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21. Probiotics to Prevent Antibiotic Associated Diarrhea in Children

Probiotics to Prevent Antibiotic Associated Diarrhea in Children Emergency Medicine > Journal Club > Archive > November 2017 Toggle navigation November 2017 Probiotics to Prevent Antibiotic Associated Diarrhea in Children Vignette You are working in the SLCH ED. An 18-month-old unvaccinated patient has right ear pain and fever for 4 days, along with a runny nose and irritability. You look in her ear and see a bulging red eardrum. You are a superior clinician so you pull out your insufflator (...) and find that the eardrum has limited mobility, especially compared to the other side. with a diagnosis of acute otitis media in hand, you decide to prescribe high-dose amoxicillin for the child, based on the . However, as you start to explain this to the parents, they sound very hesitant because they have had other children who "always" get diarrhea when given antibiotics. They also recently had an elderly relative who was ill due to C. diff and they are scared to give their daughter antibiotics

2018 Washington University Emergency Medicine Journal Club

22. Do antibiotics improve outcomes for patients hospitalized with COPD exacerbations?

Do antibiotics improve outcomes for patients hospitalized with COPD exacerbations? Do antibiotics improve outcomes for patients hospitalized with COPD exacerbations? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Do antibiotics improve outcomes for patients hospitalized with COPD exacerbations? View/ Open Date 2012-09 (...) Format Metadata Abstract Antibiotic use reduced mortality and treatment failure in patients hospitalized with acute exacerbations of chronic obstructive pulmonary disease (COPD) (strength of recommendation [SOR]: A, systematic reviews of randomized controlled trials [RCTs]). Giving antibiotics early to hospitalized patients decreased the need for later ventilation and readmission within 30 days for exacerbation of COPD (SOR: B, a retrospective cohort study). URI Citation Journal of Family Practice

2018 Clinical Inquiries

23. Is Antibiotic Therapy Helpful for Preventing Infection After Acute Stroke? (SRS therapy)

Is Antibiotic Therapy Helpful for Preventing Infection After Acute Stroke? (SRS therapy) Is Antibiotic Therapy Helpful for Preventing Infection After Acute Stroke? TAKE-HOME MESSAGE In patients with acute ischemic or hemorrhagic stroke, prophylactic antibiotics reduce the overall infection rate, but do not reduce the risk of pneumonia, death or dependency. EBEM Commentators Latha Ganti, MD, MBA Department of Clinical Sciences University of Central Florida College of Medicine Orlando, FL Bryan (...) Sleigh, MD Department of Emergency Medicine Mercer University School of Medicine Macon, GA Jestin N. Carlson, MD, MS, and Alan Jones, MD, serve as editors of the SRS series. Editor’s Note: This is a clinical synopsis, a regular feature of the Annals’ Systematic Review Snapshot (SRS) series. The source for this systematic review snapshot is: Vermeij JD, Westendorp WF, Dippel DWJ, et al. Antibiotic therapy for preventing infections in people with acute stroke. Cochrane Database Syst Rev. 2018;1

2018 Annals of Emergency Medicine Systematic Review Snapshots

24. Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis

Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis Michael Gottlieb, MD*; Joshua M. DeMott, PharmD, MSc; Marilyn Hallock, MD, MS; Gary D. Peksa, PharmD *Corresponding Author. E-mail: michaelgottliebmd@gmail.com, Twitter: @MGottliebMD. Study objective: The addition of antibiotics to standard incision and drainage (...) is controversial, with earlier studies demonstrating no signi?cant bene?t. However, 2 large, multicenter trials have recently been published that have challenged the previous literature. The goal of this review was to determine whether systemic antibiotics for abscesses after incision and drainage improve cure rates. Methods: PubMed, the Cumulative Index of Nursing and Allied Health Literature, Scopus, the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials

2018 Annals of Emergency Medicine Systematic Review Snapshots

25. Antibiotics: repeated treatments before the age of two could be a factor in obesity

Antibiotics: repeated treatments before the age of two could be a factor in obesity Prescrire IN ENGLISH - Spotlight ''Antibiotics: repeated treatments before the age of two could be a factor in obesity'', 1 June 2018 {1} {1} {1} | | > > > Antibiotics: repeated treatments before the age of two could be a factor in obesity Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |  (...)  |  Spotlight Antibiotics: repeated treatments before the age of two could be a factor in obesity Antibiotics disrupt the intestinal flora (intestinal microbiota) and could be a factor in weight gain. Prescription of antibiotics for children should not be automatic but should be evaluated on a case-by-case basis. Overweight and obesity are the result of an imbalance between energy intake and energy expenditure and can be associated with various known genetic, hormone, environmental

