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61. Management of Stroke in Neonates and Children

presented as neonates and 44 whose strokes were discovered later. Seventy-six children (68%) exhibited cerebral palsy, and 55 of these individuals had at least 1 additional disability; 45 (59%) experienced cognitive or speech impairment, and 36 (47%) had epilepsy. Detailed neuropsychological testing often documents cognitive dysfunction, especially related to attention and executive function. Such functional deficits are more likely to occur in individuals with a larger infarction, with comorbid (...) that among highly selected adults with AIS and large vessel occlusion, thrombectomy improves 90-day survival without disability over standard medical therapy. A 2016 pooled analysis by Goyal et al of the 1287 adult stroke patients from the 5 endovascular thrombectomy clinical trials published by 2015 demonstrated robust clinical benefits for thrombectomy across a broad spectrum of age and initial stroke severity (moderate or severe, with few minor strokes included) and a number needed to treat of 2.6

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2019 American Heart Association

62. Heart Disease and Stroke Statistics

been cited >20 000 times in the literature. Figure. AHA’s My Life Check – Life’s Simple 7. Seven approaches to staying heart healthy: be active, keep a healthy weight, learn about cholesterol, don’t smoke or use smokeless tobacco, eat a heart-healthy diet, keep blood pressure healthy, and learn about blood sugar and diabetes mellitus. Each annual version of the Statistical Update undergoes revisions to include the newest nationally representative data, add additional relevant published scientific (...) as related deaths and disability-adjusted life-years lost, increased. The majority of global stroke burden is in low-income and middle-income countries. In analyses of 1 165 960 Medicare fee-for-service beneficiaries hospitalized between 2009 and 2013 for ischemic stroke, patients treated at primary stroke centers certified between 2009 and 2013 had lower in-hospital (odds ratio [OR], 0.89; 95% CI, 0.85–0.94), 30-day (hazard ratio, 0.90; 95% CI, 0.89–0.92), and 1-year (hazard ratio, 0.91; 95% CI, 0.90

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2019 American Heart Association

63. United Kingdom National Guideline for the Management of Pelvic Inflammatory Disease (2019 Interim Update)

of mixed race - Irish - White British - Chinese - Other minority groups not listed The highest rates of STI diagnoses at sexual health clinics are found among people of black ethnicity in deprived areas. This is most likely seen as a consequence of a complex interplay of cultural, economic and behavioural factors. Accurate diagnosis and better tolerated treatments should improve the burden of disease in the community Dept of Health Medium Disability - Sensory - Learning disability - Mental health (...) United Kingdom National Guideline for the Management of Pelvic Inflammatory Disease (2019 Interim Update) United Kingdom National Guideline for the Management of Pelvic Inflammatory Disease (2019 Interim Update) Guideline development group: Jonathan Ross (lead author), Michelle Cole, Ceri Evans, Deirdre Lyons, Gillian Dean, Darren Cousins, PPI representative What is new in the 2019 interim update? • the European Medicines Agency has released new guidance highlighting the potential for disabling

2019 British Association for Sexual Health and HIV

64. ESC/ESH Management of Arterial Hypertension

to premature death in 2015, accounting for almost 10 million deaths and over 200 million disability-adjusted life years. Importantly, despite advances in diagnosis and treatment over the past 30 years, the disability-adjusted life years attributable to hypertension have increased by 40% since 1990. SBP ≥140 mmHg accounts for most of the mortality and disability burden (∼70%), and the largest number of SBP-related deaths per year are due to ischaemic heart disease (4.9 million), haemorrhagic stroke (2.0

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2018 European Society of Cardiology

67. Recommendations for the Delivery of Psychosocial Oncology Services in Ontario

with cancer continued on page 1414 | Building the case: why is psychosocial oncology care important? Category Concern Practical • Need for community support (e.g., social work, nursing) • Practical needs (e.g., housing, food, disability aid, transportation, functions of daily living, drug reimbursement, daycare) • Rehabilitation issues (e.g., back-to-work difficulties, changes to home routine and set up) • Employment, school or career concerns, advocacy • Cultural or language issues • Caregiver

