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1. Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non-cardiac surgery Full Text available with Trip Pro

Anaesthesia Scientific Research Fund and Wu Jieping Medical Foundation, Beijing, China. Study drugs were manufactured and supplied by Jiangsu Hengrui Medicine Co, L … Y Sun et al. Drug Des Devel Ther 13, 2911-2922. 2019. PMID 31695323. Postoperative continuous infusion of dexmedetomidine did not decrease the incidence of postoperative delirium in elderly patients admitted to general surgical wards after … D Miller et al. Cochrane Database Syst Rev 8 (8), CD012317. 2018. PMID 30129968. - Review We

2020 EvidenceUpdates

2. Joint AAD-NPF guidelines of care for the management and treatment of psoriasis in pediatric patients Full Text available with Trip Pro

, Minnesota , MD c , x Daniela Kroshinsky Affiliations Massachusetts General Hospital, Boston, Massachusetts , MD, MPH d , x Amy S. Paller Affiliations Northwestern University Feinberg School of Medicine, Chicago, Illinois , MD e , x April W. Armstrong Affiliations University of Southern California, Los Angeles, California , MD, MPH f , x Cody Connor Affiliations University of Alabama, Birmingham, Alabama , MD g , x Boni E. Elewski Affiliations University of Alabama, Birmingham, Alabama , MD g , x Joel M

2020 American Academy of Dermatology

3. AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis

AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis Journal Pre-proof AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis Joseph D. Feuerstein, MD, Kim L. Isaacs, MD, Yecheskel Schneider, MD, Shazia Mehmood Siddique, MD, MS, Yngve Falck-Ytter, MD, Siddharth Singh, MD, MS, on behalf of the American Gastroenterological Association Institute Clinical Guidelines Committee PII: S0016-5085(20)30018-4 DOI: https://doi.org (...) to the journal pertain. © 2020 by the AGA Institute1 AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis Joseph D. Feuerstein MD 1 , Kim L. Isaacs MD 2 , Yecheskel Schneider MD 3 , Shazia Mehmood Siddique MD, MS 3 , Yngve Falck-Ytter MD 4 , and Siddharth Singh MD, MS 5 on behalf of the American Gastroenterological Association Institute Clinical Guidelines Committee 1 Division of Gastroenterology and Center for Inflammatory Bowel Diseases, Beth Israel Deaconess Medical

2020 American Gastroenterological Association Institute

5. Disorders of the Hepatic and Mesenteric Circulation Full Text available with Trip Pro

. Changes in the anticoagulant system in cirrhosis can cause relative hypercoagulability that are not detected by conventional tests of hemostasis. Assessment of bleeding risk in cirrhosis There is poor correlation between international normalized ratio (INR) and thrombin production in cirrhosis ( ). In addition, INR was developed specifically as a marker of anticoagulant activity of vitamin K antagonists (VKAs). The mathematical derivation of INR from the PT depends on the international sensitivity (...) at platelet levels of 50–60,000/uL ( ). TPO-receptor agonists (eltrombopag, lusutrombopag, and avatrombopag) have demonstrated to effectively stimulate thrombopoiesis in patients with cirrhosis and thrombocytopenia ( ). In two large phase 3 randomized trials, the use of avatrombopag at 40–60 mg/d for 5 days significantly reduced the need for platelet transfusions or rescue procedures for bleeding in patients with thrombocytopenia and chronic liver disease undergoing a scheduled procedure ( ). Similar

2020 American College of Gastroenterology

6. KDOQI Clinical Practice Guidelines for Nutrition in CKD

- Oral, Enteral, and Parental Nutrition ……………………… ……………………………….. 103 4.2 Nutrition Supplementation - Dialysate………………………………………..…….…… 115 4.3 Long Chain Omega-3 Polyunsaturated Fatty Acids ………………………… 119 Guideline 5: Micronutrients.……………………………………………………….…………. 128 5.0 General Guidance ……………………………………………………………………….. 128 5.1 Folic acid (with and without other B Vitamins) ……..…………………………………… 132 5.2 Vitamin C ………………………………………………………………………………… 137 5.3 Vitamin D ………………………………………………………………………………… 142 5.4 Vitamin E (...) in adults with CKD 1-5D, non-dialysis and transplant? Micronutrients: intervention questions What is the effect of micronutrient intake (B vitamins, vitamins C, D, E and K and selenium and zinc) on outcomes in adults with CKD 1-5D, non-dialysis and transplant? Electrolytes: intervention questions What is the effect of dietary intake of (acid-base, calcium, phosphorus, potassium, magnesium, sodium) on (electrolyte) biomarkers and other health outcomes in adults with CKD 1-5D, non-dialysis and transplant

