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241. Randomised controlled trial: Targeted, immediate antibiotics following a positive dipstick test may be the optimal management strategy Full Text available with Trip Pro

Randomised controlled trial: Targeted, immediate antibiotics following a positive dipstick test may be the optimal management strategy Targeted, immediate antibiotics following a positive dipstick test may be the optimal management strategy | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Targeted, immediate antibiotics following a positive dipstick test may be the optimal management strategy Article Text Treatment Randomised controlled

2010 Evidence-Based Medicine

242. Procalcitonin-guided antibiotics in severe sepsis Full Text available with Trip Pro

Procalcitonin-guided antibiotics in severe sepsis Procalcitonin-guided antibiotics in severe sepsis | Critical Care | Full Text Advertisement Menu Search Search all BMC articles Search Menu We'd love your feedback. Please complete this 3 question Table of Contents , Eric B Milbrandt and Lillian L Emlet Critical Care 2008 12 :309 © BioMed Central Ltd 2008 Published: 4 December 2008 Citation Nobre V, Harbarth S, Graf JD, Rohner P, Pugin J: Use of procalcitonin to shorten antibiotic treatment (...) duration in septic patients: a randomized trial. Am J Respir Crit Care Med 2008, 177: 498–505 [ ]. Background The duration of antibiotic therapy in critically ill patients with sepsis can result in antibiotic overuse, increasing the risk of developing bacterial resistance. Procalcitonin (PCT)-guided antibiotic use reduces antibiotic exposure in community-acquired pneumonia. Whether it might also reduce antibiotic exposure in severe sepsis is unknown. Methods Objective To test the hypothesis

2009 Critical Care - EBM Journal Club

243. Clostridium difficile: moving beyond antimicrobial therapy Full Text available with Trip Pro

Clostridium difficile: moving beyond antimicrobial therapy Clostridium difficile: moving beyond antimicrobial therapy | Critical Care | Full Text Advertisement Menu Search Search all BMC articles Search Menu We'd love your feedback. Please complete this 3 question Table of Contents , and John A Kellum Critical Care 2010 14 :320 © BioMed Central Ltd 2010 Published: 16 September 2010 Citation Lowy I, Molrine DC, Leav BA, Blair BM, Baxter R, Gerding DN, Nichol G, Thomas WD Jr, Leney M, Sloan S (...) . difficile infection, recurrence rates were 7% and 38%, respectively ( P = 0.006). The mean duration of the initial hospitalization for inpatients did not differ significantly between the antibody and placebo groups (9.5 and 9.4 days, respectively). At least one serious adverse event was reported by 18 patients in the antibody group and by 28 patients in the placebo group ( P = 0.09). Conclusions The addition of monoclonal antibodies against C. difficile toxins to antibiotic agents significantly reduced

2010 Critical Care - EBM Journal Club

244. Systematic review: Preventive antibiotics reduce infections but not mortality in adults with acute stroke

Systematic review: Preventive antibiotics reduce infections but not mortality in adults with acute stroke Preventive antibiotics reduce infections but not mortality in adults with acute stroke | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Preventive antibiotics reduce infections but not mortality in adults with acute stroke Article Text Therapeutics Systematic review Preventive antibiotics reduce infections but not mortality in adults

2010 Evidence-Based Nursing

245. Randomised controlled trial: Interactive booklet reduces antibiotic prescribing for respiratory tract infections in children, but not parent satisfaction Full Text available with Trip Pro

Randomised controlled trial: Interactive booklet reduces antibiotic prescribing for respiratory tract infections in children, but not parent satisfaction Interactive booklet reduces antibiotic prescribing for respiratory tract infections in children, but not parent satisfaction | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies (...) , please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Interactive booklet reduces antibiotic prescribing for respiratory tract infections in children, but not parent

