Latest & greatest articles for adverse events

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Top results for adverse events

1. ASGE review of adverse events in colonoscopy

ASGE review of adverse events in colonoscopy ASGE STANDARDS OF PRACTICE COMMITTEE REVIEW ASGE review of adverse events in colonoscopy Shivangi T. Kothari, MD, FASGE, 1, * Robert J. Huang, MD, 2, * Aasma Shaukat, MD, MPH, FASGE, 3 Deepak Agrawal, MD, FASGE, 4 James L. Buxbaum, MD, FASGE, 5 Syed M. Abbas Fehmi, MD, MSc, FASGE, 6 Douglas S. Fishman, MD, FASGE, 7 Suryakanth R. Gurudu, MD, FASGE, 8 Mouen A. Khashab, MD, 9 Laith H. Jamil, MD, FASGE, 10 Terry L. Jue, MD, FASGE, 11 Joanna K. Law, MD (...) - cedure. However, adverse events (AEs) related to this routinely performed procedure for screening, diagnostic, ortherapeuticpurposesareanimportantclinicalconsideration.ThepurposeofthisdocumentfromtheAmerican Society for Gastrointestinal Endoscopy’s Standards of Practice Committee is to provide an update on estimates of AEs related to colonoscopy in an evidence-based fashion. A systematic review and meta-analysis of population- based studies was conducted for the 3 most common and important serious

2020 American Society for Gastrointestinal Endoscopy

2. Growth differentiation factor-15 predicts major adverse cardiac events in patients with acute coronary syndrome: a systematic review and meta-analysis

Growth differentiation factor-15 predicts major adverse cardiac events in patients with acute coronary syndrome: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content

2020 PROSPERO

3. Safety and Adverse Events after Targeted Lung Denervation for Symptomatic Moderate to Severe Chronic Obstructive Pulmonary Disease (AIRFLOW). A Multicenter Randomized Controlled Clinical Trial Full Text available with Trip Pro

Safety and Adverse Events after Targeted Lung Denervation for Symptomatic Moderate to Severe Chronic Obstructive Pulmonary Disease (AIRFLOW). A Multicenter Randomized Controlled Clinical Trial Safety and Adverse Events After Targeted Lung Denervation for Symptomatic Moderate to Severe Chronic Obstructive Pulmonary Disease (AIRFLOW). A Multicenter Randomized Controlled Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set (...) to Collections Create a new collection Add to an existing collection Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Am J Respir Crit Care Med Actions , 200 (12), 1477-1486 2019 Dec 15 Safety and Adverse Events After Targeted Lung Denervation for Symptomatic Moderate

2020 EvidenceUpdates

4. ERCP-related adverse events

ERCP-related adverse events ERCP-relatedadverseevents:EuropeanSocietyofGastrointestinal Endoscopy (ESGE) Guideline Authors Jean-MarcDumonceau 1 ,ChristineKapral 2 ,Lars Aabakken 3 ,IoannisS.Papanikolaou 4 ,Andrea Tringali 5,6 ,Geoffroy Vanbiervliet 7 ,Torsten Beyna 8 ,MarioDinis-Ribeiro 9,10 ,IstvanHritz 11 ,AlbertoMariani 12 ,Gregorios Paspatis 13 ,Franco Radaelli 14 , SundeepLakhtakia 15 ,AndrewM.Veitch 16 ,JeaninE.vanHooft 17 Institutions ?1 Gastroenterology Service, Hôpital Civil Marie (...) viewableat: https://doi.org/10.1055/a-1075-4080 Dumonceau Jean-Marc et al. ERCP-related adverse events: ESGEClinical Guideline… Endoscopy1Introduction The range and incidence of adverse events (AEs) related to endoscopic retrograde cholangiopancreatography (ERCP) dif- fer substantially from those related to other endoscopic proce- dures. Familiarity with these AEs is critical for providing patient information during the consent phaseas well as for prophylaxis and management. Adverse events related

2020 European Society of Gastrointestinal Endoscopy

5. The timing of early life adverse events and depressive disorders: a systematic review and meta-analysis

The timing of early life adverse events and depressive disorders: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files

2020 PROSPERO

6. Comparison of immune-related adverse events (irAEs) of combination of PD-(L)1 inhibitors and chemotherapy versus PD-(L)1 inhibitors for non-small cell lung cancer: a meta-analysis of randomised controlled trials