2020 National Kidney Foundation

7. Promoting Physical Activity in Schools: A Rapid Review

LITERATURE REVIEW QUESTION 7 4 LITERATURE SEARCH 7 5 RELEVANCE ASSESSMENT 8 6 RESULTS OF THE SEARCH 9 7 CRITICAL APPRAISAL 10 8 DESCRIPTION OF INCLUDED PAPERS 10 9 RESULTS 14 10 SYNTHESIS 18 11 APPLICABILITY AND TRANSFERABILITY 22 12 RECOMMENDATIONS 26 13 ACKNOWLEDGEMENTS 27 REFERENCES 28 DATA REFERENCES 30 APPENDIX A: STUDENT PHYSICAL ACTIVITY RATES, 2017 31 APPENDIX B: PLEDGE PROGRAM – PHYSICAL ACTIVITY PROGRAMS 32 APPENDIX C: PLEDGE PROGRAM – DAILY PHYSICAL ACTIVITY 33 APPENDIX D: SEARCH STRATEGY 34 (...) multicomponent interventions (e.g., education activities, policy action, environmental changes, etc.) to increase student physical activity. c. Engage students, especially those less likely to participate, in the planning and delivery of multicomponent interventions to increase physical activity. d. Ensure that schools have the resources, capacity and support to provide physical activity opportunities to students. 2. Partner with community organizations and political leaders to advocate for and promote

2020 Peel Health Library

8. A summary of childcare in the east end of Glasgow

. Population level estimates at data zone level. Edinburgh: NRS; 2018. 3. Children in Scotland. Report on the provision and use of childcare in the CHANGE project area. Glasgow: CIS; 2018. 37 Appendices Appendix 1. Summary of pre-school nurseries in the CHANGE area. Table A1.1. Summary of preschool nurseries in the CHANGE area. Source: Children in Scotland 3 . Nursery name Type of service Capacity d No. of waiting places e Service provision Recent Care Inspectorate grading f HYDE N SEEK - Bridgeton Private

2020 Glasgow Centre for Population Health

9. Improving Human Papilloma Virus (HPV) Vaccine Uptake

LITERATURE REVIEW QUESTION 7 4 LITERATURE SEARCH 7 5 RELEVANCE ASSESSMENT 8 6 RESULTS OF SEARCH 8 7 CRITICAL APPRAISAL 9 8 DESCRIPTION OF INCLUDED PAPERS 9 9 SYNTHESIS OF FINDINGS 12 10 LIMITATIONS 19 11 APPLICABILITY AND TRANSFERABILITY 20 12 RECOMMENDATIONS 23 13 ACKNOWLEDGEMENTS 25 TEXT REFERENCES 26 DATA REFERENCES 28 APPENDICES 29 APPENDIX A: SEARCH STRATEGY 30 APPENDIX B: LITERATURE SEARCH FLOWCHART 34 APPENDIX C: CRITICAL APPRAISAL SUMMARY TABLE 35 APPENDIX D: DATA EXTRACTION TABLES 36 APPENDIX E (...) type. Meta-analyses were also performed for the prevalence of HPV infection (two studies) and the prevalence of genital warts (three studies). Using Grading of Recommendations Assessment, Development and Evaluation (GRADE), the evidence was rated as moderate quality for vaccine coverage and low for prevalence of HPV infection and genital warts (Appendix D). Kang et al. (2018): Completeness of Human Papilloma Virus Vaccination: A Systematic Review. 13 The objective of this moderate-quality

2020 Peel Health Library

10. Herbal cannabis and pharmaceutical cannabinoid treatment following motor vehicle accidents: A state of the science review

not appropriate for patients who; (The College of Family Physicians of Canada, 2014) a. are under the age of 25 b. have a personal history or strong family history of psychosis c. have a current or past cannabis use disorder d. have an active substance use disorder e. have cardiovascular (angina, peripheral vascular disease, cerebrovascular disease, arrhythmia) or respiratory disease f. are pregnant, planning to become pregnant or are breastfeeding The College recognizes that there are sometimes circumstances