2010 Evidence-Based Nursing

246. Review: quality improvement interventions reduce unnecessary prescription of antibiotics for outpatients

Review: quality improvement interventions reduce unnecessary prescription of antibiotics for outpatients Review: quality improvement interventions reduce unnecessary prescription of antibiotics for outpatientsCommentary | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: quality improvement interventions reduce unnecessary prescription of antibiotics for outpatientsCommentary Article Text Quality improvement Review: quality improvement

2010 Evidence-Based Nursing

247. Randomised controlled trial: Small study finds that hydrophilic catheters decrease use of antibiotics to treat UTI in people with spinal cord injury who use self-intermittent catheterisation compared with non-coated catheters

Randomised controlled trial: Small study finds that hydrophilic catheters decrease use of antibiotics to treat UTI in people with spinal cord injury who use self-intermittent catheterisation compared with non-coated catheters Small study finds that hydrophilic catheters decrease use of antibiotics to treat UTI in people with spinal cord injury who use self-intermittent catheterisation compared with non-coated catheters | Evidence-Based Nursing We use cookies to improve our service and to tailor (...) name or password? You are here Small study finds that hydrophilic catheters decrease use of antibiotics to treat UTI in people with spinal cord injury who use self-intermittent catheterisation compared with non-coated catheters Article Text Therapeutics Randomised controlled trial Small study finds that hydrophilic catheters decrease use of antibiotics to treat UTI in people with spinal cord injury who use self-intermittent catheterisation compared with non-coated catheters Katherine N Moore 1

2010 Evidence-Based Nursing

248. Role of antibiotic line locks in the treatment of infected central venous access devices in children

on the treatment of line colonisation in patients receiving cancer chemotherapy. Papers relating to long term catheter use in non-oncology patients (such as those on haemodialysis, total parenteral nutrition (TPN) and antimicrobial therapy for HIV infection) were excluded as were in vitro studies and the prophylactic use of antibiotic line locks in non-colonised central venous catheters. Search Outcome Seven articles were selected for final analysis. Four articles were found to be of direct relevance (...) Role of antibiotic line locks in the treatment of infected central venous access devices in children BestBets: Role of antibiotic line locks in the treatment of infected central venous access devices in children Role of antibiotic line locks in the treatment of infected central venous access devices in children Report By: P Anoop and M A Anjay - SpR Paediatrics Institution: St George’s Hospital, Blackshaw Road, Tooting, London, James Paget University Hospitals NHS Foundation Trust Date

2009 BestBETS

249. Should additional antibiotics or an iodine washout be given to all patients who suffer an emergency re-sternotomy on the cardiothoracic intensive care unit?

-risk patients are given but neither address emergency re-sternotomy in patients who have recently received these prophylactic antibiotics and may not necessarily have had a sterile reopening. Kriaras et al. published the only paper on patients after cardiac surgery who had open chest CPR on the day of surgery specifically in order to look at the issue of antimicrobial protection. Twelve patients had 10% iodine spread around the peri-sternotomy skin and vancomycin 500 mg intravenously was given peri (...) Should additional antibiotics or an iodine washout be given to all patients who suffer an emergency re-sternotomy on the cardiothoracic intensive care unit? BestBets: Should additional antibiotics or an iodine washout be given to all patients who suffer an emergency re-sternotomy on the cardiothoracic intensive care unit? Should additional antibiotics or an iodine washout be given to all patients who suffer an emergency re-sternotomy on the cardiothoracic intensive care unit? Report

2009 BestBETS

250. Antimicrobials effective for bacterial vaginosis in non-pregnant women

Antimicrobials effective for bacterial vaginosis in non-pregnant women PEARLS Practical Evidence About Real Life Situations PEARLS are succinct summaries of Cochrane Systematic Reviews for primary care practitioners. They Antimicrobials effective for bacterial vaginosis in non-pregnant women Clinical question How effective are antimicrobial agents for bacterial vaginosis (BV) in non-pregnant women? Bottom line Clindamycin cream (NNT* 3), clindamycin ovules and tablets, topical metronidazole (...) immunodeficiency virus. Cochrane Systematic Review Oduyebo OO et al. The effects of antimicrobial therapy on bacterial vaginosis in non-pregnant women. Cochrane Reviews 2009, Issue 3. Article No. CD006055. DOI: 10.1002/14651858.CD006055.pub2. This review contains 24 studies involving 4422 participants PEARLS No. 218, November 2009, written by Brian R McAvoy are funded by the New Zealand Guidelines Group. PEARLS provide guidance on whether a treatment is effective or ineffective. PEARLS are prepared

