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21. Meta-analysis of aspirin-heparin therapy for un-explained recurrent miscarriage. (Abstract)

Meta-analysis of aspirin-heparin therapy for un-explained recurrent miscarriage. Objective This study was designed to evaluate the efficacy and safety of aspirin-heparin treatment for un-explained recurrent spontaneous abortion (URSA). Methods Literatures reporting the studies on the aspirin-heparin treatment of un-explained recurrent miscarriage with randomized controlled trials (RCTs) were collected from the major publication databases. The live birth rate was used as primary indicator (...) publications of RCTs were included in this study. There were a total of 907 pregnant women with diagnosis of URSA, 367 of them were pooled in the study group with aspirin-heparin therapy and 540 women in the control group with placebo, aspirin or progesterone therapy. Meta-analysis showed that the live birth rate in the study group was significantly different from that in the control group [RR = 1.18, 95% CI (1.00-1.39), P=0.04]. Considering the clinical heterogeneity among the six studies, subgroup

2017 Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih

22. Aspirin Prevention of Colorectal Cancer: Focus on NF-κB Signalling and the Nucleolus Full Text available with Trip Pro

Aspirin Prevention of Colorectal Cancer: Focus on NF-κB Signalling and the Nucleolus Overwhelming evidence indicates that aspirin and related non-steroidal anti-inflammatory drugs (NSAIDs) have anti-tumour activity and the potential to prevent cancer, particularly colorectal cancer. However, the mechanisms underlying this effect remain hypothetical. Dysregulation of the nuclear factor-kappaB (NF-κB) transcription factor is a common event in many cancer types which contributes to tumour

2017 Biomedicines

23. The effects of combined sertraline and aspirin therapy on depression severity among patients with major depressive disorder: A randomized clinical trial Full Text available with Trip Pro

The effects of combined sertraline and aspirin therapy on depression severity among patients with major depressive disorder: A randomized clinical trial Different studies have been conducted to find the best adjuvant therapies for depression management. There are controversies over the effects of aspirin as an adjuvant therapy for depression.To determine the effects of combined sertraline and aspirin therapy on depression severity among patients with major depressive disorder.This randomized (...) clinical trial was conducted at Kargarnejad Psychiatric Hospital in Kashan, Isfahan, Iran, from September 1, 2016 to November 1, 2016. The study participants included 100 patients with major depressive disorder who were assigned to aspirin and placebo groups by the use of computer-generated random numbers. Patients in these groups respectively received sertraline-aspirin and sertraline-placebo for eight consecutive weeks. Patients were prescribed 80 milligrams of aspirin twice a day. Also, sertraline

2017 Electronic physician Controlled trial quality: uncertain

24. Aspirin with or without an antiemetic for acute migraine headaches in adults. Full Text available with Trip Pro

Aspirin with or without an antiemetic for acute migraine headaches in adults. This is an updated version of the original Cochrane review published in Issue 4, 2010 (Kirthi 2010). Migraine is a common, disabling condition and a burden for the individual, health services and society. Many sufferers choose not to, or are unable to, seek professional help and rely on over-the-counter analgesics. Co-therapy with an antiemetic should help to reduce nausea and vomiting commonly associated (...) with migraine headaches.To determine the efficacy and tolerability of aspirin, alone or in combination with an antiemetic, compared to placebo and other active interventions in the treatment of acute migraine headaches in adults.We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, the Oxford Pain Relief Database, ClinicalTrials.gov, and reference lists for studies through 10 March 2010 for the original review and to 31 January 2013 for the update.We included randomised

2013 Cochrane

25. Cost-effectiveness of clopidogrel plus aspirin for stroke prevention in patients with atrial fibrillation in whom warfarin is unsuitable

Cost-effectiveness of clopidogrel plus aspirin for stroke prevention in patients with atrial fibrillation in whom warfarin is unsuitable Cost-effectiveness of clopidogrel plus aspirin for stroke prevention in patients with atrial fibrillation in whom warfarin is unsuitable Cost-effectiveness of clopidogrel plus aspirin for stroke prevention in patients with atrial fibrillation in whom warfarin is unsuitable Coleman CI, Straznitskas AD, Sobieraj DM, Kluger J, Anglade MW Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study assessed the cost-effectiveness of clopidogrel plus aspirin, compared with aspirin alone, for the prevention of stroke in patients with uncomplicated atrial fibrillation. The authors concluded

2013 NHS Economic Evaluation Database.

26. Safety of renal biopsy for patients taking aspirin

Safety of renal biopsy for patients taking aspirin Safety of renal biopsy for patients taking aspirin Safety of renal biopsy for patients taking aspirin Mitchell MD, Berns JS, Rudnick MR, Umscheid CA Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mitchell MD, Berns JS, Rudnick MR, Umscheid CA. Safety of renal biopsy for patients taking (...) aspirin. Philadelphia: Center for Evidence-based Practice (CEP). 2014 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Aspirin; Biopsy; Humans; Nephrectomy; Platelet Aggregation Inhibitors Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence Center for Evidence-based Practice, University of Pennsylvania Health System, 3535 Market St. Suite 50, Philadelphia PA 19104 Email: Cep2

