• Antibiotics in Acute Sinusitis
• Effectiveness of Family and Caregiver Interventions on Patient Outcomes among Adults with Cancer or Memory-Related Disorders
• Individuals suffering from diabetes are more susceptible to root caries but not coronal caries compared to those without diabetes
• Esthetic Perception of Direct Composite Veneers are Preferred over Porcelain Veneers
• Magnifying Loupes Can Effectively Reduce Poor Posture Among Dental Professionals
• Myofunctional Therapy May Reduce the Severity of Moderate Obstructive Sleep Apnea
• Insufficient Evidence supporting the use of Antibiotic Prophylaxis in Solid Organ Transplant Patients Prior to Dental Treatment
• Dental Students? Musculoskeletal Disorders (MSD) in Their Clinical Environment
• Positional Therapy May Be Useful for Obstructive Sleep Apnea Patients Undergoing Orthodontic Dental Treatment
• Obstructive Sleep Apnea Management with Home Monitoring
• Complete Prostheses Worn at Night May Aggravate the Apnea-Hypopnea Index in Patients with Obstructive Sleep Apnea
• Viscosupplementation (hyaluronic acid or hylan): Cushioning the blow (to your wallet)?
• Hormone Therapy: Does Timing Make a Difference?
• Vildagliptin / metformin hydrochloride (Eucreas) - Treatment of type 2 diabetes mellitus
• Ranibizumab (Lucentis) - for the treatment of visual impairment due to macular oedema (MO) secondary to retinal vein occlusion
• Mirabegron (Betmiga) - overactive bladder (OAB) syndrome
• Lisdexamfetamine dimesylate (Elvanse) - for attention deficit/hyperactivity disorder (ADHD) in children
• Rifampicin, isoniazid, pyrazinamide, ethambutol hydrochloride (Voractiv) - initial treatment of tuberculosis
• Tafamidis meglumine (Vyndaqel) - treatment of transthyretin amyloidosis in adult patients with stage 1 symptomatic polyneuropathy
• Crizotinib (Xalkori) - Treatment of adults with previously treated anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC).
• Vildagliptin (Galvus) - Treatment of type 2 diabetes mellitus in adults
• Abiraterone (Zytiga) - for the treatment of metastatic castration resistant prostate cancer
• Risk factors for hospital morbidity and mortality after the Norwood procedure: A report from the Pediatric Heart Network Single Ventricle Reconstruction trial
• A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure
• Prehospital epinephrine use and survival among patients with out-of-hospital cardiac arrest
• The risk of catheter-related bloodstream infection with femoral venous catheters as compared to subclavian and internal jugular venous catheters: A systematic review of the literature and meta-analysis
• Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation
• Tumour necrosis factor inhibitors for rheumatoid arthritis
• Newer topical therapies for actinic keratoses
• A systematic review and cost-effectiveness analysis of specialist services and adrenaline auto-injectors in anaphylaxis
• Contrast-enhanced ultrasound using SonoVue (sulphur hexafluoride microbubbles) compared with contrast-enhanced computed tomography and contrast-enhanced magnetic resonance imaging for the characterisation of focal liver lesions and detection of liver meta
• Randomised Assessment of Treatment using Panel Assay of Cardiac markers - Contemporary Biomarker Evaluation (RATPAC CBE)
• Exercise for depression in care home residents: a randomised controlled trial with cost-effectiveness analysis (OPERA)
• Autism diagnosis in children and young people
• Abatacept for treating rheumatoid arthritis after the failure of conventional disease-modifying anti-rheumatic drugs
• Percutaneous vertebroplasty and percutaneous balloon kyphoplasty for the treatment of osteoporotic vertebral fractures
• Omalizumab for the treatment of severe persistent allergic asthma in children aged 6 and over and adults
• Idiopathic pulmonary fibrosis - pirfenidone
• Corneal inlay implantation for correction of Presbyopia
• Insertion of a subcutaneous implantable cardioverter defibrillator for prevention of sudden cardiac death
• Prostate Artery Embolisation for Benign Prostatic Hyperplasia
• Occipital nerve stimulation for intractable chronic migraine
• Monarch External Trigeminal Nerve Stimulation (eTNS) System for depression
• Monarch External Trigeminal Nerve Stimulation (eTNS) System for epilepsy
• Glaucoma - disease-specific review
• Glysure intravascular continuous glucose monitoring system for glycaemic control in intensive care
• Insulin degludec Commissioning Support Summary Sheet
• Dapaglifozin Commissioning Support Summary Sheet
