PYODERMA GANGRENOSUM
DermAtlas, 2001 See article at dermatlas.med.jhmi.edu
[len:46921, cleaned:] DermAtlas: Online Dermatology Image Library dermatology image,pyoderma gangrenosum,neutrophilic dermatosis,inflammatory bowel disease Match ALL words Match ANY word Your query returned at least 10 Images Click on the IMAGE to see an enlargement. The number of images has been limited to 10 per page. © 2001-05, Image Name: pyoderma_gangrenosum_1_050419 File Type: jpg Diagnosis: / / Category: Body Site: Age: 51 years Contributor: Description: multiple2-5 cm violaceous nodules and plaques many with central crusting and ulceration with undermined borders Comments: This 51-year-old woman with a history of ulcerative colitis, perforated diverticulitis, episcleritis developed red to violaceous tender fluctuant nodules on her legs. Many lesions ruptured and drained sterile seropurulent fluid. She developed a persistently fever and elevated white blood count with a left shift. Numerous blood cultures, urine cultures, and chest X-rays failed to show a source of infection. Biopsies of the leg lesions showed a dermal abscess with overlying mixed and acute chronic inflammation. A second biopsy showed mixed lymphocytic and neutrophilic dermatitis. A third biopsy showed a subcorneal pustular dermatosis. All of these findings were felt to be consistent with pyoderma gangrenosum or an infection, but special stains and cultures revealed no evidence of infection with bacteria, acid fast bacilli or fungi. She improved after 3 days of intravenous immunoglubulin at 35 grams per dose. Related Images: © 2001-05, Image Name: pyoderma_gangrenosum_2_050419 File Type: jpg Diagnosis: / / Category: Body Site: Age: 51 years Contributor: Description: violaceous nodules and draining ulcer Comments: This 51-year-old woman with a history of ulcerative colitis, perforated diverticulitis, episcleritis developed red to violaceous tender fluctuant nodules on her legs. Many lesions ruptured and drained sterile seropurulent fluid. She developed a persistently fever and elevated white blood count with a left shift. Numerous blood cultures, urine cultures, and chest X-rays failed to show a source of infection. Biopsies of the leg lesions showed a dermal abscess with overlying mixed and acute chronic inflammation. A second biopsy showed mixed lymphocytic and neutrophilic dermatitis. A third biopsy showed a subcorneal pustular dermatosis. All of these findings were felt to be consistent with pyoderma gangrenosum or an infection, but special stains and cultures revealed no evidence of infection with bacteria, acid fast bacilli or fungi. She improved after 3 days of intravenous immunoglubulin at 35 grams per dose. Related Images: © 2001-05, Image Name: pyoderma_gangrenosum_3_050419 File Type: jpg Diagnosis: / / Category: Body Site: Age: 51 years Contributor: Description: tender violaceous nodules Comments: This 51-year-old woman with a history of ulcerative colitis, perforated diverticulitis, episcleritis developed red to violaceous tender fluctuant nodules on her legs. Many lesions ruptured and drained sterile seropurulent fluid. She developed a persistently fever and elevated white blood count with a left shift. Numerous blood cultures, urine cultures, and chest X-rays failed to show a source of infection. Biopsies of the leg lesions showed a dermal abscess with overlying mixed and acute chronic inflammation. A second biopsy showed mixed lymphocytic and neutrophilic dermatitis. A third biopsy showed a subcorneal pustular dermatosis. All of these findings were felt to be consistent with pyoderma gangrenosum or an infection, but special stains and cultures revealed no evidence of infection with bacteria, acid fast bacilli or fungi. She improved after 3 days of intravenous immunoglubulin at 35 grams per dose. Related Images: © 2001-05, Image Name: pyoderma_gangrenosum_4_050419 File Type: jpg Diagnosis: / / Category: Body Site: Age: 51 years Contributor: Description: tender violaceous putsules Comments: This 51-year-old woman with a history of ulcerative colitis, perforated diverticulitis, episcleritis developed red to violaceous tender fluctuant nodules on her legs. Many lesions ruptured and drained sterile seropurulent fluid. She developed a persistently fever and elevated white blood count with a left shift. Numerous blood cultures, urine cultures, and chest X-rays failed to show a source of infection. Biopsies of the leg lesions showed a dermal abscess with overlying mixed and acute chronic inflammation. A second biopsy showed mixed lymphocytic and neutrophilic dermatitis. A third biopsy showed a subcorneal pustular dermatosis. All of these findings were felt to be consistent with pyoderma gangrenosum or an infection, but special