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121. Shorter Versus Longer Duration of Antibiotic Therapy in Patients With Community-Acquired Pneumonia

of antibiotics has been associated with increased risk of antimicrobial resistance, increased adverse events, and overall increase in costs. (2) The international guidelines on the diagnosis and management of adults with CAP are inconsistent with regard to the duration of antibacterial therapy. The guidelines all recommend treating patients for a minimum of 7 days; however, they do not all recommend a maximum duration. Including a maximum duration would contribute to reducing the risk of antibiotic (...) are intended to inform the Ministry of Health and Long-Term Care’s Health System Funding Strategy. For more information on Health Quality Ontario’s Quality-Based Funding initiative, visit www.hqontario.ca. Shorter Versus Longer Duration of Antibiotic Therapy in Patients With Community-Acquired Pneumonia: A Rapid Review. November 2013; pp. 1–20 7 Rapid Review Research Question What is the optimal duration of antibacterial therapy in patients with community-acquired pneumonia (CAP)? Research Methods

2013 Health Quality Ontario

122. Criteria for Switching From Intravenous to Oral Antibiotics in Patients Hospitalized With Community-Acquired Pneumonia

Criteria for Switching From Intravenous to Oral Antibiotics in Patients Hospitalized With Community-Acquired Pneumonia Criteria for Switching From Intravenous to Oral Antibiotics in Patients Hospitalized With Community-Acquired Pneumonia: A Rapid Review. November 2013; pp. 1–23 Criteria for Switching From Intravenous to Oral Antibiotics in Patients Hospitalized With Community- Acquired Pneumonia: A Rapid Review Health Quality Ontario November 2013 Evidence Development and Standards Branch (...) at Health Quality Ontario Criteria for Switching From Intravenous to Oral Antibiotics in Patients Hospitalized With Community-Acquired Pneumonia: A Rapid Review. November 2013; pp. 1–23 2 Suggested Citation This report should be cited as follows: Health Quality Ontario. Criteria for switching from intravenous to oral antibiotics in patients hospitalized with community-acquired pneumonia: a rapid review. Toronto: Health Quality Ontario; 2013 November. 23 p. Available from: http://www.hqontario.ca

2013 Health Quality Ontario

123. Are Short-Term Late-Generation Antibiotics Equivalent to Standard Penicillin Therapy in the Resolution of Symptoms in Acute Strep Throat in Children?

Are Short-Term Late-Generation Antibiotics Equivalent to Standard Penicillin Therapy in the Resolution of Symptoms in Acute Strep Throat in Children? Systematic Review Snapshot TAKE-HOME MESSAGE Although antibiotics are not the best agent for symptomatic management of streptococcal pharyngitis, according to limited data, short-course antibiotics appear to reduce the duration of symptoms more effectively than longer-course therapy. Are Short-Term Late-Generation Antibiotics Equivalent (...) to Standard Penicillin Therapy in the Resolution of Symptoms in Acute Strep Throat in Children? EBEM Commentators Anand Swaminathan, MD, MPH New York University School of Medicine/Bellevue Hospital Center Department of Emergency Medicine New York, NY Jeffrey Hom, MD, MPH Stony Brook University School of Medicine Departments of Pediatrics (Emergency) and Emergency Medicine Stony Brook, NY Results Table 1. Short (3 days) versus standard (7 days) antibiotic course. Symptom Number of Subjects Difference

2013 Annals of Emergency Medicine Systematic Review Snapshots

124. Are Routine Antibiotics Beneficial For Exacerbations of Chronic Obstructive Pulmonary Disease?

Are Routine Antibiotics Beneficial For Exacerbations of Chronic Obstructive Pulmonary Disease? SystematicReviewSnapshot TAKE-HOME MESSAGE Despite some limitations in current evidence, antibiotics appear to be bene?cial for patients with acute exacerbations of chronic obstructive pulmonary disease, particularly those of higher severity. METHODS DATA SOURCES The Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Litera- ture, Allied (...) were ex- cluded. DATA EXTRACTION AND SYNTHESIS Two authors independently screened references and abstracted data. Quality of evidence was de- termined with domain-based and Grading of Recommendations As- sessment, Development and Evalua- tion approaches. Heterogeneity was expressed with the I 2 statistic. Pooled risk ratios, Peto odds ratios, and weighted mean differences were calculated with ?xed-effect models. Are Routine Antibiotics Bene?cial for Exacerbations of Chronic Obstructive Pulmonary