• Strontium ranelate (Protelos): risk of serious cardiac disorders?restricted indications, new contraindications, and warnings
• Recent drug-name confusion: please be vigilant as life-threatening errors may occur
• Cilostazol (Pletal): risks of cardiovascular and bleeding events?indication restricted to second-line treatment and contraindicated with some cardiovascular conditions and medicines
• Insulin degludec (Tresiba): available in additional higher strength than existing insulins?care needed to minimise risk of error, including training for patients
• Attention deficit hyperactivity disorder in children and young people: lisdexamfetamine dimesylate
• Guidelines for the Importance of timing in Parkinsons Medication
• Pressure Ulcer Treatment Strategies: Comparative Effectiveness
• Pressure Ulcer Risk Assessment and Prevention: Comparative Effectiveness
• Otitis Media With Effusion: Comparative Effectiveness of Treatments
• Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings
• Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment: Comparative Effectiveness Update
• Pulmonary Arterial Hypertension: Screening, Management, and Treatment
• Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness
• Comparative Effectiveness of Preventive Pharmacological Treatments for Migraine
• Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs
• Child Exposure to Trauma: Comparative Effectiveness of Interventions Addressing Maltreatment
• Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs
• Effect Size Metric Choices as Factors in Meta-Analytic Statistical Inferences
• Communication and Dissemination Strategies To Facilitate the Use of Medical Evidence
• Canadian Cardiovascular Society/Canadian Heart Rhythm Society joint position statement on the use of remote monitoring for cardiovascular implantable electronic device follow-up
• Canadian Diabetes Association 2013 clinical practice guidelines for the prevention and management of diabetes in Canada : Diabetes in the elderly
• Canadian Diabetes Association 2013 clinical practice guidelines for the prevention and management of diabetes in Canada : Hyperglycemic emergencies in adults
• Canadian Diabetes Association 2013 clinical practice guidelines for the prevention and management of diabetes in Canada : Hypoglycemia
• Follow-up of Colorectal Polyps or Cancer
• Colorectal Screening for Cancer Prevention in Asymptomatic Patients
• Too Much of a Good Thing: The Evidence Behind the Need for a Bisphosphonate Holiday
• Is Personalized Medicine Really the Cure? Looking Through the Lens of Breast Cancer
• Preserving Residual Renal Function
• Health Care: Do Celebrities Know Best?
• Did Abraham Lincoln Have Marfan Syndrome?
• In Search of a Competitive Advantage: A Primer for the Clinician Treating the Anabolic Steroid User
• Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States
• Management of the paediatric patient with acute head trauma
• Working with vaccine-hesitant parents
• Forced Air Warming Units for Adults Undergoing Surgery: Clinical Evidence
• Non-Pharmacological Therapies for the Treatment of Insomnia in Adults: Clinical Evidence and Guidelines
• Transcatheter Aortic Valve Replacement in Severe Aortic Stenosis: A Review of Comparative Durability and Clinical Effectiveness Beyond 12 Months
• Brentuximab for Refractory CD30+ Hodgkin?s Lymphoma: Clinical and Cost-Effectiveness
• Administration of Anesthesia by Anesthesiologists Versus Non-Physicians for Patients Undergoing Cataract Surgery: Clinical Effectiveness, Cost-Effectiveness, and Guidelines
• Beta Human Chorionic Gonadotropin Test for Detection of Early Pregnancy: Clinical Effectiveness, Cost-Effectiveness, and Guidelines
• Compression Bandage Measurement Devices for the use in Adult Patients with Chronic Venous Insufficiency: Clinical Effectiveness
• Techniques for Renal Biopsy: Guidelines
• Vitamin D Supplementation in Long-Term Care Residents: Clinical Evidence and Guidelines
• Pirfenidone - Pulmonary fibrosis (idiopathic, mild to moderate)
• Palonosetron hydrocholoride - Nausea and vomiting (chemotherapy induced) prevention
• Polycythaemia / erythrocytosis
• Laboratory Diagnosis of Functional Iron Deficiency
• Sequencing-Based Tests to Determine Fetal Down Syndrome (Trisomy 21) from Maternal Plasma DNA
• Balloon Sinus Ostial Dilation for Treatment of Chronic Rhinosinusitis
• Multianalyte Testing for the Evaluation of Adnexal Masses
• Special Report: Treatments for Castration-Resistant Metastatic Prostate Cancer
