Cognitive mediation of panic reduction during an early intervention for panic.
Acta Psychiatrica Scandinavica, 2010
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[Epub ahead of print] Cognitive mediation of panic reduction during an early intervention for panic.
Objective: This study investigated cognitive mediation of improvement in panic disorder (PD) symptomatology during and after an early intervention for panic symptoms in subthreshold and mild PD.
Method: We executed a pragmatic, pre-post, two-group, multi-site, randomized trial of an early intervention for panic symptoms, based on cognitive-behavioural therapy, vs.
Results: First, two of the three subscales of the mediator variable Panic Appraisal Inventory (PAI-anticipation and PAI-coping) significantly mediated residual change in PD symptomatology on the PD Severity Scale-Self Report.
Second, preintervention to postintervention PAI-anticipation and PAI-coping change scores significantly predicted postintervention to follow-up change in PD symptomatology after controlling for other change scores.
Conclusion: The results suggest that changes in cognitions may mediate changes in PD symptomatology and that the process of change is circular.
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