2020 Therapeutics Letter

11. Teaching Information Literacy Skills to Public Health Staff: A Rapid Review

1 EXECUTIVE SUMMARY 2 1 ISSUE 4 2 CONTEXT 4 3 LITERATURE REVIEW QUESTION 6 4 LITERATURE SEARCH 7 5 RELEVANCE ASSESSMENT 7 6 RESULTS OF THE SEARCH 8 7 CRITICAL APPRAISAL 9 8 DESCRIPTION OF INCLUDED PAPERS 9 9 FINDINGS 11 10 APPLICABILITY AND TRANSFERABILITY 13 11 RECOMMENDATIONS 15 12 ACKNOWLEDGEMENTS 16 REFERENCES 17 APPENDICES 18 APPENDIX A: SEARCH STRATEGY 19 APPENDIX B: LITERATURE SEARCH FLOWCHART 21 APPENDIX C: DATA EXTRACTION TABLE 22 APPENDIX D: APPLICABILITY AND TRANSFERABILITY WORKSHEET (...) (Appendix D). Political Acceptability The recommendations would likely be politically acceptable. • The culture at Peel supports professional development and EIDM, which is expected to continue as part of workforce development. • Despite current public health sector changes, the need to build information seeking skills will continue. Training developed by Peel would likely be considered useful within the new regional public health entities. Social Acceptability The recommendations would likely

2020 Peel Health Library

12. Recognition and Initial Management of Fulminant Myocarditis: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

Management of Fulminant Myocarditis A Scientific Statement From the American Heart Association , MD, MS, Chair , MD, FAHA, Vice Chair , MD, FAHA , MD , MD, MS, FAHA , MD, MPH , MD, FAHA , MD, FAHA , MD, FAHA , PharmD, MS, FAHA Robb D. Kociol , Leslie T. Cooper , James C. Fang , Javid J. Moslehi , Peter S. Pang , Marwa A. Sabe , Ravi V. Shah , Daniel B. Sims , Gaetano Thiene , Orly Vardeny , Originally published 6 Jan 2020 Circulation. 2020;141:e69–e92 Abstract Fulminant myocarditis (FM) is an uncommon (...) ability to augment stroke volume in the acutely affected nondilated heart. Consider hypersensitivity myocarditis, a subset of eosinophilic myocarditis, generally presenting as FM with peripheral eosinophilia (65% of patients), rash, or elevated LFTs. Patients often will have a fever and high risk (43%) of death, transplantation, or VAD placement at 120 d. An EMB is often necessary for definitive diagnosis. Common causative agents are antibiotics such as β-lactams and minocycline and certain central

2020 American Heart Association

13. Prevention of Early-Onset Group B Streptococcal Disease in Newborns

in enrichment broth, a subculture is made onto blood agar plates, followed by identifica- tion of any bacterial colonies as GBS using latex agglutination with group B antisera, chromogenic agars, DNA probes,or nucleic acid amplification tests. c Inducible resistance to clindamycin is detected by the D-zone test, which tests the isolate for resistance to clindamycin.* *Determination of susceptibility to clindamycin typically also includes analysis by the D-zone test which indicates the pres- ence (...) of inducible resistance from macrolides including eryth- romycin. This macrolide-induced resistance is produced through an induced enzyme that alters the common ribosomal binding site for macrolides and clindamycin, resulting in clin- damycin failure (Woods CR. Macrolide-inducible resistance to clindamycin and the D-test. Pediatr Infect Dis J 2009;28:1115–8.) Therefore, in vitro susceptibility or resistance to erythromycin may be reported as a laboratory adjunct to clindamycin testing. If reported, it does

2020 American College of Obstetricians and Gynecologists

14. Treatment for Insomnia and Disrupted Sleep Behavior in Children and Adolescents with Autism Spectrum Disorder

to subcommittee meetings where drafts of manuscripts were 20 reviewed. 21 22 DISCLOSURE 23 4 1 A. Buckley has nothing to disclose. 2 3 D. Hirtz is on the executive Boards of the Pediatric Epilepsy Research Foundation, the Cerebral 4 Palsy Research Network, The CHILD-BRITE network, ( Canada), The North American 5 Antiepileptic Drug Pregnancy Registry and the TENDR group (Targeting Environmental 6 Neurodevelopmental Risks), and has received funding for travel to meetings from those 7 organizations. She is also (...) Behavioral Pediatrics Grant. 10 11 D. Coury serves on an advisory board for Cognoa; receives research grant support from Neurim 12 Pharmaceuticals and Stalicla SA; serves on a data safety monitoring committee for AMO 13 Pharma; serves as co-investigator for the National Center for Complementary and Integrative 14 Health (NCCIH) study Fatty Acid Supplementation in Children with ASD (Omega Heroes; 15 ClinicalTrials.gov identifier NCT03550209), examining an omega-3 supplement to treat autism 16 spectrum