• First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness
• Use Versus Nonuse of Dietary Supplements in Adults Taking Cardiovascular Drugs
• Factors affecting the outcome of fractures of the femoral neck in children and adolescents: a systematic review
• Late-Onset Sepsis in Very Low Birth Weight Infants from Singleton and Multiple-Gestation Births
• Benefits of intensive treadmill exercise training on cardiorespiratory function and quality of life in patients with pulmonary hypertension
• Medical Abortion Follow-up With Serum Human Chorionic Gonadotropin Compared With Ultrasonography: A Randomized Controlled Trial
• Concordance between hysteroscopic impression and endometrial histopathological diagnosis
• Diaper dermatitis care of newborns human breast milk or barrier cream
• A Randomized Controlled Trial of a Self-Regulation Intervention for Older Adults with Asthma
• Effect of low-dose aspirin on functional outcome from cerebral vascular events in women
• A randomized trial comparing conventional and robotically assisted total laparoscopic hysterectomy
• Similar range of motion and function after resurfacing large-head or standard total hip arthroplasty
• Outcomes after coronary computed tomography angiography in the emergency department: a systematic review and meta-analysis of randomized, controlled trials
• Clinical improvement and resorption of calcifications in calcific tendinitis of the shoulder after shock wave therapy at 6 months follow-up. A systematic review and meta-analysis
• Long-term multicentre randomised controlled study of high frequency chest wall oscillation versus positive expiratory pressure mask in cystic fibrosis
• Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled by Established Basal Insulin: A 24-week, randomized, placebo-controlled comparison (GetGoal-l)
• A randomized controlled trial of nurses vs. doctors in the resolution of acute disease of low complexity in primary care
• Phosphodiesterase-5 inhibitors for the treatment of secondary Raynaud`s phenomenon: systematic review and meta-analysis of randomised trials
• Five-year outcomes of probable rheumatoid arthritis treated with methotrexate or placebo during the first year (the PROMPT study)
• A Prognostic Nomogram for Prediction of Recurrence in Desmoid Fibromatosis
• A Simple Tool to Predict End-Stage Renal Disease within 1 Year in Elderly Adults with Advanced Chronic Kidney Disease
• The Effects of Music Therapy on Vital Signs, Feeding, and Sleep in Premature Infants
• Comparison of 2 Different Techniques for Anatomic Reconstruction of the Medial Patellofemoral Ligament: A Prospective Randomized Study
• Initiation of Antiretroviral Therapy Before 6 Months of Age is Associated with Faster Growth Recovery in South African Children Perinatally Infected with Human Immunodeficiency Virus
• Blood pressure-lowering effects of GLP-1 receptor agonists exenatide and liraglutide: a meta-analysis of clinical trials
• Adalimumab, a human anti-TNF monoclonal antibody, outcome study for the prevention of joint damage in Japanese patients with early rheumatoid arthritis: the HOPEFUL 1 study
• Predictive value of the HAS-BLED and ATRIA bleeding scores for the risk of serious bleeding in a ``real-world`` population with atrial fibrillation receiving anticoagulant therapy
• Pharmacologic treatment of pediatric headaches: a meta-analysis
• A Cough Algorithm for Chronic Cough in Children: A Multicenter, Randomized Controlled Study
• Growth differentiation factor 15: a novel risk marker adjunct to the EuroSCORE for risk stratification in cardiac surgery patients
• Acupuncture for gouty arthritis: a concise report of a systematic and meta-analysis approach
• Is Protecting the Healing Ligament Beneficial After Immobilization in External Rotation for an Initial Shoulder Dislocation?
• Predicting survival in patients receiving continuous flow left ventricular assist devices: the HeartMate II risk score
• Systematic Review of Positive Youth Development Programs for Adolescents With Chronic Illness
• Heated, Humidified High-Flow Nasal Cannula Versus Nasal CPAP for Respiratory Support in Neonates
• Sacral nerve stimulation for constipation
• A meta-analysis of endovascular versus surgical reconstruction of femoropopliteal arterial disease
• A multicenter, randomized, controlled study evaluating preventive etanercept on postoperative pain after inguinal hernia repair
• Optimal Dose of Intra-articular Corticosteroids for Adhesive Capsulitis: A Randomized, Triple-Blind, Placebo-Controlled Trial.