2011 Cochrane PEARLS

251. Inconclusive evidence of ozone’s antimicrobial or disinfectant effects on teeth

Inconclusive evidence of ozone’s antimicrobial or disinfectant effects on teeth Inconclusive evidence of ozone’s antimicrobial or disinfectant effects on teeth ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take advantage of endorsed, discounted business products Purchase ADA (...) products Access oral-health information for the public and ADA Find-A-Dentist Partnerships and Commissions Learn about ADA CERP recognition, look up CERP recognized CE providers and find CE courses. Explore CODA's role and find accredited schools and programs Learn about the examinations used in licensing dentists and dental hygienists Learn about recognized dental specialties and certifying boards Evidence Education * Associated Topics Inconclusive evidence of ozone’s antimicrobial or disinfectant

2010 ADA Center for Evidence-Based Dentistry

252. Inconclusive evidence of ozone’s antimicrobial or disinfectant effects on teeth

Inconclusive evidence of ozone’s antimicrobial or disinfectant effects on teeth Inconclusive evidence of ozone’s antimicrobial or disinfectant effects on teeth ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take advantage of endorsed, discounted business products Purchase ADA (...) products Access oral-health information for the public and ADA Find-A-Dentist Partnerships and Commissions Learn about ADA CERP recognition, look up CERP recognized CE providers and find CE courses. Explore CODA's role and find accredited schools and programs Learn about the examinations used in licensing dentists and dental hygienists Learn about recognized dental specialties and certifying boards Evidence Education * Associated Topics Inconclusive evidence of ozone’s antimicrobial or disinfectant

2010 ADA Center for Evidence-Based Dentistry

253. Inconclusive evidence of ozone’s antimicrobial or disinfectant effects on teeth

Inconclusive evidence of ozone’s antimicrobial or disinfectant effects on teeth Inconclusive evidence of ozone’s antimicrobial or disinfectant effects on teeth ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take advantage of endorsed, discounted business products Purchase ADA (...) products Access oral-health information for the public and ADA Find-A-Dentist Partnerships and Commissions Learn about ADA CERP recognition, look up CERP recognized CE providers and find CE courses. Explore CODA's role and find accredited schools and programs Learn about the examinations used in licensing dentists and dental hygienists Learn about recognized dental specialties and certifying boards Evidence Education * Associated Topics Inconclusive evidence of ozone’s antimicrobial or disinfectant

2010 ADA Center for Evidence-Based Dentistry

254. Efficacy of Over-The-Counter Antimicrobial Mouthwashes in The Reduction of Recurrent Aphthous Ulcers Symptoms

Efficacy of Over-The-Counter Antimicrobial Mouthwashes in The Reduction of Recurrent Aphthous Ulcers Symptoms UTCAT607, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Listerine is Effective in Treating Recurrent Aphthous Lesions Clinical Question For a patient with recurrent aphthous stomatitis, would treatment with an over-the-counter anti-microbial mouth rinse be more effective at reducing the length of time

2010 UTHSCSA Dental School CAT Library

255. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2009 PedsCCM Evidence-Based Journal Club

256. VULCAN randomised controlled trial: Antimicrobial silver dressings beneath compression for venous ulceration are not cost-effective compared with standard dressings

VULCAN randomised controlled trial: Antimicrobial silver dressings beneath compression for venous ulceration are not cost-effective compared with standard dressings Antimicrobial silver dressings beneath compression for venous ulceration are not cost-effective compared with standard dressings | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we (...) use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Antimicrobial silver dressings beneath compression for venous ulceration are not cost-effective

