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Value of transvaginal ultrasonography in endometrial evaluation of non-bleeding postmenopausal women.

Climacteric, 2010


[Epub ahead of print] Value of transvaginal ultrasonography in endometrial evaluation of non-bleeding postmenopausal women.
Abstract Objective To investigate the value of transvaginal ultrasonography (TVU) in the evaluation of the endometrium in postmenopausal women without vaginal bleeding.
Methods This was a prospective, cohort, observational study which included 259 consecutive, asymptomatic, postmenopausal women who were referred to the outpatient clinics of Shiraz University of Medical Sciences.
All the participants underwent TVU by the same gynecologist at the same time as hysteroscopy and endometrial biopsy were performed.
Endometrial histopathology was considered the gold-standard diagnosis and the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of TVU were calculated on the basis of pathologic reports.
The mean endometrial thickness was found to be 3.83 ± 2.95 mm (range 1-25 mm); it was > 5 mm in 41 (15.8%) patients.
The receiver-operating characteristics curve showed an area under the curve of 0.853 (95% confidence interval 0.788-0.917), indicating a moderate accuracy.
Role of hysteroscopy with endometrial biopsy to rule out endometrial cancer in postmenopausal women with abnormal uterine bleeding.
Value of endometrial thickness measurement for diagnosing focal intrauterine pathology in women without abnormal uterine bleeding.
Endometrial evaluation with transvaginal US and hysterosonography in asymptomatic postmenopausal women with breast cancer receiving tamoxifen.