2018 Cancer Care Ontario

68. Interpregnancy Care

2014;53:1074–81.e4. Conde-Agudelo A, Rosas-Bermudez A, Norton MH. Birth spacing and risk of autism and other neurodevelopmental disabilities: a systematic review. Pediatrics 2016;137:e20153482. Gunnes N, Suren P, Bresnahan M, Hornig M, Lie KK, Lipkin WI, et al. Interpregnancy interval and risk of autistic disorder. Epidemiology 2013;24:906–12. Ball SJ, Pereira G, Jacoby P, de Klerk N, Stanley FJ. Re-evaluation of link between interpregnancy interval and adverse birth outcomes: retrospective cohort

2019 American College of Obstetricians and Gynecologists

69. Recommendations for the Appropriate Structure, Communication, and Investigation of Tobacco Harm Reduction Claims: An Official ATS Policy Statement

SOCIETY DOCUMENTS e96 American Journal of Respiratory and Critical Care Medicine Volume 198 Number 8 | October 15 2018 especially vulnerable to the negative consequences of nicotine exposure, given the high degree of plasticity during this period. Early exposure potentially alters the normal course of brain growth and development, affecting learning, reasoning, mental health, attention, impulse control, and personality (2, 51–53). Nicotine has a powerful gateway effect on the brain, making (...) the decision-making algorithm. Within-group risk trade-offs are also foreseeable; how do we correctly value avoidance of a known risk if the trade-off involves increasing another? Are disability-adjusted life-years saved an appropriate metric for considering the trade-off? Finally, in a setting of limited resources, investment in one harm reduction strategy may delay or otherwise undermine the development of other, potentially more effective, approaches. Is there an economic metric appropriate

2019 American Thoracic Society

70. Professional Practice Guidelines for the Psychological Practice with Boys and Men

with increasing frequency (Wong & Wester, 2016). GENDER ROLE CONFLICT Gender role conflict (GRC) is defined as problems resulting from adherence to “rigid, sexist, or restrictive gender roles, learned during socialization, that result in personal restriction, devalua- tion, or violation of others or self” (O’Neil, 1990, p. 25). GRC is the most widely studied aspect of masculine gender role strain, and researchers have demonstrated that men experience conflict relat- ed to four domains of the male gender role (...) role strain and gender role conflict (Pleck, 1981, 1995; O’Neil, 2008; O’Neil & Renzulli, 2013), and negatively influence mental health (e.g., O’Neil, 2008, 2013, 2015) and physical health (Courtenay, 2011; Gough & Robertson, 2017). Indeed, boys and men are overrepresented in a variety of psychological and social problems. For example, boys are dispro- portionately represented among schoolchildren with learning dif- ficulties (e.g., lower standardized test scores) and behavior prob- lems (e.g

2019 American Psychological Association

71. Optimal Exercise Programs for Patients With Peripheral Artery Disease: A Scientific Statement From the American Heart Association

the functional independence of patients with PAD. , However, functional impairment and functional decline are present even in people with PAD who are asymptomatic (ie, they have no exertional leg symptoms). , A limited ability to walk represents a disability when people are unable to perform their normal personal, social, and occupational activities. The major goals of treatment in people with claudication and other functional limitations resulting from PAD are to improve walking ability by relieving (...) measures used to assess changes in walking performance in a treadmill exercise test. Of these, PWT or PWD has the greatest reliability. After a treadmill-based SET program, typical changes in PWT, relative to a control group, have been shown to be 3.4 to 4.6 minutes and typical changes in COT have been shown to be 1.65 to 2.2 minutes. , , A limitation of treadmill exercise testing is a learning/placebo effect in which patients with PAD who do not receive an intervention increase their PWD/PWT and COD