2010 Evidence-Based Nursing

257. Short course of antibiotics as effective as standard duration for streptococcal pharyngitis in children

Short course of antibiotics as effective as standard duration for streptococcal pharyngitis in children PEARLS Practical Evidence About Real Life Situations PEARLS are succinct summaries of Cochrane Systematic Reviews for primary care practitioners. They Short course of antibiotics as effective as standard duration for streptococcal pharyngitis in children Clinical question How effective is 2 to 6 days of oral antibiotics (short duration) compared to 10 days of oral penicillin (standard (...) duration) in treating children with acute group A beta haemolytic streptococcus (GABHS) pharyngitis? Bottom line Threeto 6 days' treatment with oral antibiotics (macrolides, cephalosporinsor amoxicillin) has comparable efficacy to the standard-duration 10days of oral penicillin in treating children with acute GABHSpharyngitis. Compared to standard-duration treatment, theshort-duration treatment had shorter periods of fever, and throatsoreness, lower risk of early clinical treatment failure

2009 Cochrane PEARLS

258. Insufficient evidence on effectiveness of antibiotics for lactational mastitis

Insufficient evidence on effectiveness of antibiotics for lactational mastitis PEARLS Practical Evidence About Real Life Situations PEARLS are succinct summaries of Cochrane Systematic Reviews for primary care practitioners. They Insufficient evidence on effectiveness of antibiotics for lactational mastitis Clinical question How effective are antibiotics in relieving symptoms of lactational mastitis in breastfeeding women? Bottom line There is insufficient evidence to confirm or refute (...) the effectiveness of antibiotic therapy for the treatment of lactational mastitis. One small trial (n=25) compared amoxicillin with cephradine and found no significant difference between the 2 antibiotics in terms of symptom relief and abscess formation. Another older study compared breast emptying alone as supportive therapy versus antibiotic therapy plus supportive therapy, and no therapy. The findings suggested faster resolution of symptoms for women using antibiotics, although the study design

2009 Cochrane PEARLS

259. Antimicrobial prophylaxis effective for colorectal surgery

Antimicrobial prophylaxis effective for colorectal surgery PEARLS Practical Evidence About Real Life Situations PEARLS are succinct summaries of Cochrane Systematic Reviews for primary care practitioners. They Antimicrobial prophylaxis effective for colorectal surgery Clinical question How effective is antimicrobial prophylaxis for the prevention of postoperative surgical wound infection (SWI) in patients undergoing colorectal surgery? Bottom line Antibiotics delivered orally and intravenously (...) of longer term adverse effects, such as Clostridium difficile pseudomembranous colitis. Context Abdominal SWI in patients having operations on the large intestine occurs in about 40% of patients if antibiotics are not given. This risk can be greatly diminished by the administration of antibiotics prophylactically before surgery. Cochrane Systematic Review Nelson RL et al. Antimicrobial prophylaxis for colorectal surgery. Cochrane Reviews 2009. Issue 1. Article No. CD001181. DOI:10.1002/14651858.CD001181

2009 Cochrane PEARLS

260. Plus Sutures for preventing surgical site infection

bathing with soap, preferably within a day of the planned surgical procedure. Nasal decolonisation is used when Staphylococcus aureus is a likely cause of SSI. In most surgical cases, people are given antibiotics to prevent bacterial infection. Skin at the surgical site is prepared with an antiseptic preparation immediately before the procedure. T o close the wound, section 1.3.20 of NICE's guideline on surgical site infections recommends to consider antimicrobial triclosan-coated sutures. The wound (...) is dressed with an appropriate dressing and changed using aseptic non-touch technique. Sterile saline is used to cleanse the wound up to 48 hours after surgery. If SSI is suspected, an antibiotic is given that covers the likely organisms causing infection in line with NICE's guideline on antimicrobial stewardship: systems and processes for effective antimicrobial medicine use. Population, setting and intended user Population, setting and intended user Plus Sutures are for wound closure in adults

2020 National Institute for Health and Clinical Excellence - Advice

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