• Effects of the Finnish Alzheimer Disease Exercise Trial (FINALEX): A Randomized Controlled Trial
• A pilot randomized controlled trial of a commercial diet and exercise weight loss program in minority breast cancer survivors
• Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial
• Long-term results of a randomized clinical trial comparing Roux-en-Y gastric bypass with vertical banded gastroplasty
• Osteopathic manual treatment and ultrasound therapy for chronic low back pain: a randomized controlled trial
• A clinical prognostic model for the identification of low-risk patients with acute symptomatic pulmonary embolism and active cancer
• Effectiveness of incentive spirometry in patients following thoracotomy and lung resection including those at high risk for developing pulmonary complications
• Self-management intervention for chronic pain in older adults: A randomised controlled trial
• The Effectiveness of Conservative Treatment for Patients With Cervical Radiculopathy: A Systematic Review
• Effectiveness of Energy Conservation Treatment in Reducing Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis
• Phase III, Multicenter, Randomized Trial of Maintenance Chemotherapy Versus Observation in Patients With Metastatic Breast Cancer After Achieving Disease Control With Six Cycles of Gemcitabine Plus Paclitaxel As First-Line Chemotherapy: KCSG-BR07-02
• A natural fiber complex reduces body weight in the overweight and obese: A double-blind, randomized, placebo-controlled study
• Lack of evidence of increased mortality among patients with atrial fibrillation taking digoxin: findings from post hoc propensity-matched analysis of the AFFIRM trial
• Safety and tolerability of the novel inhaled corticosteroid fluticasone furoate in combination with the beta2 agonist vilanterol administered once daily for 52 weeks in patients >=12 years old with asthma: a randomised trial
• Efficacy of cytisine in helping smokers quit: systematic review and meta-analysis
• Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial
• Effect of Psychological Interventions on Depressive Symptoms in Long-Term Rehabilitation After an Acquired Brain Injury: A Systematic Review and Meta-Analysis
• Long-Term Follow-Up of Neonatal Coarctation and Left-Sided Cardiac Hypoplasia
• Systematic review and meta-analysis of randomized clinical trials comparing single-incision versus conventional laparoscopic cholecystectomy
• Prospective Randomized Controlled Trial of Operative Rib Fixation in Traumatic Flail Chest
• Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers
• Rates of radiolucency and loosening after total shoulder arthroplasty with pegged or keeled glenoid components
• Bupropion for smoking cessation in patients hospitalized with acute myocardial infarction: a randomized, placebo-controlled trial
• Hospital Fall Prevention: A Systematic Review of Implementation, Components, Adherence, and Effectiveness
• Meta-analysis of laparoscopic versus open cholecystectomy for patients with liver cirrhosis and symptomatic cholecystolithiasis
• The effects of lidocaine spray and intracuff alkalinized lidocaine on the occurrence of cough at extubation: a double-blind randomized controlled trial
• Epidural versus continuous preperitoneal analgesia during fast-track open colorectal surgery: a randomized controlled trial
• Continuous Femoral Versus Epidural Block for Attainment Of 120 degrees Knee Flexion After Total Knee Arthroplasty: A Randomized Controlled Trial
• Comparative Effectiveness Review: Prostate Cancer Antigen 3 (PCA3) Testing For the Diagnosis and Management of Prostate Cancer
• A Systematic Review and Meta-Analysis of Medical Leech Therapy for Osteoarthritis of the Knee
• Randomized Phase II Study of Ixabepilone or Paclitaxel Plus Carboplatin in Patients With Non-Small-Cell Lung Cancer Prospectively Stratified by Beta-3 Tubulin Status
• Efficiency, efficacy, and safety of EZ-blocker compared with left-sided double-lumen tube for one-lung ventilation
• AVEREL: A Randomized Phase III Trial Evaluating Bevacizumab in Combination With Docetaxel and Trastuzumab as First-Line Therapy for HER2-Positive Locally Recurrent/Metastatic Breast Cancer