Comparison of immune-related adverse events (irAEs) of combination of PD-(L)1 inhibitors and chemotherapy versus PD-(L)1 inhibitors for non-small cell lung cancer: a meta-analysis of randomised controlled trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD

2020 PROSPERO

7. Efficacy and adverse events of drug-eluting beads transarterial chemoembolization versus conventional transarterial chemoembolization in patients with hepatocellular carcinoma

Efficacy and adverse events of drug-eluting beads transarterial chemoembolization versus conventional transarterial chemoembolization in patients with hepatocellular carcinoma Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2020 PROSPERO

8. Meta-Analysis Comparing the Relative Risk of Adverse Events for Amiodarone Versus Placebo (Abstract)

Meta-Analysis Comparing the Relative Risk of Adverse Events for Amiodarone Versus Placebo Amiodarone has been associated with adverse events that may restrict its use. We performed a meta-analysis of placebo-controlled trials to assess the relative risk of adverse events of amiodarone compared with placebo. In total, 43 randomized trials were included. A total of 11,395 patients were included (5,792 patients randomized to amiodarone and 5,603 patients randomized to placebo). The incident rate (...) of adverse events per 10,000 person-years was higher in the amiodarone group compared with placebo for pulmonary (129 vs 74; relative risk (RR) 1.77, p = 0.002), thyroid (201 vs 42; RR 4.44, p <0.001), hepatic (54 vs 25; RR 2.27, p = 0.01), cardiac (771 vs 450; RR 1.94, p <0.001), neurological (140 vs 76; RR 1.93, p <0.001), and skin (81 vs 23; RR 1.99, p = 0.04) adverse events. Low-dose amiodarone was not associated with statistically significant increase in pulmonary adverse events but was still

2019 EvidenceUpdates

9. During Conscious Sedation the Risk of Adverse Events Is Likely Increased in Obese Children Compared to Those of Healthy Weight

During Conscious Sedation the Risk of Adverse Events Is Likely Increased in Obese Children Compared to Those of Healthy Weight UTCAT3394, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title During Conscious Sedation the Risk of Adverse Events Is Likely Increased in Obese Children Compared to Those of Healthy Weight Clinical Question Are obese children undergoing conscious sedation at increased risk for adverse events (...) compared to children who are at healthy weight? Clinical Bottom Line For children with childhood obesity, conscious sedation may lead to more adverse events including oxyhemoglobin desaturation, nausea and true apnea. However, additional evidence is needed to know if there is any clinical and statistical difference between obese children and healthy weight children during conscious sedation. This is supported by both a cross-sectional retrospective study and a review of literature on the relationship

2019 UTHSCSA Dental School CAT Library

10. Predicting Major Adverse Events in Patients With Acute Myocardial Infarction (Abstract)

Predicting Major Adverse Events in Patients With Acute Myocardial Infarction Early and accurate detection of short-term major adverse cardiac events (MACE) in patients with suspected acute myocardial infarction (AMI) is an unmet clinical need.The goal of this study was to test the hypothesis that adding clinical judgment and electrocardiogram findings to the European Society of Cardiology (ESC) high-sensitivity cardiac troponin (hs-cTn) measurement at presentation and after 1 h (ESC hs-cTn 0/1 (...)  h algorithm) would further improve its performance to predict MACE.Patients presenting to an emergency department with suspected AMI were enrolled in a prospective, multicenter diagnostic study. The primary endpoint was MACE, including all-cause death, cardiac arrest, AMI, cardiogenic shock, sustained ventricular arrhythmia, and high-grade atrioventricular block within 30 days including index events. The secondary endpoint was MACE + unstable angina (UA) receiving early (≤24 h

2019 EvidenceUpdates

11. Performance of cardiac troponins within the HEART score in predicting major adverse cardiac events at the emergency department (Abstract)

Performance of cardiac troponins within the HEART score in predicting major adverse cardiac events at the emergency department This study compared the performance of a single blood draw of high-sensitivity troponin T (hsTnT), high-sensitivity troponin I (hsTnI) and conventional troponin I (cTnI) within a modified HEART score for predicting 30-day MACE at Emergency Department (ED) presentation, and established local reference norms for all three assays by determining the cut-off point which

