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SUV(max) during 18FDG-PET scanning in small cell lung cancer: Similar information as in non-small cell lung cancer?

Lung Cancer, 2011


[Epub ahead of print] SUV(max) during 18FDG-PET scanning in small cell lung cancer: Similar information as in non-small cell lung cancer? , , , , , , .
Abstract In patients with non-small cell lung carcinoma (NSCLC) fluorine-18 fluorodeoxyglucose positron emission tomography (18FDG-PET)-scanning is shown to be of prognostic value.
Limited results on the prognostic and predictive value of the maximum standard uptake values (SUV(max)) obtained during 18FDG-PET scanning in SCLC are available.
An observational study in 75 chemonaive patients diagnosed with SCLC who underwent a 18FDG-PET scan was performed.
SUV(max) values of the primary tumor were related to the overall survival (OS) and the progression free survival (PFS).
Significant lower SUV(max) values of the primary tumor were observed in patients with stage I-III disease compared to stage IV disease.
In patients with stage IV disease and treatment with chemotherapy, OS and PFS were significantly higher in patients with a high SUV(max).
In patients with SCLC metabolic activity determined using 18FDG-PET (SUV(max)) differed between stage I-III and stage IV diseases.
PMID: 21996089 [PubMed - as supplied by publisher] Full Text Sources
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