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2019 American Gastroenterological Association Institute

72. Management of Acute Compartment Syndrome

. The low volume of casualties coupled with increased deployment frequency has increased concerns regarding medical skill degradation and loss of lessons learned. Thus, the importance of Evidence Based Clinical Practice Guidelines and Appropriate Use Criteria as a readily available resource to the junior forward deployed medical personnel as well as repository of institutional knowledge. This guideline is intended to be used by all qualified and appropriately trained surgeons, physicians and physician (...) , AND CONTRAINDICATIONS All surgical interventions carry the risk of complication and unforeseen consequences. In the case of ACS, it is possible that failure to perform surgery may lead to far greater disability and morbidity. The accurate diagnosis of ACS is the most confounding aspect in treatment and can be affected by patient factors and the experience of the provider. Failure to diagnose ACS can lead to serious systemic illness, limb loss and significant loss of function. With the resultant high index

2019 American Academy of Orthopaedic Surgeons

73. WHO Guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents

COMPARING ANALGESICS FOR CANCER PAIN MANAGEMENT INITIATION & MAINTENANCE AND FOR BREAKTHROUGH CANCER PAIN 137 ANNEX 8: GLOSSARY .. 1386 WHO GUIDELINES FOR THE PHARMACOLOGICAL AND RADIOTHERAPEUTIC MANAGEMENT OF CANCER PAIN IN ADULTS AND ADOLESCENTS WHO GUIDELINES FOR THE PHARMACOLOGICAL AND RADIOTHERAPEUTIC MANAGEMENT OF CANCER PAIN IN ADULTS AND ADOLESCENTS ACKNOWLEDGEMENTS These guidelines were prepared by the WHO Department for Management of Noncommunicable Diseases, Disability, Violence and Injury (...) Bouesseau, Nicolas Clark, Andre Ilbawi, Taskeen Khan, Nicola Magrini and Slim Slama. The WHO Department for Management of Noncommunicable Diseases, Disability, Violence and Injury Prevention would like to thank the members of the Guideline Development Group (GDG) for the commitment, enthusiasm and expertise that they contributed. GDG members: Gauhar Afshan, Zipporah Ali, Chioma Asuzu, Eduardo Bruera, Jim Cleary 1 , Malcolm Dobbin, Kathy Foley, Harmala Gupta, Eric Krakauer 2 , Philip Larkin, Diederik

2019 World Health Organisation Guidelines

74. Incorporating Recognition and Management of Perinatal Depression Into Pediatric Practice

for the child (eg, Back to Sleep) , – ; and difficulty managing chronic health conditions such as asthma or disabilities in the young child. , Families with a parent with depression have been reported to overuse health care and emergency facilities because of somatic complaints and often fall behind on well-child visits and immunizations. Perinatal depression also reduces a mother’s chances of continued breastfeeding because of decreased satisfaction, more reported complications, and lower self-efficacy (...) of the child’s stress responses. Persistent elevation of cortisol can disrupt the developing brain’s architecture in the areas of the amygdala, hippocampus, and prefrontal cortex, affecting learning, memory, and behavioral and emotional adaptation. – Animal studies with rats reveal compelling evidence for a causal relationship between maternal behaviors and stress reactivity in offspring through individual differences in neuronal gene expression transmitted from mother to pup through parenting behaviors

2019 American Academy of Pediatrics

75. Developing a Value Framework for Genetic Diagnosis: Part I A Systematic Review of Outcomes Hierarchies and Measurement Approaches

or models that can be applied and validated for use in genetic diagnoses. KQ2: What can be learned from existing value frameworks in health care? Eighteen relevant articles/documents (six rated Good) were identified. Several sources defined ‘value’ in the health care setting, and in general these were quite consistent. All considered it a ratio of some measure of health benefit, quality or outcomes and financial resources (dollars, costs, money spent). Components of value identified also included (...) Improvement Other initiatives have sought to “transform” health care through the process of quality improvement. Batalden and Davidoff 11 define quality improvement (QI) as: “..the combined and unceasing efforts of everyone – healthcare professionals, patients and their families, researchers, payers, planners and educators – to make the changes that will lead to better patient outcomes (health), better system performance (care) and better professional development (learning).” ACMG Value Review, March 16