2020 American Academy of Neurology

15. Randomized Controlled Trial of Mobile Closed-Loop Control

. - Randomized Controlled Trial Our findings show that glycaemic control measured by time in the glucose range of 70-180 mg/dL (3·9-10·0 mmol/L) is improved by initiation of CSII in adults with type 1 dD Rodbard. Diabetes Technol Ther 19 (S3), S25-S37. Jun 2017. PMID 28585879. - Review Continuous Glucose Monitoring (CGM) has been demonstrated to be clinically valuable, reducing risks of hypoglycemia and hyperglycemia, glycemic variability (GV), and impr … M Langendam et al. Cochrane Database Syst Rev 1 (1

2020 EvidenceUpdates

16. 2020-2023 Value Assessment Framework

and Economic Review, 2020 Page iv 2020-2023 Value Assessment Framework 5. Potential Budget Impact Analysis 39 5.1. Overview 39 5.2. Methods 40 5.3 Access and Affordability Alert 42 6. Procedures for Report Generation, Stakeholder Engagement, and Public Processes 43 6.1 Topic Selection 43 6.2 Timelines 44 6.3 Stakeholder Engagement 46 6.4 Public Meetings 53 References 60 Appendices 63 A. Glossary 63 B. List of Major Revisions to 2017-2019 Framework 67 C. Review Timelines 68 D. Cost-Effectiveness Threshold

2020 California Technology Assessment Forum

17. Antibiotic Use for the Urgent Management of Dental Pain and Intra-oral Swelling Clinical Practice Guideline Full Text available with Trip Pro

abscess. Only clinicians who are authorized or trained to perform the specified treatment should do so. † Adult patients with pulp necrosis and symptomatic apical periodontitis should be instructed to call if their condition deteriorates (progression of disease to a more severe state) or if the referral to receive DCDT within 1-2 d is not possible. ‡ For adult patients with pulp necrosis and symptomatic apical periodontitis, a delayed prescription should be provided if DCDT is not immediately (...) -Dutra, K.E., and Roberts, R.M. Hicks LA. The Core elements of outpatient antibiotic stewardship. ( Available at: ) . § Clinicians should reevaluate within 3 d (for example, in-person visit or phone call). Dentists should instruct patients to discontinue antibiotics 24 h after their symptoms resolve, irrespective of reevaluation after 3 d. ¶ Although the expert panel recommends both amoxicillin and penicillin as first-line treatments, amoxicillin is preferred over penicillin because it is more

2020 American Dental Association Guidelines

18. Position Statement on the medicinal use of Cannabinoids in Pain Medicine

, Radbruch L, Petzke F, Häuser W. Cannabis-based medicines for chronic neuropathic pain in adults. Cochrane Database of Systematic Reviews 2018, Issue 3. Art. No.: CD012182. DOI: 10.1002 /14651858.CD012182.pub2 3. Stockings E, Campbell G, Hall WD, Nielsen S, Zagic D, Rahman R, et al. Cannabis and cannabinoids for the treatment of people with chronic non-cancer pain conditions: a systematic review and meta-analysis of controlled and observational studies. PAIN. 2018;159(10):1932-54. 4. National Academies

2020 Faculty of Pain Medicine

19. European surveillance of Clostridioides (Clostridium) difficile infections - surveillance protocol version 2.4

further information about options to participate should contact their National Focal Point for Healthcare- Associated Infections in their country 3 . 1 Consortium composed of Leiden University Medical Center, the Netherlands (E.J. Kuijper, coordination), University of Leeds and the Health Protection Agency, England, United Kingdom (M. Wilcox), University Hospital of Wales, Cardiff, United Kingdom (V. Hall), Centre for Infectious Disease Control, RIVM, Bilthoven, the Netherlands (D. Notermans), Charité

2020 European Centre for Disease Prevention and Control - Technical Guidance

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