hyperpigmentation (long-term use), tinnitus, vision disorders (rare). Stop treatment and seek medical advice if the person develops severe headache and/or visual disturbance that may suggest benign intracranial

2016 NICE Clinical Knowledge Summaries

59. Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults: Advice for High-Value Care From the American College of Physicians and the Centers for Disease Control and Prevention Full Text available with Trip Pro

Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults: Advice for High-Value Care From the American College of Physicians and the Centers for Disease Control and Prevention Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults | Annals of Internal Medicine | American College of Physicians '); } Sign in below to access your subscription for full content INDIVIDUAL SIGN IN | You will be directed to acponline.org to register and create your Annals account (...) INSTITUTIONAL SIGN IN | | Subscribe to Annals of Internal Medicine . You will be directed to acponline.org to complete your purchase. Search Clinical Guidelines | 15 March 2016 Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults: Advice for High-Value Care From the American College of Physicians and the Centers for Disease Control and Prevention Free Aaron M. Harris, MD, MPH; Lauri A. Hicks, DO; Amir Qaseem, MD, PhD, MHA; for the High Value Care Task Force of the American College

2016 American College of Physicians

60. Implementing an Antibiotic Stewardship Program

Implementing an Antibiotic Stewardship Program Practice Guidelines Search Search Practice Guidelines Practice guidelines are systematically developed statements to assist practitioners and patients in making decisions about appropriate health care for specific clinical circumstances. Attributes of good guidelines include validity, reliability, reproducibility, clinical applicability, clinical flexibility, clarity, multidisciplinary process, review of evidence, and documentation. [Institute

2016 Infectious Diseases Society of America

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