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1. Ebola virus infection

Ebola virus infection Ebola virus infection - Symptoms, diagnosis and treatment | BMJ Best Practice   Search  Ebola virus infection Last reviewed: February 2019 Last updated: February 2019 Important updates 20 Feb 2019 Ebola outbreak in DRC: update The World Health Organization (WHO) announced an Ebola outbreak in the Democratic Republic of the Congo (DRC) in August 2018. As of 12 February 2019, 823 cases (762 confirmed, 61 probable), including 517 deaths, have been reported in the North (...) Kivu and Ituri provinces. A total of 68 health workers have been infected. This makes it the second largest outbreak of Ebola since the 2014-2016 outbreak in West Africa. A disproportionate number of women and children have been infected during this outbreak. WHO rate the risk of national and regional spread as very high, but the global risk level is low. The affected areas share borders with Rwanda and Uganda, and WHO notes that the prolonged humanitarian crisis and deterioration of security

2019 BMJ Best Practice

2. 2014 Ebola virus disease outbreak and issues raised: follow-up to the Special Session of the Executive Board on the Ebola Emergency (resolution EBSS3.R1) and the Sixty-eighth World Health Assembly (decision WHA68(10)): high-level design for a new WHO heal

2014 Ebola virus disease outbreak and issues raised: follow-up to the Special Session of the Executive Board on the Ebola Emergency (resolution EBSS3.R1) and the Sixty-eighth World Health Assembly (decision WHA68(10)): high-level design for a new WHO heal 2014 Ebola virus disease outbreak and issues raised: follow-up to the Special Session of the Executive Board on the Ebola Emergency (‎resolution EBSS3.R1)‎ and the Sixty-eighth World Health Assembly (‎decision WHA68(‎10)‎)‎: high-level design (...) for a new WHO health emergencies programme: report by the Director-General JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links 2014 Ebola virus disease outbreak and issues raised: follow-up to the Special Session of the Executive Board on the Ebola Emergency (‎resolution EBSS3.R1)‎ and the Sixty-eighth World Health Assembly (‎decision WHA68(‎10)‎)‎: high-level design for a new WHO health

2016 WHO

3. Ebola and Marburg haemorrhagic fevers: outbreaks and case locations

Ebola and Marburg haemorrhagic fevers: outbreaks and case locations Ebola and Marburg haemorrhagic fevers: outbreaks and case locations - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Ebola and Marburg haemorrhagic fevers: outbreaks and case locations Information about incidents and outbreaks of Ebola and Marburg, both viral haemorrhagic fevers (VHF). Published 23 March 2014 Last updated 6 August 2019 (...) — From: Contents Current incidents and outbreaks Thursday 1 August 2019 marked one year since confirmation of the outbreak of Ebola virus disease in eastern Democratic Republic of the Congo ( . Suspected cases continue to be detected and followed up on a daily basis. The World Health Organisation ( . On 17 July 2019, the . There is conflict and a prolonged humanitarian crisis in the affected areas, with large numbers of displaced people. There is cross-border movement of people and trade to both

2019 Public Health England

4. Comparative performance of four rapid Ebola antigen-detection lateral flow immunoassays during the 2014-2016 Ebola epidemic in West Africa. (PubMed)

Comparative performance of four rapid Ebola antigen-detection lateral flow immunoassays during the 2014-2016 Ebola epidemic in West Africa. Without an effective vaccine, as was the case early in the 2014-2016 Ebola Outbreak in West Africa, disease control depends entirely on interrupting transmission through early disease detection and prompt patient isolation. Lateral Flow Immunoassays (LFI) are a potential supplement to centralized reference laboratory testing for the early diagnosis of Ebola (...) Virus Disease (EVD). The goal of this study was to assess the performance of commercially available simple and rapid antigen detection LFIs, submitted for review to the WHO via the Emergency Use Assessment and Listing procedure. The study was performed in an Ebola Treatment Centre laboratory involved in EVD testing in Sierra Leone. In light of the current Ebola outbreak in May 2018 in the Democratic Republic of Congo, which highlights the lack of clarity in the global health community about