2019 EvidenceUpdates

12. Inhaled steroids with and without regular formoterol for asthma: serious adverse events. (Abstract)

Inhaled steroids with and without regular formoterol for asthma: serious adverse events. Epidemiological evidence has suggested a link between beta2-agonists and increases in asthma mortality. There has been much debate about whether regular (daily) long-acting beta2-agonists (LABA) are safe when used in combination with inhaled corticosteroids (ICS). This updated Cochrane Review includes results from two large trials that recruited 23,422 adolescents and adults mandated by the US Food and Drug (...) Administration (FDA).To assess the risk of mortality and non-fatal serious adverse events (SAEs) in trials that randomly assign participants with chronic asthma to regular formoterol and inhaled corticosteroids versus the same dose of inhaled corticosteroid alone.We identified randomised trials using the Cochrane Airways Group Specialised Register of trials. We checked websites of clinical trial registers for unpublished trial data as well as FDA submissions in relation to formoterol. The date of the most

2019 Cochrane

13. Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function. (Abstract)

Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function. Before 2016, safety concerns limited metformin use in patients with kidney disease; however, the effectiveness of metformin on clinical outcomes in patients with reduced kidney function remains unknown.To compare major adverse cardiovascular events (MACE) among patients with diabetes and reduced kidney function who continued treatment (...) of 6.6% [IQR, 6.1%-7.2%] at cohort entry). During follow-up (median, 1.0 year for metformin vs 1.2 years for sulfonylurea), there were 1048 MACE outcomes (23.0 per 1000 person-years) among metformin users and 1394 events (29.2 per 1000 person-years) among sulfonylurea users. The cause-specific adjusted hazard ratio of MACE for metformin was 0.80 (95% CI, 0.75-0.86) compared with sulfonylureas, yielding an adjusted rate difference of 5.8 (95% CI, 4.1-7.3) fewer events per 1000 person-years

2019 JAMA

14. Planning to reduce 30-day adverse events after discharge of frail elderly patients with acute heart failure: design and rationale for the DEED FRAIL-AHF trial. (Abstract)

Planning to reduce 30-day adverse events after discharge of frail elderly patients with acute heart failure: design and rationale for the DEED FRAIL-AHF trial. To demonstrate the efficacy of a system for comprehensive care transfer (Multilevel Guided Discharge Plan [MGDP]) for frail older patients diagnosed with acute heart failure (AHF) and to validate the results of MGDP implementation under real clinical conditions. The MGDP seeks to reduce the number of adverse outcomes within 30 days

2019 Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias Controlled trial quality: uncertain

15. Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study. (Abstract)

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study. Randomized trials demonstrate no benefit from antibiotic treatment exceeding the shortest effective duration.To examine predictors and outcomes associated with excess duration of antibiotic treatment.Retrospective cohort study.43 hospitals in the Michigan Hospital Medicine Safety Consortium.6481 general care medical patients with pneumonia.The primary outcome (...) , or did not have a total antibiotic treatment duration documented at discharge were more likely to receive excess treatment. Excess treatment was not associated with lower rates of any adverse outcomes, including death, readmission, emergency department visit, or Clostridioides difficile infection. Each excess day of treatment was associated with a 5% increase in the odds of antibiotic-associated adverse events reported by patients after discharge.Retrospective design; not all patients could

2019 Annals of Internal Medicine

16. Association of Preoperative Renin-Angiotensin System Inhibitors With Prevention of Postoperative Atrial Fibrillation and Adverse Events: A Systematic Review and Meta-analysis Full Text available with Trip Pro

Association of Preoperative Renin-Angiotensin System Inhibitors With Prevention of Postoperative Atrial Fibrillation and Adverse Events: A Systematic Review and Meta-analysis Postoperative atrial fibrillation (POAF) is a well-known complication after cardiac surgery. Renin-angiotensin system inhibitors (RASIs) have been suggested as an upstream therapy for selected patients with AF; however, evidence in the surgical setting is limited.To evaluate the role of preoperative RASIs in prevention (...) of POAF and adverse events for patients undergoing cardiac surgery.The PubMed database and the Cochrane Library from inception until December 31, 2018, were searched by using the keywords renin-angiotensin system inhibitors OR angiotensin-converting enzyme inhibitors OR angiotensin receptor blocker OR aldosterone antagonist AND cardiac surgery. ClinicalTrials.gov was searched from inception until December 31, 2018, by using the keywords postoperative atrial fibrillation.Randomized clinical trials