• Clipping versus coiling for ruptured intracranial aneurysms: a systematic review and meta-analysis
• Ultrasonography- or Electrophysiology-Guided Suprascapular Nerve Block in Arthroscopic Acromioplasty: A Prospective, Double-Blind, Parallel-Group, Randomized Controlled Study of Efficacy
• Biofeedback-based Cognitive-Behavioral Treatment Compared With Occlusal Splint for Temporomandibular Disorder: A Randomized Controlled Trial
• Infection prevention in long-term care: a systematic review of randomized and nonrandomized trials
• Forced Smoking Abstinence: Not Enough for Smoking Cessation
• Does the Method of Component Fixation Influence Clinical Outcomes After Total Knee Replacement? A Systematic Literature Review
• Phase III, Randomized, Placebo-Controlled Study of Docetaxel in Combination With Zibotentan in Patients With Metastatic Castration-Resistant Prostate Cancer
• Is Cervical Disc Arthroplasty Superior to Fusion for Treatment of Symptomatic Cervical Disc Disease? A Meta-Analysis
• Long-Term Outcomes After Bankart Shoulder Stabilization
• Folate Fortification and Supplementation Do Not Provide Vascular Health Benefits in Type 1 Diabetes
• Randomized clinical trial of goal-directed fluid therapy within an enhanced recovery protocol for elective colectomy
• Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer
• Vildagliptin and pioglitazone in patients with impaired glucose tolerance after kidney transplantation: a randomized, placebo-controlled clinical trial
• Ten-year results of a randomized trial comparing tacrolimus versus cyclosporine a in combination with mycophenolate mofetil after heart transplantation
• Flurbiprofen microgranules for relief of sore throat: a randomised, double-blind trial
• Prognostic implications of nonobstructive coronary artery disease in patients undergoing coronary computed tomographic angiography for acute chest pain
• Biologic Determinants of Tumor Recurrence in Stage II Colon Cancer: Validation Study of the 12-Gene Recurrence Score in Cancer and Leukemia Group B (CALGB) 9581
• Participation after Multidisciplinary Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults: A Systematic Review
• Centralized, Stepped, Patient Preference-Based Treatment for Patients With Post-Acute Coronary Syndrome Depression: CODIACS Vanguard Randomized Controlled Trial
• A Systematic Review of the Probability of Repeated Admission Score in Community-Dwelling Adults
• Flexible-dose fesoterodine in elderly adults with overactive bladder: results of the randomized, double-blind, placebo-controlled study of fesoterodine in an aging population trial
• Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial
• Retrograde Light-guided Laryngoscopy for Tracheal Intubation: Clinical Practice and Comparison with Conventional Direct Laryngoscopy
• Pain Physiology Education Improves Health Status and Endogenous Pain Inhibition in Fibromyalgia: A Double-Blind Randomized Controlled Trial
• Tabalumab in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate and Naive to Biologic Therapy: A Phase II, Randomized, Placebo-Controlled Trial
• A Randomized Controlled Trial to Determine the Effect of a Model of Restorative Home Care on Physical Function and Social Support Among Older People
• Use of Glucocorticoids and Risk of Venous Thromboembolism: A Nationwide Population-Based Case-Control Study
• Pharmacologic Therapy for Primary Restless Legs Syndrome: A Systematic Review and Meta-analysis
• Potentially Avoidable 30-Day Hospital Readmissions in Medical Patients: Derivation and Validation of a Prediction Model
• Uric Acid Measurement Improves Prediction of Cardiovascular Mortality in Later Life
• Contemporary perioperative care strategies
• Comparative efficacy of oral nucleoside or nucleotide analog monotherapy used in chronic hepatitis B: a mixed-treatment comparison meta-analysis
• Gabapentin reduces preoperative anxiety and pain catastrophizing in highly anxious patients prior to major surgery: a blinded randomized placebo-controlled trial
• Micronutrient supplementation and pregnancy outcomes: double-blind randomized controlled trial in China
• Routine pharmacological venous thromboembolism prophylaxis in frail older hospitalised patients: where is the evidence?