2019 American College of Medical Genetics and Genomics

76. Human Papillomavirus (HPV), Cervical Screening and Cervical Cancer

chaotic life events/environments which preclude them from attending a clinic or understanding the importance of regular screening checks. It is equally important to be aware of women who may have learning difficulties or mental health issues, as well as physical disabilities which may require particular consideration. In addition, when caring for women under the age of 25 it is important to convey the rational for not routinely screening, as this is a recurring concern among some young women (DH, 2010 (...) if they have completed a recognised training programme and every registrant has a professional duty to inform their employer if they require training. • In October 2017, the NCSP in England launched a refresher e-learning resource. It has been designed to meet the three-yearly updated requirements of registrants and is free to access for sample takers working in the programme. The resource is available at: www.e-lfh.org.uk/programmes/nhs- screening-programmes • In Northern Ireland the Public Health Agency

2018 Royal College of Nursing

77. Global Vascular Guidelines for patients with chronic limb-threatening ischemia

, and infection who are commonly referred to vascular specialists for evaluation and management. Prior terms, such as “critical” and “severe” limb ischemia, connote specific hemodynamic thresholds and fail to recognize the full spectrum and inter-relatedness of components beyond ischemia that contribute to major limb amputation and long-term disability. This is addressed fully in Section 1 of the guideline. Disease staging in CLTI Improved disease staging is mandatory for designing clinical trials, conducting

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2019 Society for Vascular Surgery

78. Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures

or therapeutic procedure may be minimized, but not completely eliminated, by a careful preprocedure review of the patient’s underlying medical conditions and consideration of how the sedation process might affect or be affected by these conditions: for example, children with developmental disabilities have been shown to have a threefold increased incidence of desaturation compared with children without developmental disabilities. , , Appropriate drug selection for the intended procedure, a clear

2019 American Academy of Pediatrics

79. WHO consolidated guideline on self-care interventions for health: sexual and reproductive health and rights

the following working definition of self-care: Self-care is the ability of individuals, families and communities to promote health, prevent disease, maintain health, and cope with illness and disability with or without the support of a health- care provider. The scope of self-care as described in this definition includes health promotion; disease prevention and control; self-medication; providing care to dependent persons; seeking hospital/specialist/primary care if necessary; and rehabilitation, including (...) and for vulnerable persons (e.g. people with disabilities and mental impairment). This is true for self-care interventions for SRHR, since many people are unable to exercise autonomy over their bodies and are unable to make decisions around sexuality and reproduction. The use and uptake of self-care interventions is organic and the shift in responsibility – between full responsibility of the user and full responsibility of the health-care provider (or somewhere along that continuum) – can also change over time

2019 World Health Organisation Guidelines

80. Recommendations for the Establishment of Stroke Systems of Care: A 2019 Update: A Policy Statement From the American Stroke Association

. The public health implications of an optimized stroke system in the United States and worldwide are profound. A system of care that reduces stroke-related deaths by just 2% to 3% annually would translate into ≈20 000 fewer deaths in the United States alone and ≈400 000 fewer deaths worldwide. Reducing poststroke disability would also improve quality of life, reduce costs, and reduce the burden on patients, their families, third-party payers, and governments. The key components of a modern stroke system (...) , and social influences in a population but also the resources allocated for the provision of public health initiatives. Both cardiovascular disease and stroke are leading causes of death and adult disability. , Thus, they have been the focus of a multitude of national and worldwide primordial and primary prevention causes to reduce the downstream burden of these diseases and the associated lifelong sequelae that affect both patients and families. Stroke systems of care have championed these efforts

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2019 American Heart Association

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