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2019 PLoS ONE

6. Ebola virus infection

Ebola virus infection Ebola virus infection - Symptoms, diagnosis and treatment | BMJ Best Practice   Search  Ebola virus infection Last reviewed: February 2019 Last updated: February 2019 Important updates 20 Feb 2019 Ebola outbreak in DRC: update The World Health Organization (WHO) announced an Ebola outbreak in the Democratic Republic of the Congo (DRC) in August 2018. As of 12 February 2019, 823 cases (762 confirmed, 61 probable), including 517 deaths, have been reported in the North (...) Kivu and Ituri provinces. A total of 68 health workers have been infected. This makes it the second largest outbreak of Ebola since the 2014-2016 outbreak in West Africa. A disproportionate number of women and children have been infected during this outbreak. WHO rate the risk of national and regional spread as very high, but the global risk level is low. The affected areas share borders with Rwanda and Uganda, and WHO notes that the prolonged humanitarian crisis and deterioration of security

2018 BMJ Best Practice

7. Clinical Surveillance and Evaluation of Suspected Ebola Cases in a Vaccine Trial During an Ebola Epidemic: The Sierra Leone Trial to Introduce a Vaccine Against Ebola. (PubMed)

Clinical Surveillance and Evaluation of Suspected Ebola Cases in a Vaccine Trial During an Ebola Epidemic: The Sierra Leone Trial to Introduce a Vaccine Against Ebola. ClinicalTrials.gov [NCT02378753] and Pan African Clinical Trials Registry [PACTR201502001037220].

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2018 Journal of Infectious Diseases

8. Epidemiological characteristics, clinical manifestations, and treatment outcome of 139 paediatric Ebola patients treated at a Sierra Leone Ebola treatment center. (PubMed)

Epidemiological characteristics, clinical manifestations, and treatment outcome of 139 paediatric Ebola patients treated at a Sierra Leone Ebola treatment center. The West Africa Ebola Virus Disease (EVD) outbreak in 2014-2016 was declared by the World Health Organization (WHO) a public health emergency of international concern. Most of the previous studies done in Sierra Leone relating to the clinical and epidemiological features of EVD during the 2014-2016 West African outbreak focused (...) on adult EVD patients. There have been conflicting reports about the effects of EVD on children during previous outbreaks.This is an observational retrospective analysis of medical data of all laboratory confirmed paediatric EVD patients below 15 years of age who were admitted at the 34 Military Hospital Ebola Treatment Center (ETC) in Wilberforce, Sierra Leone between June 2014 to April 2015. We analyzed the sociodemographic and clinical characteristics of paediatric EVD cases contained in case report

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2019 BMC Infectious Diseases

9. Early transmission and case fatality of Ebola virus at the index site of the 2013-16 west African Ebola outbreak: a cross-sectional seroprevalence survey. (PubMed)

Early transmission and case fatality of Ebola virus at the index site of the 2013-16 west African Ebola outbreak: a cross-sectional seroprevalence survey. To date, epidemiological studies at the index site of the 2013-16 west African Ebola outbreak in Meliandou, Guinea, have been restricted in their scope. We aimed to determine the occurrence of previously undocumented Ebola virus disease (EVD) cases and infections, and to reconstruct transmission events.This cross-sectional seroprevalence (...) survey of the adult population of Meliandou used a highly specific oral fluid test and detailed interviews of all households in the village and key informants. Each household was interviewed, with all members prompted to describe the events of the outbreak, any illness within the household, and possible contact with suspected cases. Information for deceased individuals was provided by relatives living in the same household. Symptoms were based on Ebola virus Makona variant EVD case definitions

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2019 Lancet infectious diseases

10. Surviving Ebola: A historical cohort study of Ebola mortality and survival in Sierra Leone 2014-2015. (PubMed)

Surviving Ebola: A historical cohort study of Ebola mortality and survival in Sierra Leone 2014-2015. While a number of predictors for Ebola mortality have been identified, less is known about post-viral symptoms. The identification of acute-illness predictors for post-viral symptoms could allow the selection of patients for more active follow up in the future, and those in whom early interventions may be beneficial in the long term. Studying predictors of both mortality and post-viral symptoms (...) within a single cohort of patients could also further our understanding of the pathophysiology of survivor sequelae.We performed a historical cohort study using data collected as part of routine clinical care from an Ebola Treatment Centre (ETC) in Kerry Town, Sierra Leone, in order to identify predictors of mortality and of post-viral symptoms. Variables included as potential predictors were sex, age, date of admission, first recorded viral load at the ETC and symptoms (recorded upon presentation