2019 EvidenceUpdates

17. What Is the Diagnostic Accuracy of Cardiac Biomarkers for the Prediction of Adverse Cardiac Events in Patients Presenting With Acute Syncope? Full Text available with Trip Pro

What Is the Diagnostic Accuracy of Cardiac Biomarkers for the Prediction of Adverse Cardiac Events in Patients Presenting With Acute Syncope? What Is the Diagnostic Accuracy of Cardiac Biomarkers for the Prediction of Adverse Cardiac Events in Patients Presenting With Acute Syncope? - Annals of Emergency Medicine Email/Username: Password: Remember me Search Terms Search within Search Share this page Access provided by Volume 73, Issue 5, Pages 511–513 What Is the Diagnostic Accuracy of Cardiac (...) Biomarkers for the Prediction of Adverse Cardiac Events in Patients Presenting With Acute Syncope? x Jason R. West , MD (EBEM Commentator) , x James Russell , MD (EBEM Commentator) Department of Emergency Medicine, Lincoln Medical and Mental Health Center, Bronx, NY DOI: | Publication History Published online: August 27, 2018 Expand all Collapse all Article Outline Take-Home Message The sensitivity of brain-type natriuretic peptides and troponin for identifying syncopal patients at risk for major cardiac

2019 Annals of Emergency Medicine Systematic Review Snapshots

18. Effect of Albuterol Premedication vs Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies: The REACT Randomized Clinical Trial (Abstract)

Effect of Albuterol Premedication vs Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies: The REACT Randomized Clinical Trial Tonsillectomy is a common pediatric procedure for the treatment of sleep-disordered breathing and chronic tonsillitis. Up to half of children having this procedure experience a perioperative respiratory adverse event.To determine whether inhaled albuterol sulfate (salbutamol sulfate) premedication decreases the risk (...) of perioperative respiratory adverse events in children undergoing anesthesia for tonsillectomy.A randomized, triple-blind, placebo-controlled trial (the Reducing Anesthetic Complications in Children Undergoing Tonsillectomies [REACT] trial) was conducted at Perth Children's Hospital (formerly Princess Margaret Hospital for Children), the only tertiary pediatric hospital in Western Australia. Participants included 484 children aged 0 to 8 years who were undergoing anesthesia for tonsillectomy. The study

2019 EvidenceUpdates

19. Adverse Events Associated with Nonsurgical Treatments for Urinary Incontinence in Women: a Systematic Review (Abstract)

Adverse Events Associated with Nonsurgical Treatments for Urinary Incontinence in Women: a Systematic Review Urinary incontinence (UI) is a common malady in women. Numerous nonsurgical treatments are available, each associated with risk of adverse events (AEs).We systematically reviewed nonsurgical interventions for urgency, stress, or mixed UI in women, focusing on AEs. We searched MEDLINE®, Cochrane Central Trials Registry, Cochrane Database of Systematic Reviews, and Embase® through December

2019 EvidenceUpdates

20. Serious adverse events and lifetime risk of reoperation after elective shoulder replacement: population based cohort study using hospital episode statistics for England. Full Text available with Trip Pro

Serious adverse events and lifetime risk of reoperation after elective shoulder replacement: population based cohort study using hospital episode statistics for England. To provide accurate risk estimates of serious adverse events after elective shoulder replacement surgery for arthritis, including age and sex specific estimates of the lifetime risk of revision surgery.Population based cohort study.Hospital episode statistics for NHS England, including civil registration mortality data.58 054 (...) elective shoulder replacements in 51 895 adults (aged ≥50 years) between April 1998 and April 2017.The lifetime risk of revision surgery, calculated using an actuarial life table approach and the cumulative probability method. Rates of serious adverse events at 30 and 90 days post-surgery: pulmonary embolism, myocardial infarction, lower respiratory tract infection, acute kidney injury, urinary tract infection, cerebrovascular events, and all cause death. Secondary outcome measures were the number

2019 BMJ