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1. Acetylsalicylic acid (aspirin) for schizophrenia. (Abstract)

Acetylsalicylic acid (aspirin) for schizophrenia. Schizophrenia is a serious chronic mental illness affecting an estimated 21 million people worldwide and there is increasing evidence linking inflammation in the brain to the pathophysiology of schizophrenia. Antipsychotic drugs are the conventional treatment for people with schizophrenia but are not always fully effective. Acetylsalicylic acid (aspirin) is a non-steroidal anti-inflammatory drug (NSAID) with properties that inhibit (...) the proinflammatory status of the brain. Using aspirin as an adjunct (add-on) treatment to antipsychotics or as a stand-alone treatment could be a novel, relatively inexpensive option for people with schizophrenia.To review the effects of acetylsalicylic acid (aspirin) as adjunct (add-on) or as stand-alone treatment for people with schizophrenia.We searched the Cochrane Schizophrenia Group's Trials Register (last search 8 March 2018) which is based on regular searches of MEDLINE, Embase, PubMed, CINAHL, BIOSIS

2019 Cochrane

2. Combined Argon Laser and Low Dose Acetylsalicylic acid in Treatment of Acute Central Serous Chorioretinopathy. (Abstract)

Combined Argon Laser and Low Dose Acetylsalicylic acid in Treatment of Acute Central Serous Chorioretinopathy. This study was designed to evaluate the efficacy of low-dose of oral acetylsalicylic acid (aspirin) with focal argon laser for the treatment of acute central serous chorioretinopathy (CSCR). In this prospective case-control study, 40 Patients with acute CSCR were classified randomly to two groups; group A with no treatment as the control group and group B with argon Laser in focal (...) treatment once, followed by aspirin, 100 mg per day orally, with follow up period of 12 months by evaluation of visual acuity, and by Optical Coherence Tomography (OCT), every three months for one year. Patients in the second group treated with argon Laser and aspirin showed more clinically significant improvement in both visual acuity and OCT macular thickness by the end of the follow-up period when compared with the observational group. It was concluded that argon Laser with low-dose oral aspirin

2018 Medical hypothesis, discovery & innovation ophthalmology journal Controlled trial quality: uncertain

3. Codeine and acetylsalicylic acid for the management of post-tonsillectomy or adenoidectomy pain: a review of the clinical evidence

Codeine and acetylsalicylic acid for the management of post-tonsillectomy or adenoidectomy pain: a review of the clinical evidence Codeine and acetylsalicylic acid for the management of post-tonsillectomy or adenoidectomy pain: a review of the clinical evidence Codeine and acetylsalicylic acid for the management of post-tonsillectomy or adenoidectomy pain: a review of the clinical evidence CADTH Record Status This is a bibliographic record of a published health technology assessment from (...) a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Codeine and acetylsalicylic acid for the management of post-tonsillectomy or adenoidectomy pain: a review of the clinical evidence. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response - Summary with Critical Appraisal. 2013 Authors' conclusions No relevant literature was identified regarding the risk of bleeding associated with the use of codeine

2014 Health Technology Assessment (HTA) Database.

4. Acetylsalicylic acid for venous thromboembolism prophylaxis: an update of clinical evidence

. Acetylsalicylic acid for venous thromboembolism prophylaxis: an update of clinical evidence. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response. 2014 Authors' conclusions Two systematic reviews, two randomized controlled trials, and two non-randomized studies were identified regarding the use of acetylsalicylic acid (ASA) for venous thromboembolism (VTE) prophylaxis in patients undergoing total hip or total knee replacement. Final publication URL Indexing Status Subject (...) Acetylsalicylic acid for venous thromboembolism prophylaxis: an update of clinical evidence Acetylsalicylic acid for venous thromboembolism prophylaxis: an update of clinical evidence Acetylsalicylic acid for venous thromboembolism prophylaxis: an update of clinical evidence CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH

2014 Health Technology Assessment (HTA) Database.

5. Should acetylsalicylic acid (ASA) therapy for prevention of thromboembolic events be stopped prior to surgical extractions? Full Text available with Trip Pro