2018 Prescrire

26. Proposals for a more effective antibiotic policy in Belgium

(BAPCOC) 24 1.1.6 Difficult to obtain significant improvements 24 1.2 RESEARCH QUESTIONS & SCOPE 25 1.3 TERMINOLOGY 25 1.4 METHODOLOGY 26 1.5 STRUCTURE OF THE REPORT 26 2 ANTIBIOTIC USE AND ITS LINK WITH ANTIBACTERIAL RESISTANCE 27 2.1 WHAT IS ANTIMICROBIAL RESISTANCE? 27 2.1.1 Antibacterial resistance, a natural phenomenon 27 2.1.2 How do bacteria become resistant? 27 2.1.3 How does antibiotic resistance spread? 28 2.1.4 Multidrug resistant organisms 28 2.1.1 Resistance in community and healthcare (...) . This document is available on the website of the Belgian Health Care Knowledge Centre. KCE Report 311 Antibiotic policy in Belgium 1 ? TABLE OF CONTENTS LIST OF FIGURES 8 LIST OF TABLES 10 LIST OF ABBREVIATIONS 13 ? SCIENTIFIC REPORT 23 1 INTRODUCTION 23 1.1 SHORT DESCRIPTION OF THE PROBLEM 23 1.1.1 Antibiotic resistance 23 1.1.2 Antibiotic use in Belgium 24 1.1.3 The concept of prudent antimicrobial/antibiotic use 24 1.1.4 One Health approach 24 1.1.5 Belgian Antibiotic Policy Coordination Committee

2019 Belgian Health Care Knowledge Centre

27. Fluoroquinolone antibiotics: new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effects

and tendon rupture report suspected adverse drug reactions to fluoroquinolone antibiotics on the or via the Yellow Card app (download it from the , or ) New restricted indications Fluoroquinolones are antibiotics authorised for serious, life-threatening bacterial infections. As for all antibiotic medicines, consideration should be given to official guidance on the appropriate use of antibacterial agents (see section below on Prescribing guidance). Following an EU-wide review of safety, new restricted (...) Fluoroquinolone antibiotics: new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effects Fluoroquinolone antibiotics: new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effects - GOV.UK GOV.UK uses cookies to make the site simpler. or Search Fluoroquinolone antibiotics: new restrictions and precautions for use due to very rare reports

2019 MHRA Drug Safety Update

28. Antibiotics in Acute Uncomplicated Diverticulitis

Antibiotics in Acute Uncomplicated Diverticulitis Emergency Medicine > Journal Club > Archive > March 2016 Toggle navigation March 2016 Antibiotics in Acute Uncomplicated Diverticulitis Vignette You are halfway through an average weekday shift in EM-2 when you encounter a very pleasant 50-year-old gentleman with abdominal pain. He reports the pain began three days ago and has progressively worsened. It is a dull, moderate pain located in the left lower quadrant with no radiation. He denies (...) check basic labs and order a CT scan of the abdomen and pelvis with IV contrast. His WBC is 14K and his CT reveals uncomplicated sigmoid diverticulitis without perforation of abscess formation. As you are ordering antibiotics, you remember seeing a recent article in suggesting that antibiotics may not actually be necessary to treat diverticulitis. You had previously scoffed at the suggestion and tossed the magazine in the trash, but now wonder if the assertion was based on real science. Aware

2017 Washington University Emergency Medicine Journal Club

29. Maternal and child health: Procalcitonin-guided decision-making results in a significant reduction of antibiotic therapy and hospital stay in neonates with suspected early-onset sepsis

Maternal and child health: Procalcitonin-guided decision-making results in a significant reduction of antibiotic therapy and hospital stay in neonates with suspected early-onset sepsis Procalcitonin-guided decision-making results in a significant reduction of antibiotic therapy and hospital stay in neonates with suspected early-onset sepsis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings (...) in a significant reduction of antibiotic therapy and hospital stay in neonates with suspected early-onset sepsis Article Text Commentary Maternal and child health Procalcitonin-guided decision-making results in a significant reduction of antibiotic therapy and hospital stay in neonates with suspected early-onset sepsis Meret Merker 1 , 2 , Rebekka Bolliger 1 , 2 , Philipp Schuetz 1 , 2 Statistics from Altmetric.com Commentary on : Stocker M, van Herk W, El Helou S, et al . Procalcitonin-guided decision making