2013 Annals of Emergency Medicine Systematic Review Snapshots

125. Anaphylaxis in Seniors Receiving Intravenous Antibiotics in Long-Term Care: Clinical Evidence and Guidelines

Anaphylaxis in Seniors Receiving Intravenous Antibiotics in Long-Term Care: Clinical Evidence and Guidelines TITLE: Anaphylaxis in Seniors Receiving Intravenous Antibiotics in Long-Term Care: Clinical Evidence and Guidelines DATE: 30 October 2013 RESEARCH QUESTIONS 1. What is the clinical evidence regarding the occurrence of anaphylaxis in seniors receiving IV antibiotics for common acute infections in long-term care? 2. What are the evidence-based the guidelines regarding monitoring (...) and administration of IV antibiotics to seniors with common acute infections in long-term care? KEY MESSAGE No relevant technology assessment reports, systematic reviews, meta-analyses, randomized controlled trials, non-randomized studies, or evidence-based guidelines regarding the occurrence of anaphylaxis in seniors in long term care receiving IV antibiotics or the guidelines for their use were identified. METHODS A limited literature search was conducted on key resources including PubMed, Medline

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

126. The Timing of Prophylactic Antibiotics for Surgery: A Review of the Clinical Evidence

evidence on the appropriate timing of antimicrobial prophylaxis administered pre-operatively. The Timing of Prophylactic Antibiotics for Surgery 2 RESEARCH QUESTION What is the clinical evidence on the administration of antibiotics at 0 to 14 minutes, 15 to 60 minutes, and 61 to 120 minutes prior to incision during surgery? KEY FINDINGS From limited evidence, a trend was seen between timing of prophylactic antibiotic administration and infection risk. There was a lower risk of infection when surgical (...) The Timing of Prophylactic Antibiotics for Surgery: A Review of the Clinical Evidence Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

127. An ESICM systematic review and meta-analysis of procalcitonin-guided antibiotic therapy algorithms in adult critically ill patients

An ESICM systematic review and meta-analysis of procalcitonin-guided antibiotic therapy algorithms in adult critically ill patients PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2013 PedsCCM Evidence-Based Journal Club

128. Antibiotic Prophylaxis for Patients with Cardiac or Orthopedic Implants undergoing Dental Procedures: A Review of the Clinical Effectiveness and Guidelines

assessment fireside: antibiotic prophylaxis and dental treatment in Canada. Journal of Pharmaceutics [Internet]. 2013 [cited 2013 Mar 6];2013(article ID 365635). Available from: http://www.hindawi.com/journals/jph/2013/365635/ 2. Sexton DJ. Antimicrobial prophylaxis for bacterial endocarditis. 2012 Oct 18 [cited 2013 Feb 22]. In: UpToDate [Internet]. Version 20.4. Waltham (MA): UpToDate; 1992 - . Available from: www.uptodate.com Subscription required. 3. Barbari E, Baddour LM. Prevention of prosthetic (...) Antibiotic Prophylaxis for Patients with Cardiac or Orthopedic Implants undergoing Dental Procedures: A Review of the Clinical Effectiveness and Guidelines Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources and a summary of the best evidence on the topic that CADTH

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

129. Prescribing an antibiotic? Pair it with probiotics

Prescribing an antibiotic? Pair it with probiotics Prescribing an antibiotic? Pair it with probiotics Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Prescribing an antibiotic? Pair it with probiotics View/ Open Date 2013-03 Format Metadata Abstract Recommend that patients taking antibiotics also take probiotics (...) , which have been found to be effective both for the prevention and treatment of antibiotic-associated diarrhea (AAD). Stength of recommendation: A: Based on a systematic review and meta-analysis of randomized controlled trials. URI Part of Citation Journal of Family Practice, 62(3) 2013: 148-150. Rights OpenAccess. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. Collections hosted by hosted by

2013 PURLS

130. Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol

Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2013 PedsCCM Evidence-Based Journal Club