2014 Health Technology Assessment (HTA) Database.

27. Aspirin for VTE prophylaxis in hip and knee replacement surgery

Aspirin for VTE prophylaxis in hip and knee replacement surgery Aspirin for VTE prophylaxis in hip and knee replacement surgery Aspirin for VTE prophylaxis in hip and knee replacement surgery Mitchell MD, Williams K Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mitchell MD, Williams K. Aspirin for VTE prophylaxis in hip and knee replacement surgery (...) . Philadelphia: Center for Evidence-based Practice (CEP). 2014 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirins; Venous Thromboembolism Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence Center for Evidence-based Practice, University of Pennsylvania Health System, 3535 Market St. Suite 50, Philadelphia PA 19104

2014 Health Technology Assessment (HTA) Database.

28. Low-dose aspirin for the prevention of morbidity and mortality from pre-eclampsia: a systematic evidence review for the U.S. preventive services task force

Low-dose aspirin for the prevention of morbidity and mortality from pre-eclampsia: a systematic evidence review for the U.S. preventive services task force Low-dose aspirin for the prevention of morbidity and mortality from pre-eclampsia: a systematic evidence review for the U.S. preventive services task force Low-dose aspirin for the prevention of morbidity and mortality from pre-eclampsia: a systematic evidence review for the U.S. preventive services task force Henderson JT, Whitlock EP (...) , O'Connor E, Senger CA, Thompson JH, Rowland MG Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Henderson JT, Whitlock EP, O'Connor E, Senger CA, Thompson JH, Rowland MG. Low-dose aspirin for the prevention of morbidity and mortality from pre-eclampsia: a systematic evidence review for the U.S. preventive services task force. Rockville: Agency

2014 Health Technology Assessment (HTA) Database.

29. Effects of combined aspirin and clopidogrel therapy on cardiovascular outcomes: a systematic review and meta-analysis

Effects of combined aspirin and clopidogrel therapy on cardiovascular outcomes: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

30. Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials

Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

31. Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials

Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

32. Aspirin for the prevention of cardiovascular events in patients without clinical cardiovascular disease: a meta-analysis of randomized trials

Aspirin for the prevention of cardiovascular events in patients without clinical cardiovascular disease: a meta-analysis of randomized trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

33. Effect of aspirin on vascular and nonvascular outcomes: meta-analysis of randomized controlled trials Full Text available with Trip Pro

Effect of aspirin on vascular and nonvascular outcomes: meta-analysis of randomized controlled trials Effect of aspirin on vascular and nonvascular outcomes: meta-analysis of randomized controlled trials Effect of aspirin on vascular and nonvascular outcomes: meta-analysis of randomized controlled trials Seshasai SR, Wijesuriya S, Sivakumaran R, Nethercott S, Erqou S, Sattar N, Ray KK CRD summary The authors concluded that aspirin as primary prevention reduced risk of non-fatal myocardial (...) infarction, but not the risk of cardiovascular or cancer mortality; bleeding increased with aspirin. Further research was needed and guidelines should be reappraised. The authors’ conclusions reflect the evidence, but the limitations of the review should be borne in mind. Recommendations for further research seem appropriate. Authors' objectives To assess the effects of aspirin for the primary prevention of vascular and non-vascular outcomes. Searching PubMed and the Cochrane Library were searched from

2012 DARE.

34. Cost-effectiveness comparison of breast cancer screening and vascular event primary prevention with aspirin in Wales

Cost-effectiveness comparison of breast cancer screening and vascular event primary prevention with aspirin in Wales Cost-effectiveness comparison of breast cancer screening and vascular event primary prevention with aspirin in Wales Cost-effectiveness comparison of breast cancer screening and vascular event primary prevention with aspirin in Wales Morgan G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study assessed the cost-effectiveness of a health education programme plus aspirin for the primary prevention of vascular events in the general population aged 50 years or older, and compared this with the cost-effectiveness of breast cancer screening. The results supported the implementation of an education programme

2012 NHS Economic Evaluation Database.

35. Cost-effectiveness of aspirin, celecoxib, and calcium chemoprevention for colorectal cancer

Cost-effectiveness of aspirin, celecoxib, and calcium chemoprevention for colorectal cancer Cost-effectiveness of aspirin, celecoxib, and calcium chemoprevention for colorectal cancer Cost-effectiveness of aspirin, celecoxib, and calcium chemoprevention for colorectal cancer Squires H, Tappenden P, Cooper K, Carroll C, Logan R, Hind D Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study assessed the cost-effectiveness of aspirin, celecoxib, or calcium for the prevention of colorectal cancer, with a screening programme, for the general population or those who had undergone colorectal polypectomy. Calcium chemoprevention was likely to be cost-effective after polypectomy, but the evidence was weak. Aspirin could be cost

2012 NHS Economic Evaluation Database.

36. Low-dose aspirin and cancer mortality: a meta-analysis of randomized trials

Low-dose aspirin and cancer mortality: a meta-analysis of randomized trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

37. Bleeding risk in randomized controlled trials comparing warfarin and aspirin: a systematic review and meta-analysis

Bleeding risk in randomized controlled trials comparing warfarin and aspirin: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

38. Is there an association between aspirin dosing and cardiac and bleeding events after treatment of acute coronary syndrome? A systematic review of the literature

Is there an association between aspirin dosing and cardiac and bleeding events after treatment of acute coronary syndrome? A systematic review of the literature Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

39. Aspirin use and breast cancer risk: a meta-analysis

Aspirin use and breast cancer risk: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

40. Aspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer. A systematic review and overview of reviews

Aspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer. A systematic review and overview of reviews Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 Health Technology Assessment (HTA) Database.

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