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2018 PLoS ONE

11. Anti-Ebola therapy for patients with Ebola virus disease: a systematic review. (PubMed)

Anti-Ebola therapy for patients with Ebola virus disease: a systematic review. Management of Ebola virus disease (EVD) has historically focused on infection prevention, case detection and supportive care. Several specific anti-Ebola therapies have been investigated, including during the 2014-2016 West African outbreak. Our objective was to conduct a systematic review of the effect of anti-Ebola virus therapies on clinical outcomes to guide their potential use and future evaluation.We searched (...) PubMed, EMBASE, Global Health, Cochrane Library, African Index Medicus, WHOLIS (inception-9 April 2018), and trial registries for observational studies or clinical trials, in any language, that enrolled patients with confirmed EVD who received therapy targeting Ebola virus and reported on mortality, symptom duration, or adverse effects.From 11,257 citations and registered trials, we reviewed 55 full-text citations, of which 35 met eligibility criteria (1 randomized clinical trial (RCT), 8 non

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2019 BMC Infectious Diseases

12. Ebola exposure, illness experience, and Ebola antibody prevalence in international responders to the West African Ebola epidemic 2014-2016: A cross-sectional study. (PubMed)

Ebola exposure, illness experience, and Ebola antibody prevalence in international responders to the West African Ebola epidemic 2014-2016: A cross-sectional study. Healthcare and other front-line workers are at particular risk of infection with Ebola virus (EBOV). Despite the large-scale deployment of international responders, few cases of Ebola virus disease have been diagnosed in this group. Since asymptomatic or pauci-symptomatic infection has been described, it is plausible that infections (...) have occurred in healthcare workers but have escaped being diagnosed. We aimed to assess the prevalence of asymptomatic or pauci-symptomatic infection, and of exposure events, among returned responders to the West African Ebola epidemic 2014-2016.We used snowball sampling to identify responders who had returned to the UK or Ireland, and used an online consent and questionnaire to determine their exposure to EBOV and their experience of illness. Oral fluid collection devices were sent and returned

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2017 PLoS medicine

13. Asymptomatic infection and unrecognised Ebola virus disease in Ebola-affected households in Sierra Leone: a cross-sectional study using a new non-invasive assay for antibodies to Ebola virus. (PubMed)

Asymptomatic infection and unrecognised Ebola virus disease in Ebola-affected households in Sierra Leone: a cross-sectional study using a new non-invasive assay for antibodies to Ebola virus.

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2017 Lancet infectious diseases

14. Patterns of demand for non-Ebola health services during and after the Ebola outbreak: panel survey evidence from Monrovia, Liberia (PubMed)

Patterns of demand for non-Ebola health services during and after the Ebola outbreak: panel survey evidence from Monrovia, Liberia The recent Ebola virus disease (EVD) outbreak was unprecedented in magnitude, duration and geographic scope. Hitherto there have been no population-based estimates of its impact on non-EVD health outcomes and health-seeking behaviour.We use data from a population-based panel survey conducted in the late-crisis period and two postcrisis periods to track trends in (1 (...) outbreak, as measured by witnessing dead bodies or knowing Ebola victims, negatively predicts trust and usage and (4) exposure to government-organised community outreach predicts higher trust and usage. These patterns do not obtain in the post-crisis period.Supply-side and socioeconomic factors are insufficient to account for lower health-seeking behaviour during the crisis. Rather, it appears that distrust and negative EVD-related experiences reduced demand during the outbreak. The absence

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2016 BMJ global health

15. 2014 Ebola virus disease outbreak and follow-up to the special session of the Executive Board on Ebola: options for a contingency fund to support WHO’s emergency response capacity: report of the Programme, Budget and Administration Committee of the Execut

2014 Ebola virus disease outbreak and follow-up to the special session of the Executive Board on Ebola: options for a contingency fund to support WHO’s emergency response capacity: report of the Programme, Budget and Administration Committee of the Execut 2014 Ebola virus disease outbreak and follow-up to the special session of the Executive Board on Ebola: options for a contingency fund to support WHO’s emergency response capacity: report of the Programme, Budget and Administration Committee (...) of the Executive Board to the Sixty-eighth World Health Assembly JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links 2014 Ebola virus disease outbreak and follow-up to the special session of the Executive Board on Ebola: options for a contingency fund to support WHO’s emergency response capacity: report of the Programme, Budget and Administration Committee of the Executive Board to the Sixty