• Reassurance After Diagnostic Testing With a Low Pretest Probability of Serious Disease: Systematic Review and Meta-analysis
• A double-blind randomized trial of wound and intercostal space infiltration with ropivacaine during breast cancer surgery: effects on chronic postoperative pain
• Efficacy of supplemental peripheral nerve blockade for hip fracture surgery: multiple treatment comparison
• Using socio-demographic and early clinical features in general practice to identify people with lung cancer earlier
• Acute rejection characteristics from a prospective, randomized, double-blind, placebo-controlled multicenter trial of early corticosteroid withdrawal
• Protective Effects of Tranexamic Acid on Clopidogrel Before Coronary Artery Bypass Grafting: A Multicenter Randomized Trial
• Intraoperative infusion of 0.6-0.9 microg.kg(-1).min(-1) remifentanil induces acute tolerance in young children after laparoscopic ureteroneocystostomy
• Efficacy and safety of adjunctive anticoagulation in patients with lung cancer without indication for anticoagulants: a systematic review and meta-analysis
• Intravenous acetaminophen reduces postoperative nausea and vomiting: a systematic review and meta-analysis
• Partial anterior vs partial posterior fundoplication following transabdominal esophagocardiomyotomy for achalasia of the esophagus: meta-regression of objective postoperative gastroesophageal reflux and dysphagia
• Atrial fibrillation and the risk of sudden cardiac death: the atherosclerosis risk in communities study and cardiovascular health study
• Exploring outcomes of a nurse practitioner-managed cardiac surgery follow-up intervention: a randomized trial
• Comparison of Complex Versus Simple Activity of Daily Living Staging: Validation of Simple Stages
• The effectiveness of a manual therapy and exercise protocol in patients with thumb carpometacarpal osteoarthritis: a randomized controlled trial
• R-CVP Versus R-CHOP Versus R-FM for the Initial Treatment of Patients With Advanced-Stage Follicular Lymphoma: Results of the FOLL05 Trial Conducted by the Fondazione Italiana Linfomi
• Low-Carbohydrate Diet for the Treatment of Gestational Diabetes: A randomized controlled trial
• Omega-3 fatty acids for the prevention of recurrent symptomatic atrial fibrillation: results of the FORWARD (Randomized Trial to Assess Efficacy of PUFA for the Maintenance of Sinus Rhythm in Persistent Atrial Fibrillation) trial
• Patterns of Inpatient Care for Newly Diagnosed Immune Thrombocytopenia in US Children`s Hospitals
• Impact of Iyengar Yoga on Quality of Life in Young Women with Rheumatoid Arthritis
• Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled With Newly Initiated and Continuously Titrated Basal Insulin Glargine: A 24-Week, Randomized, Placebo-Controlled Study (GETGOAL-DUO-1)
• The effects of psychosocial strategies on anxiety and depression of patients diagnosed with prostate cancer: A systematic review
• Cost-effectiveness of induction of labour at term with a Foley catheter compared to vaginal prostaglandin E gel (PROBAAT trial)
• Spontaneous intestinal perforation in extremely low birth weight infants: association with indometacin therapy and effects on neurodevelopmental outcomes at 18-22 months corrected age
• Performance Analysis of EuroSCORE II Compared to the Original Logistic EuroSCORE and STS Scores for Predicting 30-Day Mortality After Transcatheter Aortic Valve Replacement
• Stroke-related Early Tracheostomy versus Prolonged Orotracheal Intubation in Neurocritical Care Trial (SETPOINT): a randomized pilot trial
• Three-Gene Immunohistochemical Panel Adds to Clinical Staging Algorithms to Predict Prognosis for Patients With Esophageal Adenocarcinoma
• Otitis media - chronic suppurative
• NSAIDs - prescribing issues
• Irritable bowel syndrome
• Diarrhoea - adult's assessment
• Dermatitis - contact
• Cost of neuromodulation therapies for overactive bladder: percutaneous tibial nerve stimulation versus sacral nerve stimulation
• Health benefits and cost effectiveness of endoscopic and nonendoscopic cytosponge screening for Barrett's esophagus
• Insulin delivery and glucose monitoring methods: future research needs
• Marketing authorisations under exceptional circumstances for oncology drugs: an analysis of approval and reimbursement decisions of four drugs
• Fluorescence In Situ Hybridization (FISH) or Other In Situ Hybridization (ISH) testing of uterine cervical cells to predict precancer and cancer
• Crizotinib (Xalkori®) for the treatment of anaplastic lymphoma kinase (ALK) positive advanced non-small cell lung cancer (NSCLC)