Should acetylsalicylic acid (ASA) therapy for prevention of thromboembolic events be stopped prior to surgical extractions? Randomised controlled trial.Patients with coronary artery disease who were receiving 100 mg/day of ASA for the prevention of thromboembolic events, and requiring at least one molar tooth extracted were randomised to either having their ASA therapy suspended for seven days before tooth extraction and restarted the day following the surgical procedure or not having their ASA (...) therapy suspended at any point before or after the procedure. A single dentist who was unaware of the patients' ASA therapy status performed all the extractions.Outcomes were a platelet aggregation test carried out on the day of the operation and the amount of bleeding measured during the intra-operative period.Bleeding was controlled with local haemostatic methods and there were no reported episodes of haemorrhaging during the intra- and post-operative periods. The mean (±SD) volume of bleeding

2013 Evidence-based dentistry Controlled trial quality: uncertain

6. Low doses of acetylsalicylic acid increase risk of gastrointestinal bleeding in a meta-analysis

Low doses of acetylsalicylic acid increase risk of gastrointestinal bleeding in a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2011 DARE.

7. Fluorouracil/salicylic acid (Actikerall®)

Fluorouracil/salicylic acid (Actikerall®) Fluorouracil/salicylic acid (Actikerall®) Fluorouracil/salicylic acid (Actikerall®) All Wales Medicines Strategy Group (AWMSG) Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation All Wales Medicines Strategy Group (AWMSG). Fluorouracil/salicylic acid (Actikerall®) Penarth: All Wales Therapeutics and Toxicology Centre (AWTTC (...) ), secretariat of the All Wales Medicines Strategy Group (AWMSG). AWMSG Secretariat Assessment Report Advice No.1012. 2012 Authors' conclusions Fluorouracil/salicylic acid (Actikerall®) is recommended as an option for use within NHS Wales for the topical treatment of slightly palpable and/or moderately thick hyperkeratotic actinic keratosis (grade I/II) in immunocompetent adult patients. Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Drug Combinations; Fluorouracil; Keratosis

2012 Health Technology Assessment (HTA) Database.

8. Acetylsalicylic acid for venous thromboembolism prophylaxis: a review of clinical evidence, benefits and harms

. No evaluation of the quality of this assessment has been made for the HTA database. Citation Canadian Agency for Drugs and Technologies in Health. Acetylsalicylic acid for venous thromboembolism prophylaxis: a review of clinical evidence, benefits and harms. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). 2011 Authors' conclusions Most of the available evidence from two studies suggested that ASA results in fewer surgical site bleeds and is as effective as vitamin K agonists, low (...) molecular weight heparin, or pentasaccharides for preventing venous thromboembolism after total hip arthroplasty, total knee arthroplasty, and hip fracture surgery. A prospective cohort study suggested that acetylsalicylic acid is less efficacious than low molecular weight heparin in reducing the risk of venous thromboembolism in standard-risk patients Project page URL Indexing Status Subject indexing assigned by CRD MeSH Aspirins; Primary Prevention; Venous Thromboembolism Language Published English

2011 Health Technology Assessment (HTA) Database.

9. Physiological targets of salicylic acid on Artemisia aucheri BOISS as a medicinal and aromatic plant grown under in vitro drought stress Full Text available with Trip Pro

Physiological targets of salicylic acid on Artemisia aucheri BOISS as a medicinal and aromatic plant grown under in vitro drought stress Artemisia aucheri BOISS is a medicinal and aromatic plant, which is endemic to mountainous areas of Iran and surroundings. In this study, we investigated the alleviating effects of salicylic acid (SA) pretreatment (0.01 and 0.1 mM) on A. aucheri under in vitro drought stress induced by 2 and 4% polyethylene glycol (PEG/6000).Plants exposed to PEG stress showed (...) higher levels of H2O2, MDA and electrolyte leakage compared with control. While SA pretreatment decreased these parameters under PEG stress significantly. The activity of CAT, POD, APX, SOD and GR positively changed with PEG and more induction in activity of antioxidant enzymes was observed in SA-pretreated plants under PEG stress. Furthermore, ASA, GSH and their redox ratios (ASC/DHA and GSH/GSSG) enhanced with SA pretreatments. Analysis of our data revealed that MDA, DHA and H2O2 were the best