2015 WHO

16. IHR and Ebola: Special Session of the Executive Board on the Ebola Emergency

IHR and Ebola: Special Session of the Executive Board on the Ebola Emergency IHR and Ebola: Special Session of the Executive Board on the Ebola Emergency JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links IHR and Ebola: Special Session of the Executive Board on the Ebola Emergency View/ Open View Statistics Altmetrics Share Citation Executive Board, Special Session on Ebola (...) . (‎2015)‎. IHR and Ebola: Special Session of the Executive Board on the Ebola Emergency. World Health Organization. Gov't Doc # EBSS/3/INF./4 Collections Language English Metadata Related items Showing items related by title and MeSH subject.  执行委员会 关于埃博拉问题特别会议 (‎ EBSS/3/INF./5 , 2015 )‎  Consejo Ejecutivo, Reunión extraordinaria sobre el ebola (‎ EBSS/3/INF./5 , 2015 )‎  执行委员会 关于埃博拉问题特别会议 (‎ EBSS/3/INF./1 , 2015 )‎ View Item

2015 WHO

17. Ebola at end-2014: ‘Getting to Zero’: Special Session of the Executive Board on the Ebola Emergency

Ebola at end-2014: ‘Getting to Zero’: Special Session of the Executive Board on the Ebola Emergency Ebola at end-2014: ‘Getting to Zero’: Special Session of the Executive Board on the Ebola Emergency JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Ebola at end-2014: ‘Getting to Zero’: Special Session of the Executive Board on the Ebola Emergency View/ Open View Statistics (...) Altmetrics Share Citation Executive Board, Special Session on Ebola . (‎2015)‎. Ebola at end-2014: ‘Getting to Zero’: Special Session of the Executive Board on the Ebola Emergency. World Health Organization. Gov't Doc # EBSS/3/INF./5 Collections Language English Metadata Related items Showing items related by title and MeSH subject.  执行委员会 关于埃博拉问题特别会议 (‎ EBSS/3/INF./5 , 2015 )‎  Consejo Ejecutivo, Reunión extraordinaria sobre el ebola (‎ EBSS/3/INF./5 , 2015 )‎  执行委员会 关于埃博拉问题特别会议 (‎ EBSS/3/INF./1

2015 WHO

18. Ebola Virus Disease Democratic Republic of Congo: External Situation Report 26

Ebola Virus Disease Democratic Republic of Congo: External Situation Report 26 Ebola Virus Disease Democratic Republic of Congo: External Situation Report 26 JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Ebola Virus Disease Democratic Republic of Congo: External Situation Report 26 View/ Open View Statistics Altmetrics Share Other Titles Ebola Situation Report 26 Citation (...) World Health Organization. Regional Office for Africa, Health Emergencies Programme . (‎2017)‎. Ebola Virus Disease Democratic Republic of Congo: External Situation Report 26. World Health Organization. Regional Office for Africa. Collections Language English Metadata Related items Showing items related by title and MeSH subject.  World Health Organization = Organisation mondiale de la Santé (‎ 2019-01-18 )‎  World Health Organization = Organisation mondiale de la Santé (‎ 2019-01-18 )‎  World

2017 WHO

19. Ebola Virus Disease Democratic Republic of Congo: External Situation Report 28

Ebola Virus Disease Democratic Republic of Congo: External Situation Report 28 Ebola Virus Disease Democratic Republic of Congo: External Situation Report 28 JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Ebola Virus Disease Democratic Republic of Congo: External Situation Report 28 View/ Open View Statistics Altmetrics Share Other Titles Ebola Situation Report 28 Citation (...) World Health Organization. Regional Office for Africa, Health Emergencies Programme . (‎2017)‎. Ebola Virus Disease Democratic Republic of Congo: External Situation Report 28. World Health Organization. Regional Office for Africa. Collections Language English Metadata Related items Showing items related by title and MeSH subject.  World Health Organization = Organisation mondiale de la Santé (‎ 2019-01-18 )‎  World Health Organization = Organisation mondiale de la Santé (‎ 2019-01-18 )‎  World

2017 WHO

20. Ebola Virus Disease Democratic Republic of Congo: External Situation Report 27

Ebola Virus Disease Democratic Republic of Congo: External Situation Report 27 Ebola Virus Disease Democratic Republic of Congo: External Situation Report 27 JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Ebola Virus Disease Democratic Republic of Congo: External Situation Report 27 View/ Open View Statistics Altmetrics Share Other Titles Ebola Situation Report 27 Citation (...) World Health Organization. Regional Office for Africa, Health Emergencies Programme . (‎2017)‎. Ebola Virus Disease Democratic Republic of Congo: External Situation Report 27. World Health Organization. Regional Office for Africa. Collections Language English Metadata Related items Showing items related by title and MeSH subject.  World Health Organization = Organisation mondiale de la Santé (‎ 2019-01-18 )‎  World Health Organization = Organisation mondiale de la Santé (‎ 2019-01-18 )‎  World

2017 WHO

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