Sweet tasting solutions for reduction of needle-related procedural pain in children aged one to 16 years

Cochrane Database of Systematic Reviews, 2011

Sweet tasting solutions for reduction of needle-related procedural pain in children aged one to 16 years - The Cochrane Library - Harrison - Wiley Online Library from LOGIN Enter e-mail address Enter password REMEMBER ME > > > > DATABASE TOOLS DATABASE MENU FIND ARTICLES OTHER RESOURCES Intervention Review You have full text access to this content Sweet tasting solutions for reduction of needle-related procedural pain in children aged one to 16 years Denise Harrison 1,* , Janet Yamada 2 , Thomasin Adams-Webber 3 , Arne Ohlsson 4 , Joseph Beyene 5 , Bonnie Stevens 6 Editorial Group: Published Online: 5 OCT 2011 Assessed as up-to-date: 4 AUG 2011 DOI: 10.1002/14651858.CD008408.pub2 Copyright © 2011 The Cochrane Collaboration.
Sweet tasting solutions for reduction of needle-related procedural pain in children aged one to 16 years.
Publication History Publication Status: New Published Online: 5 OCT 2011 SEARCH ARTICLE TOOLS Abstract Abstract Background Large numbers of studies have shown that oral sucrose or glucose, with or without non-nutritive sucking given prior to painful procedures result in a significant reduction in behavioral pain responses during or following painful procedures compared with placebo, no treatment or non-nutritive sucking alone, in newborns and infants up to 12 months of age.
It is not known if these pain-reducing effects exist for older infants and children one year to 16 years of age.
Objectives To determine the efficacy of sweet tasting solutions or substances for reducing needle-related procedural pain in children beyond one year of age.
Selection criteria Randomized controlled trials (RCTs) in which children from one year up to 16 years of age, received a sweet tasting solution or substance for needle-related procedural pain.
Control conditions included water, non-sweet tasting substances, pacifier, distraction, no treatment, positioning/containment or breastfeeding.
Data collection and analysis Outcome measures included composite pain scores, physiological or behavioral pain indicators, self-report of pain or parental- or healthcare professional-report of child's pain.
We reported mean differences (MD) with 95% confidence intervals (CI) using fixed-effect or random-effects models as appropriate for continuous outcome measures.
Two studies focused on toddlers and pre-school children receiving sucrose for immunization pain compared with water or no treatment and two studies included school-aged children receiving sweet or unsweetened chewing gum before, or, before and during immunization and blood collection.
Participants in the sucrose group in one study had significantly lower cry duration and behavioral pain scores, compared with the no intervention group, while crying time did not differ between the sucrose and the no intervention group in the other study.