• Intravascular diagnostic procedures and imaging techniques versus angiography alone in coronary artery stenting: comparative effectiveness review
• Efficacy and safety of screening for postpartum depression
• Assessment and management of chronic cough
• Outpatient case management for adults with medical illness and complex care needs
• Child and adolescent exposure to trauma: comparative effectiveness of interventions addressing trauma other than maltreatment or family violence
• Technology assessment on genetic testing or molecular pathology testing of cancers with unknown primary site to determine origin
• Familial mediterranean fever (FMF)
• Interleukin 28B (IL28B) testing to predict response to treatment of hepatitis C virus (HCV) infection
• Kabuki syndrome
• PreOvar KRAS-variant test for ovarian cancer
• C-leg prostheses (Otto Bock HealthCare LP) for patients with above-knee amputation
• Coflex interlaminar stabilization device (Paradigm Spine LLC) for treatment of lumbar spinal stenosis
• CyberKnife robotic radiosurgery system (Accuray Inc.) for treatment of prostate cancer
• Impella recover LP 2.5 percutaneous cardiac support system (Abiomed Inc.) for patients undergoing high-risk percutaneous coronary intervention (PCI)
• iStent trabecular micro-bypass stent (Glaukos Corp.) for treatment of primary open-angle glaucoma
• MindStreams cognitive health assessment (NeuroTrax Corp.) product suite (U.S. Clinical Edition) for assessing mild cognitive impairment
• Preoperative whole-body bathing with chlorhexidine gluconate 4% for prevention of surgical site infection
• BRAF p.Val600Glu testing in papillary thyroid carcinoma
• Ehlers-danlos syndrome (EDS), classic type
• Continuous passive motion for the treatment of joint contractures of the extremities
• Epidural steroid injections for low back pain and sciatica
• Laparoscopic CO2 laser ablation for endometriosis
• Magnetic resonance elastography for detecting and staging liver fibrosis
• Mechanical stretching devices for the treatment of joint contractures of the extremities
• Percutaneous left atrial appendage closure to reduce stroke risk in patients with atrial fibrillation
• Positron Emission Tomography (PET) and Combined Positron Emission Tomography-Computed Tomography (PET-CT) for the posttreatment management of cancer of the head and neck
• Serological assays for the diagnosis and management of inflammatory bowel disease: crohn's disease
• Simultaneous Pancreas-Kidney (SPK) transplantation in diabetic patients
• Testosterone for low sexual desire in nonsurgically postmenopausal women
• Transradial, transbrachial, and transulnar approaches for coronary angiography and intervention
• Falls prevention interventions for community-dwelling older persons with cognitive impairment: a systematic review
• Who can provide effective and safe termination of pregnancy care? A systematic review
• Early versus delayed percutaneous coronary intervention for patients with non-ST segment elevation acute coronary syndrome: a meta-analysis of randomized controlled clinical trials
• Use of medications to reduce risk for primary breast cancer: a systematic review for the US Preventive Services Task Force
• Sublingual immunotherapy for the treatment of allergic rhinoconjunctivitis and asthma: a systematic review
• The effectiveness of mobile-health technologies to improve health care service delivery processes: a systematic review and meta-analysis
• Medical management to prevent recurrent nephrolithiasis in adults: a systematic review for an American College of Physicians clinical guideline
• Systematic review and meta-analysis of enhanced recovery after pancreatic surgery with particular emphasis on pancreaticoduodenectomies
• Effect of lower sodium intake on health: systematic review and meta-analyses
• Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses
• Urological cancer - suspected
• Skin cancer - suspected
• Lung cancer - suspected
• Head/neck cancer - suspected
• Haematological malignancy - suspected
• Gynaecological cancer - suspected
• GI (upper) cancer - suspected
• Children's tumours - suspected
• Breast cancer - suspected
• Brain tumour - suspected
• Bone cancer and sarcoma - suspected
• Palliative cancer care - cough
• MI - secondary prevention
• Infertility
• Varicose veins
• Osteoarthritis
• Opioid dependence
• Obsessive-compulsive disorder
• Migraine
• Menopause
• Lipid modification - CVD prevention
• Febrile seizure
• Feverish children - risk assessment
• Feverish children - management
• CVD risk assessment and management
• Anaemia - B12 and folate deficiency
• Warts and verrucae
• Vaginal discharge
• Urinary tract infection (lower) - women
• Urethritis - male
• Uveitis