131. Are Antibiotics Required for the Treatment of Uncomplicated Diverticulitis?

Are Antibiotics Required for the Treatment of Uncomplicated Diverticulitis? Systematic Review Snapshot TAKE-HOME MESSAGE Limited data (1 randomized trial) suggest that antibiotics may be no better than placebo for the treatment of uncomplicated diverticulitis. More randomized trial data are required to help de?ne the best therapeutic option. AreAntibioticsRequiredfortheTreatmentof Uncomplicated Diverticulitis? EBEM Commentators Casey M. Smolarz, MD Brian Hohertz, MD Rawle A. Seupaul, MD (...) University of Arkansas for Medical Sciences Little Rock, AR Results The search identi?ed 403 potential studies; 3 trials met inclusion criteria for qualitative analysis. One trial comparedantibioticstoplacebo, 2 one compared 2 antibiotic regimens (cefoxitin versus gentamicin-clinda- mycin) to each other, 3 and the last compared a short course of intrave- nousantibioticstoalongercourse(24 to 48 hours vs. 7 days). 4 Two of the 3 trials reported the Cochrane group’s primaryoutcome, andneitherfounda

2013 Annals of Emergency Medicine Systematic Review Snapshots

132. Discontinuation of Contact Precautions for Antibiotic Resistant Organisms: Clinical Evidence and Guidelines

Discontinuation of Contact Precautions for Antibiotic Resistant Organisms: Clinical Evidence and Guidelines Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time (...) of Contact Precautions for Antibiotic Resistant Organisms: Clinical Evidence and Guidelines DATE: 24 January 2013 RESEARCH QUESTIONS 1. What is the clinical evidence on the criteria for discontinuation of contact precautions for adult patients with antibiotic resistant organisms in acute care and continuing care facilities? 2. What are the evidence-based guidelines on the criteria for discontinuation of contact precautions for adult patients with antibiotic resistant organisms in acute care

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

133. Antibiotics for the Prevention of Post-Cesarean Section Complications: Clinical Evidence and Safety

Jan 29];114(4):752-6. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863989 12. Owens SM, Brozanski BS, Meyn LA, Wiesenfeld HC. Antimicrobial prophylaxis for cesarean delivery before skin incision. Obstet Gynecol. 2009 Sep;114(3):573-9. PubMed: PM19701037 13. Kaimal AJ, Zlatnik MG, Cheng YW, Thiet MP, Connatty E, Creedy P, et al. Effect of a change in policy regarding the timing of prophylactic antibiotics on the rate of postcesarean delivery surgical-site infections. Am J Obstet (...) and Gynaecologists of Canada Infectious Diseases Committee. Antibiotic prophylaxis in obstetric procedures. J Obstet Gynaecol Can [Internet]. 2010 Sep [cited 2013 Jan 29];32(9):878-92. Available from: http://www.sogc.org/guidelines/documents/gui247CPG1009E_000.pdf 17. American College of Obstetricians and Gynecologists. Antimicrobial prophylaxis for cesarean delivery: timing of administration. Committee Opinion no. 465. Obstet Gynecol [Internet]. 2010 Sep [cited 2013 Jan 29];116:791-2. Available from: http

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

134. Randomised controlled trial: A fortified follow-up formula for 3?4-year-olds reduces episodes of acute respiratory infection and antibiotic use compared with cow?s milk

Randomised controlled trial: A fortified follow-up formula for 3?4-year-olds reduces episodes of acute respiratory infection and antibiotic use compared with cow?s milk A fortified follow-up formula for 3–4-year-olds reduces episodes of acute respiratory infection and antibiotic use compared with cow’s milk | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn (...) respiratory infection and antibiotic use compared with cow’s milk Article Text Child health Randomised controlled trial A fortified follow-up formula for 3–4-year-olds reduces episodes of acute respiratory infection and antibiotic use compared with cow’s milk Herman T den Dekker 1 , 2 , Liesbeth Duijts 1 , 2 , 3 Statistics from Altmetric.com Commentary on : Li F , Jin X , Liu B , et al . Follow-up formula consumption in 3- to 4-year-olds and respiratory infections: an RCT . Implications for practice