stains and cultures revealed no evidence of infection with bacteria, acid fast bacilli or fungi. She improved after 3 days of intravenous immunoglubulin at 35 grams per dose. Related Images: © 2001-05, Image Name: pyoderma_gangrenosum_5_050419 File Type: jpg Diagnosis: / / Category: Body Site: Age: 51 years Contributor: Description: multiple2-5 cm violaceous nodules and plaques many with central crusting and ulceration with undermined borders Comments: This 51-year-old woman with a history of ulcerative colitis, perforated diverticulitis, episcleritis developed red to violaceous tender fluctuant nodules on her legs. Many lesions ruptured and drained sterile seropurulent fluid. She developed a persistently fever and elevated white blood count with a left shift. Numerous blood cultures, urine cultures, and chest X-rays failed to show a source of infection. Biopsies of the leg lesions showed a dermal abscess with overlying mixed and acute chronic inflammation. A second biopsy showed mixed lymphocytic and neutrophilic dermatitis. A third biopsy showed a subcorneal pustular dermatosis. All of these findings were felt to be consistent with pyoderma gangrenosum or an infection, but special stains and cultures revealed no evidence of infection with bacteria, acid fast bacilli or fungi. She improved after 3 days of intravenous immunoglubulin at 35 grams per dose. Related Images: © 2001-05, Image Name: pyoderma_gangrenosum_1_041024 File Type: jpg Diagnosis: Category: / Body Site: / Age: 30 years Contributor: Description: punched out undermined ulcers with yellow exudate on a violaceous hyperpigmented fibrotic base Comments: This 30-year-old man had recurrent painful ulcers of the right ankle which healed with scarring. The clinical course and histologic findings were typical of pyoderma gangrenosum. Cultures were negative for bacteria, atypical mycobacteria, and fungi, and a thorough medical evaluation failed to reveal an associated underlying medical disorder. These ulcers healed with high dose oral steroids. Related Images: © 2001-05, Image Name: pyoderma_gangrenosum_2_041024 File Type: jpg Diagnosis: Category: / Body Site: / Age: 30 years Contributor: Description: punched out undermined ulcers with yellow exudate on a violaceous hyperpigmented fibrotic base Comments: This 30-year-old man had recurrent painful ulcers of the right ankle which healed with scarring. The clinical course and histologic findings were typical of pyoderma gangrenosum. Cultures were negative for bacteria, atypical mycobacteria, and fungi, and a thorough medical evaluation failed to reveal an associated underlying medical disorder. These ulcers healed with high dose oral steroids. Related Images: © 2001-05, Image Name: pyoderma_gangrenosum_3_041024 File Type: jpg Diagnosis: Category: / Body Site: / Age: 30 years Contributor: Description: punched out undermined ulcers with yellow exudate on a violaceous hyperpigmented fibrotic base Comments: This 30-year-old man had recurrent painful ulcers of the right ankle which healed with scarring. The clinical course and histologic findings were typical of pyoderma gangrenosum. Cultures were negative for bacteria, atypical mycobacteria, and fungi, and a thorough medical evaluation failed to reveal an associated underlying medical disorder. These ulcers healed with high dose oral steroids. Related Images: © 2001-05, Image Name: neutrophilic_dermatosis_1_040901 File Type: jpg Diagnosis: / Category: / Body Site: Age: 54 years Contributor: Description: crusted ulcerated red to violaceous plaques Comments: This 54-year-old man with myelodysplastic syndrome developed painful ulcerated red plaques on his arms, legs and indurated annular and violaceous plaques studded with pustules and crusts on his chest and neck. Some lesions healed with hyperpigmentation while new lesions continued to appear. Skin biopsies revealed sheets of neutrophils throughout the dermis. Special stains were negative for organisms. Related Images: © 2001-05, Image Name: neutrophilic_dermatosis_2_040901 File Type: jpg Diagnosis: / Category: / Body Site: Age: 54 years Contributor: Description: indurated annular violaceous plaques studded with crusts and pustules Comments: This 54-year-old man with myelodysplastic syndrome developed painful ulcerated red plaques on his arms, legs and indurated annular and violaceous plaques studded with pustules and crusts on his chest and neck. Some lesions healed with hyperpigmentation while new lesions continued to appear. Skin biopsies revealed sheets of neutrophils throughout the dermis. Special stains were negative for organisms. Related Images: Match ALL words Match ANY word Return to the Link directly to this page: http://DermAtlas.med.jhmi.edu/derm/result.cfm?Diagnosis=47670916