• Trichomoniasis
• Tiredness / fatigue in adults
• Thrombophlebitis - superficial
• Teething
• Tamoxifen - managing adverse effects
• Tuberculosis
• Sleep apnoea
• Sinusitis
• Sciatica (lumbar radiculopathy)
• Stroke and TIA
• Sleep disorders - shift work and jet lag
• Schizophrenia
• Rheumatoid arthritis
• Restless legs syndrome
• Rubella
• Retinal detachment
• Renal colic - acute
• Raynaud's phenomenon
• Palpitations
• Palliative cancer care - pain
• Palliative cancer care - malignant ulcer
• Pyelonephritis - acute
• Prostatitis - chronic
• Polymyalgia rheumatica
• Parkinson's disease
• Osteoporosis - steroid-induced
• Otitis media - acute
• Neck pain - whiplash injury
• Neck pain - cervical radiculopathy
• Neck pain - non-specific
• Neck pain - acute torticollis
• Nappy rash
• MRSA in primary care
• Mumps
• Measles
• Insomnia
• Influenza - seasonal
• Incontinence - urinary, in women
• Impetigo
• Hyperhidrosis
• Headache - medication overuse
• Headache - assessment
• Hypercholesterolaemia - familial
• Headache - tension-type
• Headache - cluster
• Head injury
• Gastroenteritis
• Fungal skin infection - scalp
• Fungal skin infection - body and groin
• Fungal skin infection - foot
• Fungal nail infection
• Falls - risk assessment
• Endometriosis
• Eating disorders
• Epilepsy
• Ectopic pregnancy
• Dysmenorrhoea
• Diarrhoea - prevention and advice for travellers
• Depression in children
• DVT prevention for travellers
• Diarrhoea - antibiotic associated
• Deep vein thrombosis
• Cardiac arrest - out of hospital care
• Candida - skin
• Chronic kidney disease - not diabetic
• Chlamydia - uncomplicated genital
• Chilblains
• Carbon monoxide poisoning
• Candida - oral
• Breast cancer - managing family history
• Bipolar disorder
• Bacterial vaginosis
• Benzodiazepine and z-drug withdrawal
• Balanitis
• Back pain - low (without radiculopathy)
• Attention deficit hyperactivity disorder
• Antiplatelet treatment
• Anticoagulation - oral
• Amenorrhoea
• Acne vulgaris
• Atrial fibrillation
• Alopecia areata
• Impact of chondroitin sulphate on health utility in patients with knee osteoarthritis: towards economic analysis
• Whooping cough
• Vitiligo
• Vertigo
• Urinary tract infection (lower) - men
• Ulcerative colitis
• Tinnitus
• Temporomandibular joint disorders
• Scarlet fever
• Styes (hordeola)
• Sickle cell disease
• Scrotal swellings
• Pityriasis rosea
• Pancreatitis - chronic
• Pityriasis versicolor
• Parvovirus B19 infection
• Pancreatitis - acute
• Osteoporosis - prevention of fragility fractures
• Osgood-Schlatter's disease
• Olecranon bursitis
• Neck lump
• Neuropathic pain - drug treatment
• Meibomian cyst
• Mastitis and breast abscess
• Malaria
• Morton's neuroma
• Miscarriage
• Macular degeneration - age-related
• LUTS in men, age-related (prostatism)
• Lyme disease
• Itch - widespread
• Insulin therapy in type 2 diabetes
• Itch in pregnancy
• Insulin therapy in type 1 diabetes
• Hypertension in pregnancy
• Hypercalcaemia
• Hirsutism
• Hepatitis B
• Heart failure - chronic
• Head lice
• Hand foot and mouth disease
• Haematospermia
• HIV infection and AIDS
• Hepatitis C
• Hepatitis A
• Halitosis
• Glandular fever
• Gilbert's syndrome
• Epistaxis
• Dupuytren's disease
• Diabetes - type 1
• Diabetes - type 2
• Depression
• Dementia
• Cough
• Corticosteroids - oral
• Chronic obstructive pulmonary disease
• Cervical cancer and HPV
• Cataracts
• Corticosteroids - topical (skin), nose, and eyes
• Corticosteroids - inhaled
• Constipation in children
• Coeliac disease
• Cervical screening
• Bronchiectasis
• Bowel screening
• Bedwetting (enuresis)
• Baker's cyst
• Bruising
• Breathlessness
• Analgesia - mild-to-moderate pain
• Addison's disease
• Achilles tendinopathy
• Cost-effectiveness and cost-utility of the treatment of chronic hepatitis B with peginterferon alfa-2a, interferon alfa, and lamivudine in Lithuania
• Hormone therapy and risk of lung cancer: a meta-analysis
• Whitlow (staphylococcal and herpetic)
• Vestibular neuronitis
• Urticaria
• Threadworm
• Scabies
• Roundworm
• Paronychia - acute
• Pubic lice
• Pruritus vulvae
• Prostate cancer
• Otitis media with effusion
• Bacterial meningitis / meningococcal septicaemia
• Melanoma and pigmented lesions
• Knee pain - assessment
• Insect bites and stings
• Hypothyroidism
• Hyponatraemia
• Gonorrhoea
• Delirium
• Contraception - emergency
• Common cold
• Chest pain
• Breastfeeding problems
• Boils, carbuncles, and staphylococcal carriage
• Benign paroxysmal positional vertigo
• Breast screening
• Asthma
• Alopecia, androgenetic - female
• Antenatal care - uncomplicated pregnancy

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