2018 Evidence-Based Medicine

30. The Timing of Early Antibiotics and Hospital Mortality in Sepsis

The Timing of Early Antibiotics and Hospital Mortality in Sepsis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2017 PedsCCM Evidence-Based Journal Club

31. Game Changer? How Many Days of Antibiotics is Best for Treating Community Acquired Pneumonia?

Game Changer? How Many Days of Antibiotics is Best for Treating Community Acquired Pneumonia? Game Changer? How Many Days of Antibiotics is Best for Treating Community Acquired Pneumonia? – Clinical Correlations Search Game Changer? How Many Days of Antibiotics is Best for Treating Community Acquired Pneumonia? January 16, 2018 6 min read By Calvin Ngai, MD Peer Reviewed A 71-year-old Caucasian woman with hypertension presented with a 2-day history of productive cough and fever. She was living (...) alone and had no history of any recent hospitalizations. On examination, she was alert and oriented but slightly tachypneic; her lungs were clear to auscultation bilaterally. Laboratory tests were significant for a white blood cell count of 18,000 m L with 89% neutrophils. The chest x-ray showed a right lower lobe infiltrate. She was admitted and started on antibiotics for treatment of community acquired pneumonia (CAP). She improved clinically, and after remaining afebrile for 48 hours, she

2018 Clinical Correlations

32. Are Latino Cultural Beliefs Increasing Antibiotic Resistance in the US?

of the excessive use of antibiotics, as exposure to multiple antibacterial agents provides the selective pressure for the rise and spread of these pathogens. 1 Studies have shown that the overuse of antibiotics is a consequence of the increased worldwide availability of these agents and 1 This issue is particularly relevant in Latin American countries, . 2 Given the increase in the numbers of Latino immigrants, it is important to examine their perceptions of medicine and antibiotic use in order to devise (...) better strategies to control the rise of antimicrobial resistant pathogens—a major global public health problem. Latin American countries have fewer restrictions on the sale of antimicrobial agents, and the existing . 3 This enables the self-diagnosing and self-medicating practices that many members of the Latino community are accustomed to. Furthermore, cultural beliefs and misconceptions regarding the purpose and function of antibiotics play a major role in their misuse among the Latino population

2018 Clinical Correlations

33. Primary care: Trimethoprim is associated with a greater risk of acute kidney injury and hyperkalaemia in older adults compared with other antibiotics used to treat UTIs

Primary care: Trimethoprim is associated with a greater risk of acute kidney injury and hyperkalaemia in older adults compared with other antibiotics used to treat UTIs Trimethoprim is associated with a greater risk of acute kidney injury and hyperkalaemia in older adults compared with other antibiotics used to treat UTIs | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser (...) injury and hyperkalaemia in older adults compared with other antibiotics used to treat UTIs Article Text Commentary Primary care Trimethoprim is associated with a greater risk of acute kidney injury and hyperkalaemia in older adults compared with other antibiotics used to treat UTIs Oghenekome Gbinigie Statistics from Altmetric.com Commentary on : Crellin E, Mansfield KE, Leyrat C, et al . Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study. BMJ

2018 Evidence-Based Medicine

34. General medicine: Antibiotic prescribing does not decrease complications in adult patients with lower respiratory tract infections

General medicine: Antibiotic prescribing does not decrease complications in adult patients with lower respiratory tract infections Antibiotic prescribing does not decrease complications in adult patients with lower respiratory tract infections | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Antibiotic prescribing does not decrease complications in adult patients with lower respiratory tract infections Article Text Commentary General

2018 Evidence-Based Medicine

35. Topical Antibiotics for Infection Prevention: A Review of the Clinical Effectiveness and Guidelines

Topical Antibiotics for Infection Prevention: A Review of the Clinical Effectiveness and Guidelines Topical Antibiotics for Infection Prevention: A Review of the Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Topical Antibiotics for Infection Prevention: A Review of the Clinical Effectiveness and Guidelines Topical Antibiotics for Infection Prevention: A Review of the Clinical Effectiveness and Guidelines Published on: March 30, 2017 Project Number: RC0854-000 (...) Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of topical antibiotics for patients to prevent skin or wound infection? What are the evidence-based guidelines regarding the use of topical antibiotics for the prevention of skin or wound infection? Key Message Two systematic reviews and one non-randomized study showed that in non-surgical patients, exit site infection rates were statistically significantly