2015 Evidence-Based Nursing

135. Quantitative other: A local public campaign reduces outpatient antibiotic prescribing in Italy Full Text available with Trip Pro

research is needed on the key components of antimicrobial stewardship activities: the effects on antimicrobial resistance, the cost-effectiveness and the sustainability of effect. Context Antimicrobial resistance (AMR) is an important and growing international health threat. Exposure to antibiotics is the primary driver of AMR; therefore, efforts to tackle this problem commonly focus on reducing unnecessary prescribing. Most antibiotic prescribing occurs in primary care, and the majority of prescribing (...) views about antibiotics related to clinician perceptions, management and outcome? A multi-country study in outpatients with acute cough . Smith R , Coast J . The true cost of antimicrobial resistance . Footnotes Competing interests None. Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many

2015 Evidence-Based Nursing

136. Macrolide Antibiotics and Survival in Patients with Acute Lung Injury

Macrolide Antibiotics and Survival in Patients with Acute Lung Injury PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2012 PedsCCM Evidence-Based Journal Club

137. Re-Use of Open tubes of Antibiotic Creams and Ointments: Clinical Evidence, Safety, and Guidelines

Re-Use of Open tubes of Antibiotic Creams and Ointments: Clinical Evidence, Safety, and Guidelines Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid (...) of research or private study only. It may not be copied, posted on a web site, redistributed by email or stored on an electronic system without the prior written permission of CADTH or applicable copyright owner. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions. TITLE: Re-Use of Open tubes of Antibiotic

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

138. Intrapocket Antibiotics to Prevent Infections from Implantable Cardioverter- Defibrillator and Pacemaker for Adult Patients Undergoing Device Insertion: A Review of Clinical Evidence and Comparative Clinical Effectiveness

Antibiotics for Device Implantation 3 REFERENCES SUMMARIZED Health Technology Assessments No literature identified Systematic Reviews and Meta-analyses No literature identified Randomized Controlled Trials No literature identified Non-Randomized Studies 1. Bloom HL, Constantin L, Dan D, De Lurgio DB, El-Chami M, Ganz LI, et al. Implantation success and infection in cardiovascular implantable electronic device procedures utilizing an antibacterial envelope. Pacing Clin Electrophysiol. 2011 Feb;34(2):133-42 (...) Intrapocket Antibiotics to Prevent Infections from Implantable Cardioverter- Defibrillator and Pacemaker for Adult Patients Undergoing Device Insertion: A Review of Clinical Evidence and Comparative Clinical Effectiveness Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

139. Intracameral Antibiotics for the Prevention of Endophthalmitis Post-cataract Surgery: Clinical Effectiveness, Cost-Effectiveness and Guidelines

Intracameral Antibiotics for the Prevention of Endophthalmitis Post-cataract Surgery: Clinical Effectiveness, Cost-Effectiveness and Guidelines Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all (...) and conditions. TITLE: Intracameral Antibiotics for the Prevention of Endophthalmitis Post-cataract Surgery: Clinical Effectiveness, Cost-Effectiveness and Guidelines DATE: 20 March 2012 RESEARCH QUESTIONS 1. What is the clinical effectiveness of intracameral antibiotics for the prevention of endophthalmitis post-cataract surgery? 2. What is the cost-effectiveness of intracameral antibiotics for the prevention of endophthalmitis post-cataract surgery? 3. What are the evidence-based guidelines

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

140. Prophylactic Cefazolin versus Other Antibiotics for the Reduction of Postsurgical Infection: Comparative Clinical Effectiveness

Prophylactic Cefazolin versus Other Antibiotics for the Reduction of Postsurgical Infection: Comparative Clinical Effectiveness Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts (...) . TITLE: Prophylactic Cefazolin versus Other Antibiotics for the Reduction of Postsurgical Infection: Comparative Clinical Effectiveness DATE: 26 January 2012 RESEARCH QUESTION What is the comparative clinical effectiveness of cefazolin versus other antibiotics for the reduction of postsurgical infection? KEY MESSAGE The evidence suggests the effectiveness of cefazolin for the reduction of postsurgical infection may vary depending upon the type of surgery being performed and the clinical condition

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

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