2016 Botanical studies

10. Acetylsalicylic acid for the prevention of preeclampsia and intra-uterine growth restriction in women with abnormal uterine artery Doppler: a systematic review and meta-analysis

' gestation. Authors' objectives To assess the influence of gestational age at the time of introduction of low-dose acetylsalicylic acid (ASA) on the incidence of pre-eclampsia and intrauterine growth restriction (IUGR) in women at increased risk on the basis of abnormal uterine artery Doppler. Searching MEDLINE, EMBASE and The Cochrane Library were searched without language restrictions from 1965 to 2008. Search terms were reported. Bibliographies of recent two meta-analyses were handsearched (...) Research at the Faculty of Medicine, Université Laval, Québec. Bibliographic details Bujold E, Morency AM, Roberge S, Lacasse Y, Forest JC, Giguere Y. Acetylsalicylic acid for the prevention of preeclampsia and intra-uterine growth restriction in women with abnormal uterine artery Doppler: a systematic review and meta-analysis. Journal of Obstetrics and Gynaecology Canada 2009; 31(9): 818-826 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Aspirin /therapeutic use; Female; Fetal Growth

2009 DARE.

11. Meta-analysis comparing efficacy of benzoyl peroxide, clindamycin, benzoyl peroxide with salicylic acid, and combination benzoyl peroxide/clindamycin in acne

Meta-analysis comparing efficacy of benzoyl peroxide, clindamycin, benzoyl peroxide with salicylic acid, and combination benzoyl peroxide/clindamycin in acne Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2010 DARE.

14. Arthroscopic bone graft procedure combined with arthroscopic subscapularis augmentation (ASA) for recurrent anterior instability with glenoid bone defect: a cadaver study Full Text available with Trip Pro

Arthroscopic bone graft procedure combined with arthroscopic subscapularis augmentation (ASA) for recurrent anterior instability with glenoid bone defect: a cadaver study Glenoid bone loss and capsular deficiency represent critical points of arthroscopic Bankart repair failures. The purpose of this study was to evaluate an all-arthroscopic bone block procedure associated with arthroscopic subscapularis augmentation (ASA) for treating gleno-humeral instability with glenoid bone loss (GBL (...) . No lesions of the surrounding neurovascular structures were observed. No interference was found between the two bone block tunnels and the anchor tunnel used for the tenodesis.This study demonstrated the feasibility and reproducibility of this combined arthroscopic technique (bone block associated with ASA) in the treatment of anterior shoulder instability associated with anterior bone loss and anterior capsular deficiency.

2018 Journal of experimental orthopaedics

16. A new look at low-dose aspirin: Co-administration with tamoxifen in ovulation induction in anovulatory PCOS women. (Abstract)

A new look at low-dose aspirin: Co-administration with tamoxifen in ovulation induction in anovulatory PCOS women. To evaluate the efficacy of co-administration of low-dose aspirin (LDA) and tamoxifen on ovulation rates, endometrial thickness and clinical pregnancy rates in anovulatory PCOS women.A randomized clinical trial was conducted among 188 anovulatory PCOS women at Suez Canal University Hospitals, Ismailia - Egypt. Patients were divided into 2 groups. The study group received a daily

2019 Journal of gynecology obstetrics and human reproduction Controlled trial quality: uncertain

17. Aspirin versus placebo in pregnancies at high risk for preterm pre-eclampsia. Full Text available with Trip Pro

Aspirin versus placebo in pregnancies at high risk for preterm pre-eclampsia. A recent multicentre placebo-controlled trial by Rolnick et al. has indicated that taking 150 mg aspirin daily in women at high risk of pre-eclampsia reduced the incidence of the disease from 4.3% to 1.5% in comparison with placebo. Although the findings of this study are important, a high proportion of women withdrew their consent and not all safety outcomes have been reported. This journal watch article discusses