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

36. Topical Antibiotics for Infected Dermatitis: A Review of the Clinical Effectiveness and Guidelines

Topical Antibiotics for Infected Dermatitis: A Review of the Clinical Effectiveness and Guidelines Topical Antibiotics for Infected Dermatitis: A Review of the Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Topical Antibiotics for Infected Dermatitis: A Review of the Clinical Effectiveness and Guidelines Topical Antibiotics for Infected Dermatitis: A Review of the Clinical Effectiveness and Guidelines Published on: March 3, 2017 Project Number: RC0852-000 Product (...) Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of topical antibiotics for patients with infected dermatitis? What are the evidence-based guidelines regarding the use of topical antibiotics for the treatment of infected dermatitis? Key Message Evidence to date suggests that topical antibiotics provide no additional benefits when added to other topical treatments in both children and adults with clinically

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

37. Topical Antibiotics for Impetigo: A Review of the Clinical Effectiveness and Guidelines

Topical Antibiotics for Impetigo: A Review of the Clinical Effectiveness and Guidelines Topical Antibiotics for Impetigo: A Review of the Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Topical Antibiotics for Impetigo: A Review of the Clinical Effectiveness and Guidelines Topical Antibiotics for Impetigo: A Review of the Clinical Effectiveness and Guidelines Published on: February 21, 2017 Project Number: RC0851-000 Product Line: Research Type: Drug Report Type (...) : Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of topical antibiotics for patients with impetigo? What are the evidence-based guidelines regarding the use of topical antibiotics for the treatment of impetigo? Key Message The evidence identified in this report supports the clinical efficacy of topical antibiotics, specifically mupirocin and fusidic acid, for the treatment of impetigo. Insufficient evidence was identified to support the clinical efficacy

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

38. Antibiotics for Acute Asthma Exacerbations: Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Antibiotics for Acute Asthma Exacerbations: Clinical Effectiveness, Cost-Effectiveness, and Guidelines Antibiotics for Acute Asthma Exacerbations: Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Antibiotics for Acute Asthma Exacerbations: Clinical Effectiveness, Cost-Effectiveness, and Guidelines Antibiotics for Acute Asthma Exacerbations: Clinical Effectiveness, Cost-Effectiveness, and Guidelines Published on: March 23, 2017 Project Number (...) : RB1076-000 Product Line: Research Type: Drug Report Type: Summary of Abstracts Result type: Report Question What is the clinical effectiveness of antibiotics for acute asthma exacerbations without clear signs of bacterial infection? What is the cost-effectiveness of antibiotics for acute asthma exacerbations without clear signs of bacterial infection? What are the evidence-based guidelines regarding the use of antibiotics for acute asthma exacerbations? Key Message Three randomized-control trials

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

39. Antimicrobial prescribing: ceftolozane with tazobactam for treating hospital-acquired pneumonia, including ventilator-associated pneumonia

for Antimicrobial Utilisation and Resistance (ESPAUR) Report 2018 to 2019 states that monitoring the use of new antibiotics and detecting emerging resistance to these medicines is a crucial component of antimicrobial usage surveillance to inform antimicrobial stewardship activities and preserve treatment effectiveness. Although susceptibility testing for ceftolozane with tazobactam is currently uncommon and selective (following resistance to first- and second-line antibiotics), resistance has nonetheless been (...) ) is Antimicrobial prescribing: ceftolozane with tazobactam for treating hospital-acquired pneumonia, including ventilator-associated pneumonia (ES22) © NICE 2020. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 5 of 6£402.18 (BNF, November 2019). The acquisition costs (excluding VAT) of many other IV antibiotics that are used for HAP and VAP (caused or suspected to be caused by Gram-negative pathogens) are lower than that of ceftolozane

2020 National Institute for Health and Clinical Excellence - Advice

40. Reducing antibiotic resistance

of antibiotic resistance. This year, we're urging people that it's time to take antibiotic resistance seriously. NPS MedicineWise has created a suite of resources you can download, print and share to raise awareness about antibiotic resistance and help preserve the power of antibiotics. Australian Prescriber: Antimicrobial use and resistance in Australia John Turnidge Aust Prescr 2017;40:2-31 Feb 2017 Managing the emergence and increasing resistance to antimicrobials in hospitals and the community has (...) become an urgent national and international problem. As part of a plan to tackle this, Australia is developing a coordinated national program to monitor antimicrobial use and resistance. Sometimes, parents need reassurance rather than antibiotics When their children are unwell, parents and carers often visit their GP for reassurance. They want to check their child doesn’t have a serious illness and have the opportunity to discuss what is worrying them about their child’s cold, cough, earache or sore

2017 National Prescribing Service Limited (Australia)

Evidence-based Synopses

Synopses are typically easily digested, critical commentaries of articles e.g. critically appraised topics.