Aside from this study (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040429/) is anyone aware of evidence for aerobic exercise as a PREVENTION or TREATMENT for the common cold?
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- Answered 28 Feb 2020 Conflict of interest declaration: None Cochrane published “Exercise versus no exercise for the occurrence, severity and duration of acute respiratory infections” in 2015 . They conclude: “We cannot determine whether exercise is effective at altering the occurrence, severity or duration of acute respiratory infections. One analysis of four trials suggests that the number of days of illness per episode of infection might be reduced by exercise. The small size of the studies, risk of bias and heterogeneous populations trialled all contribute to the uncertainty. Larger studies, with less risk of bias from patient selection, blinding of outcomes assessors, reporting of all outcomes measured and with registration of study protocols, are required to settle the question.” I then went to Google Scholar (GS) to see who had cited this article (to expose newer studies) and GS shows 17 results  of which three look promising: 1 - Meditation or exercise for preventing acute respiratory infection (MEPARI-2): A randomized controlled trial. PLoS One (2018)  which concludes (while acknowledging it might be underpowered!) : “Training in mindfulness meditation or exercise may help protect against ARI illness.” 2 - Physical activity, sleep and risk of respiratory infections: A Swedish cohort study. PLoS One (2018) , concluding: “We did not find any association between physical activity, sleep duration or sleep quality and the occurrence of upper respiratory tract infections in adult Swedish population.” 3 - The impact of exercise training on the lipid peroxidation metabolomic profile and respiratory infection risk in older adults (2018) : “Moderate exercise training, in older adults, compared with no exercise in controls, did not show a difference in the risk of RIs. A pattern of lipid peroxidation was associated with the number of RIs.” I had a look at the MeSH terms and did a fresh search on PubMed for ("Respiratory Tract Infections/epidemiology"[Mesh]) AND "Exercise"[Majr]  which found “Smoking, leisure-time exercise and frequency of self-reported common cold among the general population in northeastern China: a cross-sectional study.”  which concluded: “Passive smoking was associated with a higher risk of having self-reported common cold at least once, while a high frequency of leisure-time exercise was related to a lower risk of reporting more than one episode of the disease in Chinese.” Finally, I searched PubMed and GS for “exercise AND (common cold OR upper respiratory infections)” to look for any newer studies that might have been missed. I found one protocol , but nothing else! References 1) https://www.ncbi.nlm.nih.gov/pubmed/26077724?dopt=Abstract 2) https://scholar.google.com/scholar?cites=16542175527401185218&as_sdt=2005&sciodt=0,5&hl=en 3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014660/ 4) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754073/ 5) https://www.tandfonline.com/doi/full/10.1080/17461391.2018.1499809 6) https://www.ncbi.nlm.nih.gov/pubmed?term=(%22Respiratory+Tract+Infections%2Fepidemiology%22%5BMesh%5D)+AND+%22Exercise%22%5BMajr%5D 7) https://www.ncbi.nlm.nih.gov/pubmed/29486739 8) https://www.ncbi.nlm.nih.gov/pubmed/?term=exercise+AND+(common+cold+OR+upper+respiratory+infections) 9) https://www.ncbi.nlm.nih.gov/pubmed/31035596