2018 Obstetric medicine Controlled trial quality: uncertain

18. [EINSTEIN CHOICE: Comparison of rivaroxaban treatment and prophylactic doses with aspirin in the extended treatment of patients with venous thromboembolism]. Full Text available with Trip Pro

[EINSTEIN CHOICE: Comparison of rivaroxaban treatment and prophylactic doses with aspirin in the extended treatment of patients with venous thromboembolism]. Although many patients with venous thromboembolism (VTE) may need extended treatment, efficacy and safety issues of full- or lower-intensity anticoagulation over acetyl salicylic acid (ASA) treatment have remained to be determined. EINSTEIN CHOICE is a randomized, double-blind and phase 3 study, and compared either once-daily rivaroxaban (...) of rivaroxaban and in 1.2% of patients receiving 10 mg of rivaroxaban, in comparison to 4.4% of those receiving aspirin (hazard ratio for 20 mg of rivaroxaban vs. ASA, 0.34; 95% confidence interval [CI] 0.20 to 0.59; hazard ratio for 10 mg of rivaroxaban vs. ASA, 0.26; 95% CI 0.14 to 0.47; P<0.001 for both comparisons). Rates of major bleeding and adverse events were comparable among three treatment groups. In conclusion, in patients with VTE in equipoise for extended anticoagulation, either a treatment dose

2018 Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir Controlled trial quality: predicted high

19. Effect of low dose aspirin and dipyridamole on primary patency of arteriovenous grafts in hemodialysis patients: a randomized double-blind placebo-controlled trial Full Text available with Trip Pro

Effect of low dose aspirin and dipyridamole on primary patency of arteriovenous grafts in hemodialysis patients: a randomized double-blind placebo-controlled trial There is some evidence for the efficacy of antiplatelet therapies in increasing the vascular access patency duration or decreasing the thrombosis of arteriovenous grafts.To determine the effect of low dose aspirin and dipyridamole on primary patency of arteriovenous grafts in hemodialysis patients.This randomized, double-blind (...) , placebo-controlled trial was done at Imam Reza Hospital in Mashhad, Iran from September 10, 2015 to July 05, 2016. Sixty hemodialysis patients, after the placement of a new arteriovenous graft, were divided into three study groups which including; Group 1, who received 80 mg aspirin tablet daily, Group 2 received 80 mg aspirin plus 75 mg dipyridamole daily and Group 3 received placebo daily. Primary unassisted patency was recorded in follow-up until 12 months and the outcomes were analysed using one

2018 Electronic physician Controlled trial quality: predicted high

20. Aspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer: a systematic review and overview of reviews

of Initial Vascular Events ASA acetylsalicylic acid ASCEND A Study of Cardiovascular Events in Diabetes ASPREE Aspirin in Reducing Events in the Elderly ATT Antithrombotic Trialists BDT British Doctors Trial BP blood pressure CARING Chronotherapy with Low-dose Aspirin for Primary Prevention CHD coronary heart disease CI con?dence interval COD cause of death COX cyclo-oxygenase COX-1 cyclo-oxygenase 1 COX-2 cyclo-oxygenase 2 CRC colorectal cancer CRD Centre for Reviews and Dissemination CV cardiovascular (...) Quality assessment of included studies (n=27) 103 Appendix 6 Data extraction 129 Appendix 7 Summaries of included papers and evidence 227 Appendix 8 Revised protocol: 2 September 2012 239 CONTENTS viii NIHR Journals Library www.journalslibrary.nihr.ac.ukList of abbreviations AAA Aspirin for Asymptomatic Atherosclerosis ACCEPT-D Aspirin and Simvastatin Combination for Cardiovascular Events Prevention Trial in Diabetes APLASA antiphospholipid antibody acetylsalicylic acid ARRIVE Aspirin to Reduce Risk

2013 NIHR HTA programme

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